ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Association between Mycoplasma and Ureaplasma Airway Colonization, Ammonia Levels and Outcomes Post Lung Transplantation

    B. Buzo1, J. Preiksaitis1, K. Halloran2, J. Nagendran3, D. Townsend4, N. Zelyas5, W. Sligl4

    1Infectious Diseases, Univ. of Alberta, Edmonton, AB, Canada, 2Pulmonary Medicine, Univ. of Alberta, Edmonton, AB, Canada, 3Cardiac Surgery, Univ. of Alberta, Edmonton, AB, Canada, 4Critical Care Medicine, Univ. of Alberta, Edmonton, AB, Canada, 5Lab Med & Pathology, Univ. of Alberta, Edmonton, AB, Canada

    *Purpose: Hyperammonemia syndrome (HS) is a rare complication that can occur after lung transplantation. This syndrome is characterized by increased ammonia levels with altered sensorium,…
  • 2020 American Transplant Congress

    Survival after Lung Transplantation by Discharge Immunosuppressive Regimen: An Analysis of Organ Procurement and Transplantation Network Data

    W. S. Cherikh1, B. J. Plucinski1, S. Palmer2, W. E. Fitzsimmons3

    1United Network for Organ Sharing, Richmond, VA, 2Duke University Hospital, Durham, NC, 3Fitzsimmons LLC, Vernon Hills, IL

    *Purpose: As the optimal immunosuppressive (IS) regimen after lung (LU) transplant (TX) is unknown, we conducted an analysis to compare the effect of four different…
  • 2020 American Transplant Congress

    TRANSBIO Study: Clinical Evaluation of Immunobiogram, a Novel In Vitro Diagnostic Immunoassay to Guide Adjustment of Immunosuppressive Therapy in Kidney Transplantation

    J. Pascual1, C. Jiménez2, M. Krajewska3, C. Kotton4, D. Seron5, J. Portolés6, O. Witzke7, S. S. Sorensen8, A. Andrés9, T. Díez10, A. Ortega10, I. Portero10

    1Consorci Mar Parc de Salut, Barcelona, Spain, 2La Paz Hospital, Madrid, Spain, 3Wroclaw Medical University, Wroclaw, Poland, 4Massachusetts General Hospital, Boston, MA, 5Vall d’Hebron Hospital, Barcelona, Spain, 6Puerta de Hierro Mahadahonda Hospital, Madrid, Spain, 7University Hospital Essen, University Duisburg-Essen, Essen, Germany, 8Rigshospitalet, Copenhagen, Denmark, 912 de Octubre Hospital, Madrid, Spain, 10Biohope Scientific Solutions for Human Health SL, Madrid, Spain

    *Purpose: Immunobiogram (IMBG) is a first-in-class blood-based pharmacodynamic immunoassay that provides the sensitivity/resistance profile of each patient’s lymphocytes to a panel of immunosuppressive drugs (IS).…
  • 2020 American Transplant Congress

    Identification of Molecular Markers for Liver Cirrhosis (NASH) by Single-Nucleus RNA Sequencing

    C. Kuscu1, A. Mouhammed2, C. Kuscu3, A. R. Wolen3, J. D. Eason3, D. Maluf3, V. Mas3

    1Dept of Surgery, Transplant Research Institute, James D. Eason Transplant Institute, University of Tennessee Health Science Center, Memphis, TN, 2Bioinformatics, University of Tennessee Health Science Center, Memphis, TN, 3Department of Surgery, University of Tennessee Health Science Center, Memphis, TN

    *Purpose: Non-alcoholic fatty liver disease (NAFLD) is a progressive disease and it constitutes a significant portion of the chronic liver diseases that affected more than…
  • 2020 American Transplant Congress

    Genetic Testing of Living Related Donors for Inherited Renal Disease Improves Evaluation and Promotes Informed Choice of At-Risk Living Donors

    C. P. Thomas1, M. E. Freese1, D. A. Katz2

    1Internal Medicine, University of Iowa, Iowa City, IA, 2Surgery, University of Iowa, Iowa City, IA

    *Purpose: Living kidney donors (LKDs) with a family history of kidney disease are at higher risk of end-stage renal disease (ESRD) compared to LKDs without…
  • 2020 American Transplant Congress

    Liver Transplantation for Patients with Cholangiocarcinoma: A Systematic Review and Meta-Analysis of Survival Rates

    I. A. Ziogas1, K. P. Economopoulos2, M. H. Hayat1, L. K. Matsuoka1, M. I. Montenovo1, M. Izzy1, S. P. Alexopoulos1

    1Vanderbilt University Medical Center, Nashville, TN, 2Duke University Medical Center, Durham, NC

    *Purpose: Liver transplant (LT) accompanied by neoadjuvant chemoradiation has emerged as the only curative option for unresectable cholangiocarcinoma (CCA). Although numerous centers have published their…
  • 2020 American Transplant Congress

    Living Donor Gender Disparities Vary by Donor-Recipient Familial Relationship

    Y. Chen1, Y. Hung2, C. de Crescenzo1, C. Rickert1, Y. Hsu3, H. Yeh1, D. Chang1

    1Department of Surgery, Massachusetts General Hospital, Boston, MA, 2Department of Surgery, Sinai Hospital of Baltimore, Baltimore, MA, 3Department of Social and Behavioral Sciences, Harvard School of Public Health, Boston, MA

    *Purpose: Women are more likely to be living transplant donors and less likely to be recipients. It has been difficult to distinguish how much of…
  • 2020 American Transplant Congress

    Transplant Regimen Adherence for Kidney Recipients by Engaging Information Technologies: Update on the Take It Trial

    E. Yoon1, S. Hurr1, L. Curtis1, D. Ladner2, S. Nair3, M. S. Wolf1

    1Center for Applied Health Research on Aging (CAHRA), Northwestern University Feinberg School of Medicine, Chicago, IL, 2Surgery, Northwestern Medicine, Chicago, IL, 3Nephrology and Hypertension, Mayo Clinic, Scottsdale, AZ

    *Purpose: In 2017, the TAKE IT trial began its evaluation of a multifaceted, technology-enabled, transplant center-based intervention to monitor medication adherence behaviors among Kidney Transplant…
  • 2020 American Transplant Congress

    Kidney after Intestinal Transplantation: A Comparison with Combined Kidney with Intestinal Transplant. A UNOS Database Analysis

    A. Sharfuddin, M. Panezai, O. Adebiyi, T. Taber, M. Yaqub

    Indiana University School of Medicine, Indianapolis, IN

    *Purpose: There is limited data on outcomes for patients receiving a isolated kidney transplant (KAIT) after any prior Multi-organ or Isolated Intestinal transplant (IT). We…
  • 2020 American Transplant Congress

    Immunomodulation with FasL Presenting Biomaterials Achieves Long-Term Survival of Allogeneic Islets in the Absence of Chronic Immunosuppression in a Non-Human Primate Model

    J. Lei1, H. Deng1, T. Chen1, K. Lee1, C. Peters1, Z. Yang1, K. Deng1, G. Rickert1, I. Rosales1, N. Serifis1, M. Coronel2, M. Hunckler2, E. Yolcu3, H. Shirwan3, A. García2, J. Markmann1

    1Surgery, Mass General, Boston, MA, 2School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA, 3School of Mechanical Engineering, University of Louisville School of Medicine, Louisville, KY

    *Purpose: The full potential of islet transplantation will only be realized by the development of tolerogenic strategies that obviate the need for maintenance immunosuppressants. We…
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