ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Perioperative Results of Lung Transplantation in a Newly Established, High-Volume Lung Transplantation Center in China

    F. Xiao1, Z. Zhang1, H. Feng1, M. Li2, W. Chen3, C. Liang1, J. Chen3

    1Department of Thoracic Surgery, China-Japan Friendship Hospital, Beijing, China, 2Department of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, China, 3Department of Lung Transplantation, China-Japan Friendship Hospital, Beijing, China

    *Purpose: The number of patients with end-stage lung disease is huge in China, lung transplantation is the only effective method. By presenting the perioperative results…
  • 2020 American Transplant Congress

    Comparison of Metabolic Outcomes after Pancreas Transplantation between DBD (Donors after Brainstem Death) and DCD (Donors after Circulatory Death) Grafts

    J. Gopal, A. McLean, J. Crane, P. Herbert, F. Dor, M. Reddy, D. Taube, V. Papalois, A. Muthusamy

    Imperial College Renal and Transplant Centre, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom

    *Purpose: DCD pancreas transplantation has become common with equivalent graft survival as that of DBD grafts, but are the metabolic outcomes similar? Given the lack…
  • 2020 American Transplant Congress

    Donor-Derived Cell-Free DNA for Detection of Cell-Mediated Rejection in Low Risk Kidney Transplant Patients

    S. Anand, L. Dong, M. Fife, J. Krong, S. Dow, D. Morris, T. Srinivas

    Intermountain Medical Center, Murray, UT

    *Purpose: Donor-derived cell free DNA (dd-cfDNA) is an emerging non-invasive biomarker for kidney allograft rejection. This has not been externally validated in low risk population.…
  • 2020 American Transplant Congress

    Granulocyte-Colony Stimulating Factor (G-CSF) and Granulocyte-Macrophage CSF (GM-CSF) Administration Enriches for Highly Suppressive CD4+CD45RA–Foxp3hi Cells in Leukapheresis Products of Rhesus Monkeys

    K. Sasaki, Y. Wang, L. Lu, J. Hughes, V. Vujevich, A. W. Thomson, M. B. Ezzelarab

    Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA

    *Purpose: In humans, CD4+CD45RA-Foxp3hi T cells comprise a regulatory T cell (Treg) subset with highly suppressive function. We have previously shown that granulocyte-colony stimulating factor…
  • 2020 American Transplant Congress

    Autophagy Attenuates Renal Allograft Interstitial Fibrosis by Regulating the EndMT Induced by TNF-α

    Z. Gui, C. Suo, Z. Wang, S. Fei, Z. Han, J. Tao, H. Chen, L. Sun, X. Ju, R. Tan, M. Gu

    Jiangsu Province Hospital, Nanjing, China

    *Purpose: Kidney interstitial fibrosis is a significant cause of allograft failure in kidney transplantation. Autophagy is a self-digestive process that eliminates impaired or aged proteins…
  • 2020 American Transplant Congress

    Effect of Rituximab Dose as Induction Therapy in ABO Incompatible Living Kidney Transplantation A Systemic Review and Network Meta Analysis

    S. Hwang1, W. Park2, K. Kim1, S. Lee1, J. Song1

    1Inha University, Incheon, Korea, Republic of, 2Keimyung University, Daegu, Korea, Republic of

    *Purpose: ABO-incompatible living kidney transplantation (ABOILKT) has steadily become more widespread. However, the optimal immunosuppressive regimen for ABOILKT remains uncertain. We aimed to determine the…
  • 2020 American Transplant Congress

    Effects of Kidney Transplantation on Cystogenesis in Kidneys Procured from a Deceased Donor with Autosomal Dominant Polycystic Kidney Disease

    M. C. Chumley1, H. Kim2, D. M. Williams3, V. Kumar3, M. Mrug3

    1University of Alabama at Birmingham, Birmingham, AL, 2Radiology, University of Alabama at Birmingham, Birmingham, AL, 3Nephrology, University of Alabama at Birmingham, Birmingham, AL

    *Purpose: Autosomal Dominant Polycystic Kidney Disease (ADPKD) patients are not routinely considered as kidney donors for renal transplantation. This is partially due to a concern…
  • 2020 American Transplant Congress

    The Role of mTOR Inhibitors on Cardiovascular Aging in Renal Transplanted Patients with Chronic Graft Dysfunction

    G. Castellano1, B. Infante1, P. Pontrelli1, R. Franzin1, F. Rascio1, C. Prisciandaro2, L. Gesualdo1, N. Coviello3, G. Grandaliano3, G. Stallone3

    1Emergency and Organ Transplantation, University of Bari, Bari, Italy, 2University of Foggia, Foggia, Italy, 3Emergency and Organ Transplantation, University of Foggia, Foggia, Italy

    *Purpose: Chronic Kidney Disease (CKD) is strongly associated with increased circulatory complications that can lead to accelerated cardiovascular aging. During CKD, persistent oxidative stress triggered…
  • 2020 American Transplant Congress

    A Mouse Model of Non-MHC Mismatches Recapitulates Chronic Allograft Dysfunction and I-IFTA

    V. Pavlov1, F. Garzon1, R. Haroon Al Rasheed2, K. Banu1, F. ElSalem1, L. Li1, E. Cody1, M. Planoutene1, N. Chun1, Z. Zhang1, J. Leventhal1, B. Murphy1, P. Heeger1, M. C. Menon1

    1Medicine, Mount Sinai School of Medicine, New York, NY, 2Pathology, Mount Sinai School of Medicine, New York, NY

    *Purpose: Fibrotic and atrophic changes or IF/TA is an important cause of graft loss. We reported that genome-wide donor-recipient non-HLA mismatches independently correlate with Banff…
  • 2020 American Transplant Congress

    Patient Attitudes Regarding Contraception and Pregnancy after Transplantation

    P. Puerzer1, T. McIntosh2, C. Sammons3, N. Casciello3, T. Fallah3, M. Norris3, M. Sumit4, J. DuBois5, A. Iltis6, D. Sawinski1

    1Univ of Pennsylvania, Philadelphia, PA, 2Washington Univ in St Louis, St Louis, MO, 3Pharmacy, Hospital of the Univ of Pennsylvania, Philadelphia, PA, 4Columbia Univ, New York, NY, 5Washington Univ in St Louis, St. Louis, MO, 6Wake Forest Univ, Winston-Salem, NC

    *Purpose: Professional society recommendations regarding contraception and pregnancy after transplantation exist but little is known about patient attitudes.*Methods: We conducted a survey of female transplant…
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