ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Calculated Panel Reactive Antibody Values Increase for Kidney Transplant Candidates with HLA-DQA and HLA-DPB Unacceptable Antigens

    E. P. Kransdorf1, C. Murphey2, M. Maiers3, L. Gragert4

    1Cedars-Sinai Heart Institute, Beverly Hills, CA, 2Immunogenetics Lab, Southwest Immunodiagnostics, Inc., San Antonio, TX, 3Bioinformatics Research, Be The Match/National Marrow Donor Program, Minneapolis, MN, 4Department of Pathology, Tulane University School of Medicine, New Orleans, LA

    *Purpose: Calculated panel-reactive antibody (CPRA) is the official metric of sensitization used by the United Network for Organ Sharing (UNOS) for kidney allocation. CPRA includes…
  • 2020 American Transplant Congress

    Use of Sitagliptin versus Placebo to Reduce the Incidence and Severity of Post-Transplant Diabetes after Kidney Transplantation

    H. Wijeweera, J. Hagopian, M. Ramakrishnan, L. Chen, R. Delos Santos

    Washington University in St. Louis, Saint Louis, MO

    *Purpose: Post-transplant diabetes mellitus (PTDM) is a complication in non-diabetic kidney transplant (KT) recipients due weight gain and use of CNI and corticosteroids in immunosuppression…
  • 2020 American Transplant Congress

    Outcomes and Experience with Belatacept in Pediatric Kidney Transplantation

    R. Garro1, P. Winterberg1, R. Liverman2, A. Serluco2, B. Warshaw1, R. George1

    1Emory University, Atlanta, GA, 2Children's Healthcare of Atlanta, Atlanta, GA

    *Purpose: Belatacept is a selective co-stimulation blocker used in adult renal transplantation and has shown improvement in glomerular filtration rate (GFR) compared to calcineurin inhibitors…
  • 2020 American Transplant Congress

    Functional Changes in Metabolic and Malignancy Associated Bacterial Genes in the Post Transplant Intestinal Microbiome

    M. Bhat1, S. Sivaraj1, E. Pasini1, J. Copeland2, J. Allard3, A. Humar1

    1Multi-Organ Transplant, UHN, Toronto, ON, Canada, 2University of Toronto, Toronto, ON, Canada, 3UHN, Toronto, ON, Canada

    *Purpose: Long-term survival of liver transplant (LT) recipients is affected by metabolic and malignant complications. The aim of our study was to examine changes in…
  • 2020 American Transplant Congress

    Assessing Interventions to Improve Patient Care Conducted by Pharmacists at an Outpatient Renal Transplant Clinic within a Collaborative Pharmacy Practice Agreement

    K. Johnson, R. Chelewski, A. Langone, M. Peter, A. Zuckerman

    Vanderbilt University Medical Center, Nashville, TN

    *Purpose: A collaborative pharmacy practice agreement (CPPA) permits pharmacists to perform clinical services under the guidance of a supervising physician without direct physician intervention. We…
  • 2020 American Transplant Congress

    Medication Adherence in Thoracic Transplant Candidates

    K. Pennington1, R. Benzo1, S. Jowsey1, M. Budev2, S. Chandreashekaran3, D. Erasmus4, E. Lease5, D. Levine6, K. Thompson1, D. Yip4, B. Hardaway7, S. Dunlay1, C. Kennedy1

    1Mayo Clinic, Rochester, MN, 2Cleveland Clinic Foundation, Cleveland, OH, 3University of Florida, Gainesville, FL, 4Mayo Clinic, Jacksonville, FL, 5University of Washington, Seattle, WA, 6University of Texas Health Science Center, San Antonio, TX, 7Mayo Clinic, Scottsdale, AZ

    *Purpose: Medication non-adherence is associated with poor outcomes in transplant recipients. It can be challenging to identify candidates at risk for medication non-adherence. The simplified…
  • 2020 American Transplant Congress

    Circulatory Extracellular Vesicles from Lung Allograft Recipients with Chronic Lung Allograft Dysfunction Can Induce LKB1 Dependent Epithelial-Mesenchymal Transition

    M. Rahman, S. Angara, A. Arjuna, M. Smith, R. Bremner, T. Mohanakumar

    Norton Thoracic Institute, St. Joseph’s Hospital and Medical Center, Phoenix, AZ

    *Purpose: Extracellular vesicles (EVs) play important role in physiological and pathological conditions. Recently we demonstrated that circulating exosomes (EVs) with lung self-antigens (SAgs) play important…
  • 2020 American Transplant Congress

    Trust and Transparency in Artificial Intelligence-Aided Immunosuppression Decisions

    J. Clement

    Information and Decision Sciences, University of Minnesota, Minneapolis, MN

    *Purpose: In transplant, there is significant interest in using Artificial Intelligence (including machine learning or predictive models) Clinical Decision Support Systems(AI CDSS). Properly designing and…
  • 2020 American Transplant Congress

    Physician Survey on Using APOL1 Genetic Testing in Live Kidney Donor Selection

    M. Doshi1, E. Gordon2, B. Freedman3, C. Thomas4, C. Glover5, J. Locke6

    1Medicine, University of Michigan, Ann Arbor, MI, 2Surgery, Northwestern University, Chicago, IL, 3Medicine, Wake Forest, Winston-Salem, NC, 4Medicine, University of Iowa, Iowa City, IA, 5N/A, Miami, FL, 6Surgery, University of Alabama, Birmingham, AL

    *Purpose: Live kidney donors of recent African ancestry are at an increased risk of developing end stage kidney disease than matched healthy non-donors. A recent…
  • 2020 American Transplant Congress

    Depletional Induction Improves Kidney Graft and Patient Survival in Recipients with a Previous Liver Transplant in the United States

    S. M. Riad1, N. Lim1, S. Jackson2, A. Matas3, J. Lake1

    1Medicine, University of Minnesota, Minneapolis, MN, 2Fairview Health Services, Minneapolis, MN, 3Surgery, University of Minnesota, Minneapolis, MN

    *Purpose: Induction choices for kidney-after-liver transplant recipients are variable. We examined the impact of kidney induction types on kidney graft and patient survival in liver…
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