Am J Transplant, Volume 20, Suppl 3 Archives - Page 129 of 223 - ATC Abstracts

2020 American Transplant Congress
Black Patients with Cirrhosis Have Worse Liver-Related Outcomes: A Large Multicenter Study
N. R. Mazumder¹, K. Atiemo², K. Jackson³, A. Daud⁴, A. Kho³, L. G. Gabra⁵, J. Levitsky¹, D. P. Ladner⁴
¹Gastroenterology and Hepatology, Northwestern University, Chicago, IL, ²Department of Surgery, Tulane Abdominal Transplant Institute, New Orleans, LA, ³Center for Health Information Partnerships, Northwestern University, Chicago, IL, ⁴Transplant Surgery, Northwestern University, Chicago, IL, ⁵Feinberg School of Medicine, Northwestern University, Chicago, IL
*Purpose: Racial disparity is influential in liver cirrhosis. Estimates of its magnitude have been limited by lack of large, longitudinal data that track patients from…
2020 American Transplant Congress
Patterns of Belatacept Use and Risk of Post-Transplant Lymphoproliferative Disorder (PTLD) in US Kidney Transplant Recipients – Analysis of Organ Procurement and Transplantation Network (OPTN) Database
W. S. Cherikh¹, T. Kou², J. Foutz¹, A. Gomez-Caminero²
¹United Network for Organ Sharing (UNOS), Richmond, VA, ²Bristol-Myers Squibb, Princeton, NJ
*Purpose: Belatacept, a selective T-cell costimulation blocker, was approved in 2011 for the prophylaxis of organ rejection in Epstein-Barr virus (EBV)-seropositive kidney transplant recipients. PTLD…
2020 American Transplant Congress
High Laminin Alpha 5 Expression is Observed in the Pancreas of Chronic Pancreatitis Patients and Correlates with Poor Autologous Islet Transplant Outcome
Y. Liu, K. Kumano, S. Vasu, C. M. Darden, M. Lawrence, B. Naziruddin
Baylor University Medical Ctr, Dallas, TX
*Purpose: During chronic pancreatitis (CP), the extracellular matrix (ECM) of the pancreas is destroyed by a vicious cycle of parenchymal autodigestion by digestive exocrine enzymes…
2020 American Transplant Congress
The Role of the Molecular Microscope to Guide Therapy for T-Cell Mediated Rejection in Kidney Transplants
D. Kumar¹, M. Demehin¹, J. Christensen¹, L. Kamal¹, I. Moinuddin¹, M. Levy¹, C. Bhati¹, A. King¹, H. D. Massey¹, P. Halloran², G. Gupta¹
¹Virginia Commonwealth University, Glen Allen, VA, ²ATAGC, Edmonton, AB, Canada
*Purpose: Histologic lesions (I+T) to characterize T-cell mediated rejection (TCMR) can be non-specific. In some cases the inflammation may represent a ‘response to wounding’ rather…
2020 American Transplant Congress
Frailty-Inflammatory Index & Mortality after Kidney Transplantation: Development & Validation
N. Chu, C. Haugen, D. Segev, M. McAdams-DeMarco
Johns Hopkins, Baltimore, MD
*Purpose: Frailty is associated with poor outcomes like delirium, delayed graft function, and mortality, that may result from inflammation after kidney transplant (KT). Despite a…
2020 American Transplant Congress
African American Patient Perceptions of Live Kidney Donation and Educational Health Animations
R. E. Seibert¹, M. Keller², B. Dolph³, T. H. Feeley⁴, L. K. Kayler³
¹Department of Epidemiology and Environmental Health, State University of New York at Buffalo, Buffalo, NY, ²Department of Community Health and Health Behavior, State University of New York at Buffalo, Buffalo, NY, ³Transplant and Kidney Care Regional Center of Excellence, Erie County Medical Center, Buffalo, NY, ⁴Department of Communication, State University of New York at Buffalo, Buffalo, NY
*Purpose: Disparities in pursuit of living donor kidney transplantation (LDKT) among African Americans remain challenging to overcome. Animation-based education is a promising approach to increasing…
2020 American Transplant Congress
Utilization and Outcomes of Simultaneous Liver-Kidney Transplants after Change in Allocation Policy
M. L. Samoylova¹, B. I. Shaw¹, S. J. Kesseli¹, S. Sanoff², Y. Patel², A. S. Barbas¹, L. McElroy¹
¹Surgery, Duke University Hospital, Durham, NC, ²Medicine, Duke University Hospital, Durham, NC
*Purpose: The July 10, 2017 change in simultaneous liver-kidney (SLK) listing policy imposed more stringent criteria on recipient renal function. Recipient outcomes following this change…
2020 American Transplant Congress
Invasive Mould Infection in Transplant Recipients with Influenza: A 5-Year Retrospective Review
P. Phoompoung, S. Husain, L. Singer, A. Humar, D. Kumar
University Health Network, Toronto, ON, Canada
*Purpose: In non-transplant patients with severe influenza illness, an increased rate of invasive mould infection (IMI) has been noted possibly due to the local inflammatory…
2020 American Transplant Congress
Interferon-Beta Acts Directly on T Cells to Promote Foxp3 Acetylation in Regulatory T Cells
F. Fueyo-González, L. Anderson, P. Cravedi, P. S. Heeger, M. Fribourg
Medicine, Icahn School of Medicine at Mount Sinai, New York, NY
*Purpose: Interferon-β (IFNβ) is a type I interferon that binds to its receptor (IFNAR) expressed on immune cells. It has known antiviral and pro-inflammatory activity…
2020 American Transplant Congress
The Gut Microbiota Stimulates Dendritic Cells for Immune Modulation
V. Saxena, W. Piao, L. Hittle, L. Li, T. Simon, C. Palusckievicz, Y. Xiong, T. Zhang, M. Shirkey, E. F. Mongodin, J. S. Bromberg
University of Maryland, Baltimore, Baltimore, MD
*Purpose: The gut microbiota is a driving force in host immune regulation, and thus a potential target for intervention and drug development. We previously showed…