Am J Transplant, Volume 20, Suppl 3 Archives - Page 141 of 223 - ATC Abstracts

2020 American Transplant Congress
A Nonhuman Primate Model of Intestinal Transplantation – Technical Aspects and Early Outcomes
R. Schmitz¹, J. Yoon¹, M. Song¹, E. Jelly², A. P. Wax², S. J. Knechtle¹, D. L. Sudan¹, J. Kwun¹
¹Department of Surgery, Duke University Medical Center, Durham, NC, ²Department of Biomedical Engineering, Duke University, Durham, NC
*Purpose: Intestinal transplantation (IT) is the treatment of choice for patients with irreversible intestinal failure that experience complications from total parenteral nutrition. Long-term outcomes after…
2020 American Transplant Congress
The Effect of ANG-3777 on Hepatocyte Growth Factor Receptor C-MET Signaling
L. Paka, I. D. Goldberg
Angion Biomedica, Uniondale, NY
*Purpose: Hepatocyte growth factor (HGF) regulates cell growth, development and tissue repair. HGF activity is mediated by the c-MET signaling pathway. The biological effects of…
2020 American Transplant Congress
Maintenance Steroids in the Setting of Alemtuzumab Induction Post-Kidney Transplant Increases Risk of Infection and Hospital Readmission
A. R. Webb, A. A. Al-Bahou, A. J. Brueckner, A. T. Logan, R. S. Baliga, L. J. Bowman Anger
Tampa General Hospital, Tampa, FL
*Purpose: This study sought to assess the safety of steroid-containing maintenance immunosuppression in the setting of alemtuzumab (ALEM) induction.*Methods: Adult (>18 years) kidney transplant recipients…
2020 American Transplant Congress
Impact of Dialysis and Diabetes on Survival in Recipients of Combined Heart-Kidney Transplant
J. Parekh¹, H. Chau², G. Schnickel², J. Berumen², K. Mekeel²
¹University of California, San Diego, La Jolla, CA, ²Surgery, University of California, San Diego, La Jolla, CA
*Purpose: Mounting data shows a survival benefit of combined heart-kidney transplantation in patients with heart and renal failure. However, little has been done to understand…
2020 American Transplant Congress
Donor-Recipient Genetic Relationship and Outcomes of Living Donor Liver Transplantation (LDLT): Does it Really Matter?
A. M. Elsabbagh¹, A. Mohamed¹, E. M. Elsabbagh², A. Al-Kurd¹, T. Ivanics¹, E. Ulrich¹, T. Kitajima¹, M. Rizzari¹, K. Collins¹, A. Yoshida¹, M. Abouljoud¹, S. Nagai¹
¹Henry Ford Hospital, Detroit, MI, ²University of Chicago Medical Center, Chicago, IL
*Purpose: The impact of donor-recipient genetic relationship on LDLT outcomes has been raised by some recent reports. We sought to study this over a large…
2020 American Transplant Congress
Conversion to Sirolimus to Prevent Recurrent Cytomegalovirus Infection/Disease: A Prospective and Randomized Trial
L. Almeida Viana, M. Pontello Cristelli, G. Basso, D. Wagner Castro Lima Santos, M. Taver Costa Dantas, Y. Cardoso Dreige, L. Damasceno, M. Rika Nakamura, H. Tedesco-Silva, J. Medina-Pestana
Hospital do Rim - UNIFESP, São Paulo, Brazil
*Purpose: Recurrent cytomegalovirus (CMV) infection occurs in 30-35% of kidney transplant recipients after completion of treatment and/or preemptive therapy. There is no consensus on the…
2020 American Transplant Congress
Measuring and Monitoring Equity in Access to Deceased Donor Lung Transplants among Lung Registrations
R. R. Goff¹, E. D. Lease², S. Sweet³, A. Robinson¹, D. Stewart¹
¹Research, United Network for Organ Sharing, Richmond, VA, ²University of Washington, Seattle, WA, ³St. Louis Children's Hospital, St. Louis, MO
*Purpose: In 2018, the Organ Procurement and Transplantation Network (OPTN) published a methodology to measure equity in access to deceased donor kidney transplantation that has…
2020 American Transplant Congress
Dual and Opposite Costimulatory Targeting with a Novel Hybrid Protein Effectively Prevents Renal Warm Ischemia Reperfusion Injury in a Rat Bilateral Kidney Model
J. Guiteras¹, L. De Ramon¹, E. Crespo¹, N. Bolaños¹, P. Fontova¹, M. Jarque¹, A. Torija¹, O. Bestard², J. Grinyó², J. Torras²
¹Experimental Nephrology, IDIBELL, Hospitalet de Llobregat, Spain, ²Bellvitge University Hospital, Hospitalet de Llobregat, Spain
*Purpose: Many studies showed the CTLA4 effectiveness in the inhibition of CD28-CD80/86 costimulatory pathway in transplant and autoimmune diseases. Furthermore, the PD1-PDL1/2 interaction has been…
2020 American Transplant Congress
Immune Checkpoint PD-L1 Pathway as an Effective Platform for Localized Immunomodulation to Attain Indefinite Allogeneic Islet Graft Survival
L. Batra¹, P. Shrestha¹, H. Zhao¹, K. B. Woodward¹, M. Tan¹, O. G. Nuno¹, A. Togay¹, M. M. Coronel², A. J. Garcia², H. Shirwan¹, E. S. Yolcu¹
¹Institute for Cellular Therapeutics and Department of Microbiology and Immunology, University of Louisville, Louisville, KY, ²Petit Institute for Bioengineering and Biosciences, Georgia Institute of Technology, Atlanta, GA
*Purpose: Allogenic islet transplantation is an effective therapeutic approach for the treatment of T1D. However, chronic immunosuppression to control rejection is a major limitation. The…
2020 American Transplant Congress
Benefits of Transplantation Over Chronic Dialysis in Septugenerian ESRD Patients with Diabetes
S. Karhadkar, A. Shaik, A. Di Carlo
Temple University School of Medicine, Philadelphia, PA
*Purpose: In 2016, nearly 125,000 adults in the United States began treatment for end-stage renal disease (ESRD) (i.e., kidney failure requiring dialysis or transplantation). Of…