ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Comparative Proteomics Analysis Identifies L-FABP as a Putative Biomarker of Graft Injury During Liver Transplantation Using the ITRAQ/MRM Approach

    M. Chen, Y. Zhang, M. Han, W. Ju, Q. Zhao, Y. Chen, D. Wang, X. He

    Transplant Center, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

    *Purpose: In liver transplantation, much of factors have a pernicious influence on liver donor quality, such as hepatic steatosis, long term of donor hypotension, cardiac…
  • 2020 American Transplant Congress

    Treatment Strategies to Suppress Donor Specific Antibodies: Highlights from a Decade of Research Experience in a Mouse Model of Allo-Sensitization

    I. Kim, G. Wu, N. Chai, T. Brennan, A. Klein, S. Jordan

    Cedars-Sinai Med Ctr, Los Angeles, CA

    *Purpose: Difficulty in desensitization in highly sensitized patients remain problematic in organ transplantation. For over 12 years, our laboratory has been carrying out an HLA…
  • 2020 American Transplant Congress

    Deceased Donor Body Temperature is Associated with Delayed Graft Function in Kidney Transplant Recipients

    J. Mancinelli1, N. Mahmud2, L. Krumeich1, M. Harhay3, P. P. Reese4, D. Goldberg5, P. Abt6

    1Department of Surgery, University of Pennsylvania, Philadelphia, PA, 2Division of Gastroenterology, University of Pennsylvania, Philadelphia, PA, 3Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, PA, 4Renal-Electrolyte and Hypertension Division, Department of Medicine, Center for Clinical Epidemiolog, University of Pennsylvania, Philadelphia, PA, 5Division of Digestive Health and Liver Diseases, Department of Medicine, University of Miami, Miami, FL, 6Division of Transplant Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, PA

    *Purpose: Delayed graft function (DGF) among kidney transplant recipients complicates the post-operative course and is associated with graft failure. Intentional cooling of the donor may…
  • 2020 American Transplant Congress

    Sirolimus (SRL) versus Everolimus (EVR) versus Mycophenolate (MPA) in Kidney Transplant Recipients Receiving Anti-Thymocyte Globulin Induction (r-ATG), Tacrolimus (TAC), and Prednisone

    H. Tedesco Jr., C. T. Felipe, L. Viana, M. Cristelli, N. Tenório, V. Lima, V. Azevedo, K. Ficher, J. Rezende, R. Demarchi, M. Nakamura, Y. Dreige, G. Ormenesse, J. Taddedo, L. Takara, C. Santos, L. Damasceno, J. Pestana

    Nephrology Division, Hospital Do Rim, Sao Paulo, Brazil

    *Purpose: The aim of this study is to compare the efficacy and safety of SRL versus EVR versus MPA in kidney transplant recipients*Methods: This is…
  • 2020 American Transplant Congress

    Graft and Patient Survival after A2-Incompatible Deceased Donor Kidney Transplantation

    S. Getsin, P. Chiang, S. Yu, K. Jackson, D. Segev, A. Massie

    Johns Hopkins School of Medicine, Baltimore, MD

    *Purpose: The Kidney Allocation System (KAS), implemented in 2014, increased offers of ABO type A2 donor kidneys to type O and B recipients, and A2B…
  • 2020 American Transplant Congress

    Long-Term Outcomes for Living Kidney Donors: A Japanese Single-Center Experience

    K. Hotta, D. Iwami, N. Iwahara, N. Shinohara

    Urology, Hokkaido University Hospital, Sapporo, Japan

    *Purpose: Previous studies suggested that live kidney donors do not have a higher risk of death or end-stage kidney disease (ESKD) than the general population.…
  • 2020 American Transplant Congress

    Outcomes of Early versus Late Rejection in Kidney Transplant Recipients

    A. Jaffer, S. Chong, S. Rai, M. Harber, R. Motallebzadeh

    Centre for Transplantation, Department of Renal Medicine, University College London & Royal Free London NHS Foundation Trust, London, United Kingdom

    *Purpose: Advances in immunosuppression have resulted in significantly improved acute rejection rates and short-term renal graft survival. Several studies have suggested that late rejection (LR)…
  • 2020 American Transplant Congress

    Frailty at Time of Kidney Transplant Evaluation is Associated with Higher Rate of Waitlist Denial

    J. Klein1, A. Jurgensen2, M. Gupta1, N. Herrera1, A. Gupta1, D. Cibrik1

    1Nephrology, University of Kansas Medical Center, Kansas City, KS, 2University of Kansas Medical Center, Kansas City, KS

    *Purpose: To determine the association of patient frailty, as assessed by the Fried frailty score at the time of kidney transplant evaluation (KTE), with kidney…
  • 2020 American Transplant Congress

    Pre- And Post-Transplant (Tx) Clazakizumab (CLZ, Humanized Anti-IL-6 Monoclonal Antibody) Treatment Increased Regulatory T Cell (Treg) Percentage in CD4+ T Cells in HLA-Sensitized Kidney Transplant Patients (HS KTx Pts)

    S. Ge1, M. Chu1, E. D. Ortiz1, A. D. Guzman1, A. Vo2, N. Ammerman2, S. C. Jordan2, M. Toyoda1

    1Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA, 2Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA

    *Purpose: IL-6 is a B cell growth factor and pro-inflammatory cytokine. Inhibition of IL-6 signaling modulates B cell activation and inflammatory process possibly through Treg…
  • 2020 American Transplant Congress

    Belatacept in Kidney Transplant Recipients with Previous Non-Renal Solid Organ Transplants

    O. Cristea, C. Larsen, I. Badell

    Emory Transplant Center, Emory University School of Medicine, Atlanta, GA

    *Purpose: Selective co-stimulatory blockade with belatacept has demonstrated long-term benefits in renal transplantation, with improved glomerular filtration rate and decreased risk of death and graft…
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