2020 American Transplant Congress
Early Experience Transplanting Undocumented Immigrants with ESRD at a Single Institution: Outcomes and Challenges
*Purpose: In July of 2016, Minnesota became the second state in the nation to provide coverage for kidney transplantation to patients, regardless of immigration status,…2020 American Transplant Congress
Fate of Donor-Derived Regulatory Dendritic Cells (DCreg) and Augmentation of Host Regulatory T Cells Following Their Infusion Into Prospective Living-Donor Liver Transplant Recipients
Starzl Transplantation Institute, Pittsburgh, PA
*Purpose: Our purpose was to ascertain the fate of ex vivo-generated donor-derived DCreg and their influence on host T cells prior to transplant in a…2020 American Transplant Congress
The Liver Outcome Monitoring Registry Donor Risk Index: A New Measure of Deceased Donor Liver Quality
*Purpose: The liver donor risk index (LDRI) created in 2006 evaluated the relative risk of graft failure, however its weaknesses have limited its use in…2020 American Transplant Congress
Pathogenesis of Polyomavirus BK Nephropathy (BKVN): Insights from Quantitative Proteomics Profiling
*Purpose: Our current understanding of the pathogenesis of BKVN is based primarily on transcriptomics studies. However, proteins are the final effector molecules that mediate tissue…2020 American Transplant Congress
Survey on Solid Organ Pancreas Transplantation in the United States: Plenty of Insulin, Short on Procedures!
*Purpose: For 15 years pancreas transplantation (PT) numbers have paradoxically declined. We sought to understand the drop in all types of PT and to find…2020 American Transplant Congress
Belatacept Suppresses the B-Cell Alloresponse in the Lower Range of Therapeutic Trough Concentrations
1Plexision, Pittsburgh, PA, 2Bristol-Myers-Squibb, Princeton, NJ
*Purpose: Background: Kidney recipients treated with the T-cell costimulation blocker, belatacept, experience a higher incidence of acute cellular rejection (ACR) and lower incidence of donor-specific…2020 American Transplant Congress
Transcriptome-Based Study of Tim-1- B Cells and Tim-1+ Regulatory B Cells
Center for Transplant Science, MGH, Boston, MA
*Purpose: Tim-1 signaling has an important role in maintaining the function of Regulatory B cells. Our previous study suggested Tim-1+ Bregs can prolong the survival…2020 American Transplant Congress
Optimal Recipient Selection and Surgical Complications in Dual Kidney Transplantation
*Purpose: Kidney allocation has recently been modified to allow enhanced utilization of dual kidney transplants (DKT) to reduce organ discards. This study evaluates surgical complications…2020 American Transplant Congress
Liver Transplant with Donation after Cardiac Death versus Donation after Brain Death Donors: Survival and Outcomes at 10 Years
1Surgery, Beth Israel Deaconess Medical Center, Boston, MA, 2Harvard Medical School, Boston, MA
*Purpose: This observational study utilizes the SRTR database to assess liver transplant outcomes after Donation after Cardiac Death (DCD) versus Donation after Brain Death (DBD)…2020 American Transplant Congress
Comparison of Specificity and Sensitivity of Clinical Viability Criteria to Assess Transplantability of High-Risk Donor Livers
*Purpose: Normothermic machine perfusion (NMP) of the liver allows objective assessment before transplantation. To date, Birmingham (BC), Cambridge (CC) and Groningen Criteria (GC; Table 1A)…
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