Am J Transplant, Volume 19, Suppl 3 Archives - Page 94 of 214 - ATC Abstracts

2019 American Transplant Congress
Donor-Specific Tregs Prolong Peripheral Chimerism in Baboons Receiving GalTKO hCD47-tg Porcine Peripheral Blood Stem Cells
N. P. Llore¹, J. Stern¹, G. Pierre¹, E. Lopes¹, D. Ekanayake-Alper¹, P. Alonso-Guallart¹, K. Bruestle¹, H. Sakai¹, D. Ayares², M. Lorber², R. Hawley¹, D. H. Sachs¹, M. Sykes¹, A. D. Griesemer¹
¹Columbia Center for Translational Immunology, New York, NY, ²United Therapeutics, Silver Springs, MD
*Purpose: We have previously evaluated the ability of transplantation of polyclonal expanded recipient T regulatory cells to prolong xenogeneic chimerism and skin grafts after transplantation…
2019 American Transplant Congress
The Graft and Patient Survival of Kidney Transplantation According to Ethnicity in US Kidney Transplant Recipients
H. Shin¹, Y. Kim¹, Y. Jung¹, H. Rim¹, A. Chandraker²
¹Internal Medicine, Kosin University College of Medicine, Gospel Hospital, Busan, Korea, Republic of, ²Internal Medicine, Harvard Medical School Brigham & Women's Hospital, Boston, MA
*Purpose: African American kidney transplant recipients experience disproportionately high rates of graft loss. The aim of this analysis was to use a UNOS data set…
2019 American Transplant Congress
Long-Term Outcomes Following Uncontrolled Donation after Cardiac Death Kidney Transplantation: Opportunity for Increasing Donor Pool?
R. A. Choudhury, K. Prins, D. Yoeli, H. B. Moore, T. L. Nydam
Transplant Surgery, University of Colorado, Aurora, CO
*Purpose: Uncontrolled donation after cardiac death (uDCD) represents an underutilized source of donors in the United States. However, controversy surrounding the long-term durability of uDCD…
2019 American Transplant Congress
IgG4 Subclass Class 2 Donor Specific Antibody (DSA) is Associated with Subclinical Rejection in Stable Pediatric Liver Transplant (LT) Recipients with Normal Liver Tests
A. Jackson¹, S. Kanaparthi², B. Burrell³, D. Lucas⁴, R. Vega⁴, A. J. Demetris⁵, S. Feng⁶
¹Surgery, Duke University, Durham, NC, ²The Immune Tolerance Network, Bethesda, MD, ³Immune Tolerance Network, Bethesda, MD, ⁴Medicine, Johns Hopkins University, Baltimore, MD, ⁵Pathology, University of Pittsburgh, Pittsburgh, PA, ⁶Surgery, University of California San Francisco, San Francisco, CA
*Purpose: DSA is a known biomarker of allograft rejection, yet injury phenotype and potential differ across organs. Among pediatric LT recipients entering iWITH (NCT01638559), an…
2019 American Transplant Congress
Impact of Cytomegalovirus on the Immune System of Healthy Humans
W. Zhang, J. Robertson, G. Karadkhele, B. Johnson, C. Larsen
Emory Transplant Center, Emory University, Atlanta, GA
*Purpose: CMV is a frequent pathogen after transplantation. 2/3 of recipients harbor latent CMV and are at moderate risk. CMV- recipients divide into high or…
2019 American Transplant Congress
Ligation Of Hla Class Il Molecules Disrupts Endothelial Barrier Through Src-dependent Ve-cadherin Destabilization
F. Li¹, R. A. Sosa¹, N. M. Valenzuela¹, E. Rozengurt², E. F. Reed¹
¹Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA, ²Digestive Diseases Research Center, University of California, Los Angeles, Los Angeles, CA
*Purpose: Microvascular inflammation, vascular permeability, and accumulation of intravascular mononuclear cells are characteristics of acute and chronic antibody-mediated rejection. Vascular endothelial cadherin (VE-Cadherin) is a…
2019 American Transplant Congress
Incidence and Risk of Allograft Rejection after Cardiac Transplantation in Left Ventricular Assist Device Patients
R. C. Patel¹, L. B. Cooper², S. D. Barnett², R. T. Cole², M. A. Psotka², A. Cochrane², S. Sinha², L. J. Bogar², S. S. Desai², P. Shah²
¹Virginia Commonwealth University School of Medicine, Inova Fairfax Hospital, Falls Church, VA, ²Department of Heart Failure and Transplant, Inova Heart and Vascular Institute, Falls Church, VA
*Purpose: Left ventricular assist devices (LVAD) are made of biomaterials that have been shown to cause allosensitization. Single center studies have suggested that patients bridged…
2019 American Transplant Congress
Early Steroid Withdrawal in African American Deceased Donor Renal Transplant Recipients with Alemtuzumab Induction: Is Graft Loss on the Horizon?
R. Lynn, B. Ravichandran, T. Sparkes, A. Haririan, J. Bromberg, J. Casale
University of Maryland Medical Center, Baltimore, MD
*Purpose: The safety of early steroid withdrawal (ESW) in African American (AA) deceased donor renal transplant recipients (DDRTs) is unclear. This study assessed the impact…
2019 American Transplant Congress
The Evolution of Body Mass Index after Kidney Transplantation in Recipients with a Previous Laparoscopic Sleeve Gastrectomy
G. Chan, F. Briere
Universite de Montreal, Hopital Maisonneuve-Rosemont, Montreal, QC, Canada
*Purpose: Bariatric surgery is one of the most common operations. Laparoscopic sleeve gastrectomy (LSG) has been reported to prepare candidates for listing. However, weight gain…
2019 American Transplant Congress
Transplant Center Practices Are the Primary Drivers of United States Donation after Circulatory Death Liver Transplantation
L. Beal¹, D. T. Nguyen², T. Menser³, S. Zajac¹, E. A. Graviss², M. J. Hobeika¹
¹Department of Surgery, Houston Methodist Hospital, Houston, TX, ²Department of Pathology and Genomic Medicine, Houston Methodist Research Institute, Houston, TX, ³Center for Outcomes Research, Houston Methodist Research Institute, Houston, TX
*Purpose: We hypothesize that a few high-utilization donation after circulatory death (DCD) liver centers are the primary drivers of the dissimilar rates of DCD liver…