Am J Transplant, Volume 19, Suppl 3 Archives - Page 94 of 214 - ATC Abstracts

2019 American Transplant Congress
Targeted Epitope Mutagenesis as a Strategy to Decrease Xenoantibody Binding
J. Ladowski, G. Martens, Z. Wang, L. Reyes, M. Tector, J. Tector
University of Alabama-Birmingham, Birmingham, AL
*Purpose: Xenotransplantation, the use of genetically-modified pig organs for transplantation, has been limited by antibody-mediated rejection. The generation of a three-antigen knockout pig provided a…
2019 American Transplant Congress
Impact of Glomerulitis at 4-Month Biopsy on Long Term Kidney Allograft Outcomes
M. Whigham, G. Mour, M. Buras, S. Sukumaran Nair, A. Jaramillo, D. Ramon, R. Heilman
Mayo Clinic, Phoenix, AZ
*Purpose: Antibody mediated rejection (AMR) is diagnosed based on combination of elevated creatinine, histopathological findings defined as glomerulitis (g), and peritubular capillaritis (ptc), with or…
2019 American Transplant Congress
Hope Act Donors With Organs Recovered For Transplant: The First Two Years
W. A. Werbel, O. Kusemiju, B. Barnaba, M. Bowring, B. Doby, C. Kirby, R. Fernandez, Y. Eby, J. Miller, D. Brown, S. Seaman, D. Ostrander, A. Tobian, D. Segev, C. M. Durand
Johns Hopkins University, Baltimore, MD
*Purpose: The HOPE Act expands the potential deceased donor pool to include HIV+ donors (HIV D+) and donors with false-positive (FP) HIV screens. The objective…
2019 American Transplant Congress
Simultaneous Robotic Kidney Transplantation and Bariatric Surgery for Morbidly Obese Patients with End-Stage Renal Failure
P. West-Thielke, K. A. Tulla, O. T. Okoye, J. A. Almario Alvarez, M. Spaggiari, I. G. Tzvetanov, E. Benedetti
University of Illinois at Chicago, Chicago, IL
*Purpose: The purpose of this study is to evaluate the safety and efficacy of simultaneous robotic assisted kidney transplant and robotic assisted sleeve in obese…
2019 American Transplant Congress
Ex-Vivo Perfusion Mediated Delivery of Rituximab to Clear Latent Epstein-Barr Virus
T. Ku, M. Cypel, R. V. Ribeiro, V. H. Ferreira, D. Kumar, A. Humar
UHN, Toronto, ON, Canada
*Purpose: Post-transplant lymphoproliferative disorder (PTLD) can manifest as a B-cell malignancy associated with Epstein-Barr virus (EBV) infection. Risk of PTLD is greatest in EBV D+/R-…
2019 American Transplant Congress
ZFYVE21 is a Novel Complement-Induced Rab5 Effector Protein Mediating Cardiac Allograft Vasculopathy
D. Jane-wit¹, C. Fang¹, L. Liu¹, L. Qin¹, G. Guangxin Li¹, P. Nigrovic², G. Tellides³, J. Pober⁴
¹Dept of Cardiology, Yale University School of Medicine, New Haven, CT, ²Dept of Rheumatology, Immunology, and Allergy, Harvard University, Boston, MA, ³Dept of Surgery, Yale University School of Medicine, New Haven, CT, ⁴Dept of Immunobiology, Yale University School of Medicine, New Haven, CT
*Purpose: Complement promotes vascular inflammation in transplant organ rejection, a process leading to cardiac allograft vasculopathy. In this study, we identify a new Rab5 effector…
2019 American Transplant Congress
Tolerance Induction with Hematopoietic Stem Cells in Kidney Transplantations
K. Lee, J. Park, Y. Chung, S. Kim
Department of Surgery, Samsung Medical Center, Seoul, Korea, Republic of
*Purpose: Tolerance induction is considered to be the final goal in the field of organ transplantation. We have performed combined bone marrow and kidney transplantation…
2019 American Transplant Congress
Impact of Preoperative Rifaximin Use on Reducing Graft Injury in Liver Transplantation: A Propensity Matched Analysis
T. Ito, K. Nakamura, S. Kageyama, H. Hirao, K. Kadono, J. Aziz, J. DiNorcia, V. G. Agopian, H. Yersiz, D. G. Farmer, R. W. Busuttil, J. Kupiec-Weglinski, F. M. Kaldas
Department of Surgery, The Dumont-UCLA Transplant Center, Los Angeles, CA
*Purpose: Intestinal microbiota are thought to play an important role in affecting the multifactorial and complex mechanisms of hepatic ischemia reperfusion injury (IRI) after liver…
2019 American Transplant Congress
Belatacept Based Simultaneous Calcineurin Inhibitor Avoidance/Early Corticosteroid Withdrawal is Associated with Low New Onset Diabetes Risk
A. R. Shields¹, P. West-Thielke², E. S. Woodle¹, D. B. Kaufman³, J. Lipscomb⁴, J. P. Leone⁵, A. Wiseman⁶, E. King⁴, A. J. Matas⁷, R. R. Alloway for the BEST Study Group⁴
¹Transplant Surgery, U of Cincinnati, Cincinnati, OH, ²UIC, Chicago, IL, ³Transplant Surgery, U of Wisconsin, Madison, WI, ⁴U of Cincinnati, Cincinnati, OH, ⁵Tampa General, Tampa, FL, ⁶U of Colorado, Denver, CO, ⁷U Minnesota, Minneapolis, MN
*Purpose: Calcineurin inhibitor (CNI) and/or corticosteroid (CCS) therapy are associated with significant risk of new onset diabetes after transplantation (NODAT). An important consideration for simultaneous…
2019 American Transplant Congress
Differences in Wait Time, Graft Quality and Outcome for Pediatric Kidney Recipients in the Post-Kidney Allocation System Era
P. Singer, K. Eng, L. Castellanos Reyes, C. Sethna, L. Teperman, E. Grodstein
Northwell Health, Manhasset, NY
*Purpose: Though a purpose of the kidney allocation system (KAS) enacted in 2014 was to prioritize the transplantation of highly sensitized recipients, we explored the…