2019 American Transplant Congress
Correlates of Significant Weight Changes Following Pancreas Alone Transplantation
University of Wisconsin, Madison, WI
*Purpose: Significant weight change is defined as unintentional weight gain of ≥ 7% of body weight or unintentional weight loss of > 5% in one…2019 American Transplant Congress
Evaluating the Predictive Utility of the Stanford Integrated Psychosocial Assessment for Transplantation (SIPAT) for Post-Transplant Outcomes in Moderate to High-Risk Liver Transplant Candidates
Hartford Hospital, Hartford, CT
*Purpose: Previous studies suggest the Stanford Integrated Psychosocial Assessment for Transplantation (SIPAT) is predictive of post-transplant outcomes in multiorgan transplant candidates. We aim to determine…2019 American Transplant Congress
The Impact of Acute Rejection in Heart Transplantation on Post-Transplant Malignancy
*Purpose: Compared with the general population, an increased incidence of skin cancers and lymphomas have been shown in orthotopic heart transplant (OHT) recipients. However, the…2019 American Transplant Congress
First Report and Mechanistic Analysis of Chronic GVHD after Solid Organ Transplantation
Georgetown University Hospital, Washington, DC
*Purpose: Chronic graft-versus-host disease (cGVHD) occurs late after bone marrow transplantation and is associated with a characteristic lichenoid rash (cutaneous sclerosis) and effects on multiple…2019 American Transplant Congress
Specific Donor/Recipient HLA Disparities are Associated with Better Long-Term Kidney Allograft Survival among 4-, 5-, and 6-HLA (A/B/DR)-Mismatched Pairs
University of Toledo, Toledo, OH
*Purpose: The vast majority of deceased donor kidneys are allocated without any consideration for the HLA disparities, which may improve or worsen the survival the…2019 American Transplant Congress
Vimentin Inhibition Improves Post-Transplant Survival in a Mouse Renal Transplant Model
*Purpose: Most renal transplants ultimately fail secondary to chronic allograft nephropathy (CAN). The development of Epithelial to Mesenchymal Transition (EMT) in renal tubular epithelial cells…2019 American Transplant Congress
The High Burden of Vaccine Preventable Infections Following Pediatric Solid Organ Transplant
*Purpose: Pediatric transplant recipients are at risk for vaccine preventable infections due to immunosuppression, suboptimal response to vaccines before and after transplant, and potential under-immunization…2019 American Transplant Congress
Variable Glycosylations of Anti-HLA Antibodies Detected with Single Antigen Beads in Kidney Transplant Recipients
*Purpose: Differential glycosylation of Immunoglobulin G (IgG) is known to affect its effector functions by modulating interactions with its binding partners, such as C1q or…2019 American Transplant Congress
Depleting Laminin α5 in Lymph Node Stromal Cells Promotes Transplant Tolerance
Surgery, U. Maryland, Baltimore, Baltimore, MD
*Purpose: Expression of stromal laminin α5β1γ1 (511) in lymph nodes (LN) is associated with immunity, while laminin α4β1γ1 (411) is associated with tolerance. The laminins…2019 American Transplant Congress
Comparative Use of Single mTOR vs Dual mTOR/PI3K Inhibition in Regulatory T Cell Expansion for Clinical Application in Transplantation
University of Kentucky, Lexington, KY
*Purpose: Experimental and pre-clinical evidence suggest that adoptive transfer of regulatory T cells (Tregs) could be an appropriate therapeutic strategy to induce tolerance and improve…
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