Am J Transplant, Volume 20, Suppl 3 Archives - Page 139 of 223 - ATC Abstracts

2020 American Transplant Congress
Tolerant Liver Transplant Patients Have Higher Level of Y RNA Fragments in the Circulation
C. Kuscu¹, A. Wolen¹, A. Bajwa¹, C. Kuscu¹, J. Eason², B. Ramaswami³, D. Maluf¹, G. Mazariegos³, G. Chalasani³, V. Mas¹
¹Transplant Research Institute, James D. Eason Transplant Institute, Department of Surgery, University of Tennessee Health Science Center, Memphis, TN, ²James D. Eason Transplant Institute, Department of Surgery, University of Tennessee Health Science Center, Memphis, TN, ³Thomas E. Starzl Transplantation Institute, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: Tolerance post transplantation continue to be the ultimate goal in transplantation. Circulating small RNAs are one of the best candidates for biomarker studies. To…
2020 American Transplant Congress
Diagnostic Method of Acute Kidney Rejection after Transplantation Using Metabolome Analysis via a Liquid Biopsy Approach
H. Iwamoto
Department of Kidney Transplantation Surgery, Tokyo Medical University, Hachioji Medical Center, Tokyo, Japan
*Purpose: At present, a definitive diagnosis of organ dysfunction after transplantation (such as acute rejection) is dependent on conventional histopathological evaluation using an invasive biopsy…
2020 American Transplant Congress
Assessment of Deceased Donor Kidney and Liver Surgical Recovery Error Rates
R. D. Hasz, S. M. West, H. M. Nathan
Gift of Life Donor Program, Philadelphia, PA
*Purpose: There is no nationally available data related to the incidence of surgical errors in deceased donor organ recoveries or its impact on organ discard…
2020 American Transplant Congress
Memory T Cell-Mediated Rejection is Regulated by FcγRIIB Expression on CD8⁺ T Cells
A. B. Morris, D. F. Pinelli, D. Liu, M. L. Ford
Emory University, Atlanta, GA
*Purpose: Donor-reactive memory T cells represent a potent immunologic barrier to long-term graft survival and tolerance induction. To identify novel pathways that regulate memory T…
2020 American Transplant Congress
Broader Distribution of Kidneys Not Projected to Systematically Favor “Low” Performing OPOs
A. Wilk¹, S. Gustafson², D. Stewart¹, N. Salkowski², D. Zaun², J. Snyder²
¹UNOS, Richmond, VA, ²Hennepin Healthcare Research Institute, Minneapolis, MN
*Purpose: In August 2019, the OPTN Kidney (KI) Transplantation Committee put forth a proposal for public comment to replace DSA and region from KI allocation…
2020 American Transplant Congress
Development of a New Kidney Paired Donation (KPD) Program: Starting a Domino Chain with a Deceased Donor
L. Furian¹, C. Di Bella², C. Silvestre², F. Neri², F. Tuci², M. Cardillo³, E. Cozzi⁴, P. Rigotti¹
¹Kidney and Pancreas Transplantation Unit, University of Padova, Padua, Italy, ²Kidney and Pancreas Transplantation Unit, University of Padova, Italy, Italy, ³Italian National Transplant Center, Rome, Rome, Italy, ⁴Transplant Immunology Unit, Padova University-Hospital, Padua, Padua, Italy
*Purpose: The option of initiating a domino chain of living donor kidney transplants with a deceased donor (DD) has been proposed but never enforced. The…
2020 American Transplant Congress
A Multi-Center Pilot and Feasibility Randomized Clinical Trial of a Home-Based Exercise Program for Patients with Cirrhosis: The Strength Training Intervention
J. C. Lai¹, M. R. Kappus², J. L. Dodge¹, R. Wong¹, Y. Mohamad¹, D. L. Segev³, M. A. McAdams-DeMarco⁴
¹University of California, San Francisco, San Francisco, CA, ²Duke University, San Francisco, NC, ³Johns Hopkins Medical Institute, Baltimore, MD, ⁴Johns Hopkins School of Public Health, Baltimore, MD
*Purpose: Patients with cirrhosis experience progressive physical frailty and functional decline that may ultimately lead to an increased risk of death. We developed the Strength…
2020 American Transplant Congress
Impact of Donor Multidrug-Resistant Organisms on Risk of Recipient Infection
J. A. Anesi¹, E. A. Blumberg¹, J. H. Han², D. H. Lee³, H. Clauss⁴, R. Hasz⁵, E. Molnar⁴, D. Alimenti¹, A. R. Motzer⁴, S. West⁵, W. B. Bilker¹, P. Tolomeo¹, E. Lautenbach¹, T. Prevention Epicenters Program⁶
¹University of Pennsylvania, Philadelphia, PA, ²GlaxoSmithKline, Rockville, MD, ³Drexel University, Philadelphia, PA, ⁴Temple University, Philadelphia, PA, ⁵Gift of Life Donor Program, Philadelphia, PA, ⁶Centers for Disease Control and Prevention, Atlanta, GA
*Purpose: Although there is concern about the use of donor organs that are infected or colonized with multidrug-resistant organisms (MDROs), their impact on solid organ…
2020 American Transplant Congress
High-Risk Antibodies Pre-Transplant Impacts Outcome after Heart Transplantation
J. A. Kobashigawa, M. Kittleson, J. Patel, D. Chang, E. Kransdorf, D. Geft, K. Nishihara, A. Shen, L. Czer, F. Esmailian
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: Pre-transplant circulating antibodies (Abs) are known to impact outcome after heart transplantation (HTx). Abs can now be detected by single-bead assay but also characterized…
2020 American Transplant Congress
Transient Cd4+ T Cell and Cd20+ B Cell Depletion Leads to Prolonged Pig-To-Primate Kidney Xenograft Survival
B. P. Lovasik¹, A. J. Matar¹, D. A. Faber¹, D. V. Mathews¹, C. Breeden¹, S. C. Kim¹, A. J. Tector², A. B. Adams¹
¹Emory University School of Medicine, Atlanta, GA, ²University of Miami, Miami, FL
*Purpose: “Delayed” antibody-mediated xenograft rejection is the one of the most important obstacle to clinical application of pig organ xenografts. The aim of this study…