ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    The Impact of Removing DSA as a First Unit of Lung Allocation: Preliminary Results

    R. R. Lehman1, K. Uccellini2, M. Skeans3, M. Valapour3, E. D. Lease4, R. Daly5, K. M. Chan6

    1Research, United Network for Organ Sharing, Richmond, VA, 2Policy, United Network for Organ Sharing, Richmond, VA, 3SRTR, Minneapolis, MN, 4Univ of Washington, Seattle, WA, 5Mayo Clinic, Rochester, MN, 6Univ of Michigan, Ann Arbor, MI

    *Purpose: In an emergency action on November 24, 2017 the Organ Procurement and Transplantation Network (OPTN) altered US lung allocation policy by replacing the donor…
  • 2019 American Transplant Congress

    Circulating Mirnas Regulate Gene Expression In Kidney Tissue During Transplant Glomerulopathy

    C. Kuscu1, V. Sai Bontha1, C. Kuscu1, D. Maluf1, A. Bajwa1, J. Eason1, V. Mas1, E. Akalin2

    1UTHSC, Memphis, TN, 2Albert Einstein College of Medicine, NYC, NY

    *Purpose: Post-transplant glomerular disease includes membranous glomerulopathy (MG), secondary or primary focal segmental glomerulosclerosis (FSGS). Furthermore, at post transplant, TG is an important cause of…
  • 2019 American Transplant Congress

    Predictors and Outcomes of Acute Graft-versus-Host Disease after Liver Transplant

    A. Caines1, S. Nagai2, R. Salgia1

    1Gastroenterology and Hepatology, Henry Ford Health System, Detroit, MI, 2Transplant Surgery, Henry Ford Health System, Detroit, MI

    *Purpose: Graft-versus-Host Disease (GVHD) is a rare complication of liver transplant (LT) that has an estimated incidence of 0.1%-2% per year and is associated with…
  • 2019 American Transplant Congress

    Evaluation of Medication Burden in Kidney Transplant Recipients at Time of Index Hospitalization

    J. Hardcopf1, H. Meadows1, T. Harrison1, H. Corbo1, B. O'brien1, J. N. Fleming1, C. Perez1, N. Patel1, N. Pilch1, P. K. Baliga2, D. DuBay2, D. Taber1

    1Department of Pharmacy Services, Medical University of South Carolina, Charleston, SC, 2Division of Transplant Surgery, Department of Surgery, Medical University of South Carolina, Charleston, SC

    *Purpose: This study will assess whether a higher number of medication changes from pre- to post-transplant lead to worse clinical outcomes and higher healthcare utilization…
  • 2019 American Transplant Congress

    Targeted Proteomic Analysis Detects Acute T Cell-Mediated Kidney Allograft Rejection in Belatacept-Treated Patients

    M. van der Zwan, D. A. Hesselink, M. C. Clahsen-van Groningen, C. C. Baan

    Erasmus MC, Rotterdam, Netherlands

    *Purpose: There is an unmet need for reliable minimally-invasive diagnostic biomarkers for immunological allograft monitoring and detection of acute kidney transplant rejection. Here, targeted proteomic…
  • 2019 American Transplant Congress

    Utilizing Ides To Eliminate Residual Antibodies Targeting Xenografts

    C. Rickert, K. Lee, N. Tanimine, J. Lei, A. Cuenca, N. Feeney, K. Deng, H. Yeh, J. F. Markmann

    Massachusetts General Hospital, Boston, MA

    *Purpose: A significant hinderance to the successful use of xenotransplantation has been the presence of preformed antibodies against the donor antigens, known as xenoantigens. Using…
  • 2019 American Transplant Congress

    Comparison of Minimal Incision Kidney Transplantation with Conventional Incision Kidney Transplantation: Interim Report of a Randomized Controlled Trial

    T. Lin, T. Song, Y. Jiang, Y. Fan, X. Wang, Z. Huang, J. Liu, Z. Wang

    Organ Transplantation Center, Urology Department, Urology Research Institute, WestChina Hospital, Sichuan University, Chengdu, China

    *Purpose: Minimally invasive surgery is rarely applied in kidney transplantation. Few studies have mentioned small incision kidney transplantation, while the incision length is still about…
  • 2019 American Transplant Congress

    Expansion of Regulatory T and B Cells in Swine Rendered Tolerant of Allogeneic Vascularized Composite Allografts via Mixed Chimerism

    G. Saviane1, A. Lellouch1, A. Andrews1, L. Lantieri2, M. Randolph1, G. Benichou1, C. Cetrulo Jr1

    1Center for Transplantation Sciences, Division of Plastic Surgery, Boston, MA, USA, Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA, Boston, MA, 2European Georges Pompidou Hospital, University of Paris, Department of Plastic Surgery, Paris, France

    *Purpose: Prevention of acute rejection of vascularized composite allografts (VCAs) requires ongoing systemic immunosuppression, which subject patients to infectious, metabolic, reno-vascular and neoplastic complications. It…
  • 2019 American Transplant Congress

    6-Minute Walk Testing in Patients on the Kidney Transplant Waitlist

    X. S. Cheng1, J. Lee2, K. V. Discipulo1, J. Myers3, J. C. Tan1

    1Nephrology, Stanford University, Palo Alto, CA, 2Kidney Transplant, Stanford Hospital, Palo Alto, CA, 3Cardiology, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA

    *Purpose: Poor physical function in kidney transplant candidates is associated with frailty, sub-optimal transplant outcomes, and higher health care utilization. We need an instrument to…
  • 2019 American Transplant Congress

    Digital Imaging Software vs. the “Eyeball” Method in Quantifying Steatosis in a Liver Biopsy

    J. Long1, J. Motter1, S. Besharati1, S. Jerman2, R. Anders1, A. Ortiz2, D. Bowman2, T. Dunn3, D. Lee4, A. Massie1, R. Barth5, B. Philosophe1

    1Johns Hopkins, Baltimore, MD, 2Indica Labs, Corrales, NM, 3UPenn, Philadelphia, PA, 4Mayo Clinic, Jacksonville, FL, 5University of MD, Baltimore, MD

    *Purpose: The use of steatotic livers is controversial, but may represent an underutilized resource to increase the donor pool. Although
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