Am J Transplant, Volume 20, Suppl 3 Archives - Page 14 of 223 - ATC Abstracts

2020 American Transplant Congress
A Population-Based Analysis of Hepatocellular Carcinoma in Children: Identifying Optimal Surgical Treatment
I. A. Ziogas¹, L. K. Matsuoka¹, M. I. Montenovo¹, M. Izzy¹, D. J. Benedetti¹, H. N. Lovvorn III², L. A. Gillis¹, S. P. Alexopoulos¹
¹Vanderbilt University Medical Center, Nashville, TN, ²Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN
*Purpose: Hepatocellular carcinoma (HCC) constitutes 0.5% of childhood malignancies and exhibits poor prognosis. Complete tumor extirpation either by partial liver resection (LR) or liver transplantation…
2020 American Transplant Congress
Epidemiology Cytomegalovirus Infection/Disease in Kidney Transplant Recipients: A Systematic Review of Observational Studies
A. Raval¹, K. Kistler², Y. Tang¹, Y. Murata¹, D. R. Snydman³
¹Merck & Co., Inc., Kenilworth, NJ, ²Evidera, Inc., Waltham, MA, ³Tufts Medical Center, Boston, MA
*Purpose: Efficacy of several CMV anti-viral strategies has been shown in controlled trials for CMV infection/disease in kidney transplant recipients (KTRs). However, a comprehensive analysis…
2020 American Transplant Congress
Experience with a BKV-Specific, Neutralizing Monoclonal Antibody (MAU868) for Treatment of Severe BK Virus Nephropathy (BKVN) after Kidney Transplant (FDA EIND #139112)
S. C. Jordan¹, S. J. Kovacs², J. R. Abend³, N. Ammerman¹, M. Toyoda¹, C. C. Nast¹, E. Huang¹, R. Najjar¹, S. Sethi¹, A. Peng¹, K. Lim¹, M. R. Hodges⁴, A. Vo¹
¹Cedars Sinai Medical Ctr, Los Angeles, CA, ²Novartis Institutes for BioMedical Research, East Hanover, NJ, ³Novartis Institutes for BioMedical Research, Emeryville, CA, ⁴Amplyx Pharmaceuticals, San Diego, CA
*Purpose: BK viral reactivation leading to nephropathy and allograft loss in kidney transplant recipients remains a significant challenge. No effective BKV-therapies are currently available. Management…
2020 American Transplant Congress
Hepatitis C and Racial Disparity in Liver Transplant Waitlist Additions: Separate Not Equal
C. Wang¹, J. Buggs¹, E. Rogers¹, A. Kumar², N. Kemmer³
¹Transplant Surgery, Tampa General Hospital, Tampa, FL, ²Morsani College of Medicine, University of South Florida, Tampa, FL, ³Transplant Hepatology, Tampa General Hospital, Tampa, FL
*Purpose: In 2014, direct-acting antivirals (DAAs) became available as a treatment option for Hepatitis C Virus (HCV) with successful results. Since the implementation of DAAs,…
2020 American Transplant Congress
The Impact of Deceased Donor Maintenance on the Incidence of Delayed Kidney Allograft Function
S. Costa¹, F. Barroso¹, C. Oliveira¹, E. Daher¹, P. Fernandes¹, L. Andrade², R. Esmeraldo³, T. Sandes-Freitas¹
¹Universidade Federal do Ceará, Fortaleza, Brazil, ²Universidade Estadual Paulista Júlio de Mesquita Filho, Botucatu, Brazil, ³Hospital Geral de Fortaleza, Fortaleza, Brazil
*Purpose: To evaluate the risk factors for delayed graft function (DGF) in a Brazilian cohort with high DGF incidence, focusing on variables reflecting donor maintenance.*Methods:…
2020 American Transplant Congress
Mechanisms by Which Donor Bone-Marrow CXCR4+ Foxp3+ Tregs Promote Long-Term Survival of Murine Limb Allografts
L. Wang¹, Z. Wang², R. Han¹, A. Samanta¹, G. Ge¹, L. S. Levin¹, M. H. Levine¹, W. W. Hancock³
¹Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, ²University of Pennsylvania, Philadelphia, PA, ³Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA
*Purpose: Vascularized composite allotransplantation (VCA) allows tissue replacement after devastating loss but is currently limited in application and may be more widely performed if maintenance…
2020 American Transplant Congress
Pancreas Transplant in Chronic Kidney Disease for Type 1 Diabetic Patients
R. A. Choudhury, D. Yoeli, H. B. Moore, H. Yaffe, K. D. Conzen, T. L. Nydam, P. T. Kennealey
Department of Surgery- Division of Transplantation Surgery, University of Colorado Hospital, Aurora, CO
*Purpose: Although both pancreas transplantation alone (PTA) and islet cell transplantation (ICT) have been associated with peri-operative declines in eGFR, the magnitude of decline is…
2020 American Transplant Congress
Association between Sarcopenia and Nutritional Factors in Kidney Transplant Recipients
A. Kosoku¹, J. Uchida¹, T. Ishihara², T. Iwai¹, H. Shimada¹, K. Kabei¹, S. Nishide¹, T. Naganuma¹, T. Nakatani¹
¹Urology, Osaka City University Graduate School of Medicine, Osaka, Japan, ²Innovative and Clinical Research Promotion Center, Gifu University Hospital, Gihu, Japan
*Purpose: Malnutrition is an important risk factor for the development of sarcopenia. Several methods are used for the assessment of nutritional status including serum albumin…
2020 American Transplant Congress
Should Steatotic Livers Be Transplanted Into Pediatric Recipients?
M. MacConmara, C. Feizpour, P. Vagefi, C. Ramirez, L. DeGregorio, C. S. Hwang
UT Southwestern, Dallas, TX
*Purpose: Although steatotic livers are frequently transplanted in the adult population, they are not commonly transplanted in pediatric recipients. We questioned if the outcomes of…
2020 American Transplant Congress
Development and Cell Surface Testing of a Novel Nanofiber Technology for Targeted Delivery of Therapeutic Regulatory T Cells
J. M. Mathew¹, S. Lee², Y. Sambandam¹, L. A. Fraser², T. D. Clemons², A. Kolberg², J. He¹, L. C. Palmer², M. T. McClendon², Z. J. Zhang¹, J. R. Leventhal¹, S. I. Stupp², L. Gallon¹
¹Surgery -Transplant, Northwestern University, Chicago, IL, ²Simpson Querrey Institute, Northwestern University, Chicago, IL
*Purpose: Regulatory CD4+CD25+FOXP3+ T cells (Tregs) have been shown to induce tolerance in transplantation models, and to be increased in their numbers in tolerant human…