ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Induction Immunosuppression Practices in Liver Transplantation are Variable and Predict Post-Transplant Survival

    T. Bittermann1, R. Hubbard2, J. Lewis1, D. Goldberg1

    1Gastroenterology, University of Pennsylvania, Philadelphia, PA, 2University of Pennsylvania, Philadelphia, PA

    *Purpose: Unlike in other solid organ transplants, the benefits of induction immunosuppression prior to liver transplantation (LT) remain uncertain. The objective of this study was…
  • 2019 American Transplant Congress

    Rcor1 and Regulation of Foxp3+ T-Regulatory Cells In Vitro and In Vivo

    Y. Xiong, L. Wang, R. Han, W. W. Hancock

    Children's Hospital of Philadelphia, Philadelphia, PA

    *Purpose: While Foxp3+ T-regulatory (Treg) cells are well established as central players in regulation of allograft acceptance and tolerance, the contributions of several types of…
  • 2019 American Transplant Congress

    The Role of Non-Traditional Environmental Factors in Long-Term Outcomes of Liver Transplantation

    J. Buggs1, D. Patino2, B. Evans1, C. Anderson1, C. Delfavero1, E. Rogers1, A. Alsina1, A. Kumar3

    1Tampa General Hospital, Tampa, FL, 2University of Tampa, Tampa, FL, 3University of South Florida, Tampa, FL

    *Purpose: The purpose of this research project was to evaluate the role of non-traditional subjective environmental factors in long-term outcomes of liver transplantation.*Methods: We conducted…
  • 2019 American Transplant Congress

    The Impact of Race on Metabolic, Graft and Patient Outcomes after Pancreatic Transplantation

    V. S. Rohan, S. N. Nadig, J. Mcgillicuddy, V. Rao, D. Dubay, K. Soliman, P. Baliga, D. Taber

    Transplant Surgery, Medical University of South Carolina, Charleston, SC

    *Purpose: Health disparities in African-Americans (AAs) are well-documented in kidney transplantation. There is a paucity of data regarding effect race in pancreas transplant (PTX) outcomes.*Methods:…
  • 2019 American Transplant Congress

    Cost-Effectiveness Analysis of Renal Replacement Therapy Strategies in Haiti

    J. S. Pyda1, L. James2, J. J. Kim2, K. Khwaja1, M. Shrime3

    1Department of Surgery, Beth Israel Deaconess Medical Center, Boston, MA, 2Center for Health Decision Science, Harvard T.H. Chan School of Public Health, Boston, MA, 3Program in Global Surgery and Social Change, Harvard Medical School, Boston, MA

    *Purpose: Kidney transplantation (KT) is the optimal renal replacement therapy (RRT) for patients with end-stage renal disease (ESRD) in high-income countries (HICs) conferring the highest…
  • 2019 American Transplant Congress

    Anti-Xa Level Monitoring for Treatment Dose Enoxaparin in Liver/Intestine Transplant Recipients

    J. Sullivan, J. Jebrock, J. Revollo, M. Perez, J. Garcia, T. Beduschi

    Jackson Memorial Hospital, Miami, FL

    *Purpose: Evaluate the use of anti-Xa levels in therapeutic enoxaparin dosing in liver/intestine transplant recipients.*Methods: A single-center retrospective chart review was conducted on liver/intestine transplant…
  • 2019 American Transplant Congress

    A Multi National Study Ofkidney Transplantation In Inmates

    Y. Qazi, A. Mahajan, D. Bahl, F. Jan

    Keck Medical Center at USC, Los Angeles, CA

    *Purpose: Over 10 million inmates exist in prison worldwide, with United States accounting for over fifth of this population. The number of inmates with ESRD…
  • 2019 American Transplant Congress

    Notch1 Signaling Protects Liver Grafts from Ischemia Reperfusion Injury: From Mouse to Human

    K. Kadono, S. Kageyama, H. Hirao, K. Nakamura, T. Ito, K. J. Dery, D. Oncel, B. Ke, F. M. Kaldas, R. W. Busuttil, J. W. Kupiec‐Weglinski

    Surgery, Dumont-UCLA Transplant Center, Los Angeles, CA

    *Purpose: The clinical relevance and tissue-specific role of Notch1 activation, a highly conserved transmembrane receptor involved in cell fate decision, proliferation and regeneration, in orthotopic…
  • 2019 American Transplant Congress

    Donor-Derived Cell-Free DNA for Surveillance in Simultaneous Pancreas and Kidney Transplant Recipients, Can We Extrapolate from Kidney Transplant Alone?

    O. K. Olaitan1, S. Loeb1, E. Hetterman2, V. Peev1, S. Saltzberg1, M. Hertl1, S. Dholakia2

    1Rush University Medical Center, Chicago, IL, 2CareDx, Brisbane, CA

    *Purpose: Assessment and identification of early organ injury in Simultaneous Pancreas and Kidney (SPK) patients has clear clinical utility. This analysis was performed to establish…
  • 2019 American Transplant Congress

    Blockade of IL-1β and TNF-α Does Not Significantly Pose Risk or Affect Outcomes in Patients Infused with Microbial-Positive Autologous Islet Preparations

    K. Kumano1, C. Darden2, S. Vasu1, M. Lawrence1, B. Naziruddin3, A. Gupta3, E. Beecherl3, N. Onaca3

    1Baylor Scott and White Research Institute, Dallas, TX, 2Baylor University, Waco, TX, 3Baylor Simmons Transplant Institute, Dallas, TX

    *Purpose: We recently demonstrated that the combined use of anakinra (IL-1β blocker) and etanercept (TNF-α blocker) improved outcomes of islet autotransplantation after total pancreatectomy (TPIAT).…
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