Am J Transplant, Volume 20, Suppl 3 Archives - Page 100 of 223 - ATC Abstracts

2020 American Transplant Congress
Successful Heart Utilization and Outcomes with Long-Distance Transport of Deceased Donor Hearts: One Large Organ Procurement Organization’s Five-Year Experience
D. Adorno, C. Wells, K. O'Connor
LifeCenter Northwest, Bellevue, WA
*Purpose: Long-distance transport of deceased donor hearts has been associated with reduced organ utilization rates and risk of inferior outcomes. One U.S. Organ Procurement Organization’s…
2020 American Transplant Congress
Suppressing Laminin Alpha5 Creates Tolerogenic Niches for Allograft Survival
L. Li¹, M. Shirkey¹, W. Piao¹, Y. Xiong¹, V. Saxena¹, T. Zhang¹, C. Paluskievicz¹, J. Zhao², R. Abdi², J. S. Bromberg¹
¹UMB, Baltimore, MD, ²Harvard University, Boston, MA
*Purpose: Laminin α5 (Lama5) regulates CD4 T cell migration and function. We hypothesized that stromal Lama5 regulates the structure of the lymph node (LN) microenvironment…
2020 American Transplant Congress
Interim Experience in a Phase 3 Prospective, Randomized, Multi-Center, Open-Label, Controlled Trial of Cellular Immunotherapy with MDR-101 for Induction of Immune Tolerance in Recipients of HLA-Matched, Living Donor Kidney Transplants
D. Kaufman¹, J. Piper², M. Stegall³, S. Akkina⁴, E. Marin⁵, A. Gaber⁶, Y. Qasi⁷, T. Srinivas⁸, D. Alonso⁹, A. Patel¹⁰, M. Laftavi¹¹, A. Shah¹², S. Collette¹³, E. Stites¹⁴, K. Chavin⁸, S. Crowley¹⁵
¹UW, Madison, WI, ²INOVA, Fairfax, VA, ³Mayo, Rochester, MN, ⁴LUMC, Chicago, IL, ⁵Yale, New Haven, CT, ⁶Houston Methodist, Houston, TX, ⁷USC, Los Angeles, CA, ⁸UH Cleveland, Cleveland, OH, ⁹Intermountain, Murray, UT, ¹⁰SBMC, Livingston, NJ, ¹¹UH Upstate, Syracuse, NY, ¹²TJU, Philadelphia, PA, ¹³CIUSSS, Montreal, QC, Canada, ¹⁴UCH, Denver, CO, ¹⁵Medeor, San Francisco, CA
*Purpose: The goals of tolerance in patients with kidney transplants (KTxp) are to eliminate the lifelong need for immunosuppressive drugs (IS) and to prevent graft…
2020 American Transplant Congress
Benefits of Normothermia Regional Perfusion (NRP), Hypothermic Machine Perfusion (HMP) and Short Cold Ischemia Time (CIT) for Kidney Transplants with Controlled Donation after Circulatory Death (cDCD)
E. Savoye¹, C. Legeai¹, J. Branchereau², S. Gay³, S. Drouin⁴, F. Gaudez⁵, B. Veber⁶, J. Venhard⁷, G. Cheisson⁸, T. Kerforne⁹, O. Bastien¹, C. Antoine¹
¹Agence de la Biomedecine, La Plaine Saint Denis, France, ²CHU Nantes, Nantes, France, ³CH Annecy, Annecy, France, ⁴CHU Pitié Salpetriere, Paris, France, ⁵CHU Saint Louis, Paris, France, ⁶CHU Rouen, Rouen, France, ⁷CHU Tours, Tours, France, ⁸CHU Kremlin-Bicetre, Kremlin-Bicetre, France, ⁹CHU Poitiers, Poitiers, France
*Purpose: cDCD are considered as extended criteria donors with poorer kidney transplant outcomes and high delayed graft function (DGF) rate. We built a French national…
2020 American Transplant Congress
The Living Donor Collective Pilot Evaluations of Living Kidney Donor Candidates at 10 Programs
B. Kasiske, M. Conboy, Y. Ahn, A. Israni, J. Snyder
SRTR, Minneapolis, MN
*Purpose: Much remains to learn regarding long-term effects of living organ donation on donors. Rare events are important, and long-term follow-up with appropriate contemporaneous controls…
2020 American Transplant Congress
Perioperative Opioid Avoidance in Liver Transplant Recipients: Significant Reduction in Opioid Use Through a Multidiscplinary, Multimodal Approach
H. Kutzler, R. Gannon, W. Nolan, L. Meisterling, M. Cech, D. Gleason, J. Uzl, C. Rochon, B. Maneckshana, O. Serrano, J. Riley, D. O'Sullivan, E. Urtasun-Sotil, M. Einstein, P. Sheiner
Hartford Hospital, Hartford, CT
*Purpose: Given the association between substance use disorder and risk of post-surgical opioid use disorder, we developed an opioid avoidance pathway (OAP) in adult liver…
2020 American Transplant Congress
Impact of Center Volume and MELD on Textbook Outcome Rates in Liver Transplantation
A. D. Schenk, J. L. Han, A. J. Logan, J. M. Sneddon, G. L. Brock, W. K. Washburn
Department of Surgery, Division of Transplantation, The Ohio State University Wexner Medical Center, Columbus, OH
*Purpose: Textbook outcome (TO) is a composite quality metric used in liver transplantation (LT) and defined as patient and graft survival > 1 year, length…
2020 American Transplant Congress
Kidney-Pancreas Transplant Survival after Pregnancy
S. Rao¹, L. Coscia², S. Constantinescu³, M. J. Moritz⁴
¹Medicine, University of Virginia Heath System, Charlottesville, VA, ²Transplant Pregnancy Registry International, Philadelphia, PA, ³Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, ⁴Surgery, Lehigh Valley Health Network, Allentown, PA
*Purpose: This study compared transplant survival after pregnancy in type 1 diabetic recipients (n=103) who received either kidney-pancreas (KP, n=61) or kidney alone (KA, n=42).*Methods:…
2020 American Transplant Congress
Tertiary Lymphoid Organs in Renal Chronic Allograft Rejection
K. Abou Daya, D. Zhao, K. Biery, M. Oberbarnscheidt
Starzl Transplantation Institute, Pittsburgh, PA
*Purpose: Chronic allograft rejection remains a major obstacle to long-term allograft survival. Tertiary lymphoid organs (TLOs) are ectopic lymphoid structures that arise in non-lymphoid tissues…
2020 American Transplant Congress
Addressing Critiques of the Proposed CMS Metric of Organ Procurement Organ Performance: More Data Isn’t Better
D. Goldberg¹, B. Doby², R. Lynch³
¹Medicine, University of Miami, Miami, FL, ²Johns Hopkins University, Baltimore, MD, ³Emory University, Atlanta, GA
*Purpose: CMS has proposed a rule change to re-define the OPO donation metric, using CDC inpatient death data to calculate: # of donors/1,000 inpatient deaths…