ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Mechanical Irritation in Vascularized Tissue Allotransplantation Triggers Localized Skin Rejection

    F. Messner, A. Fischer, E. Runggaldier, S. Eiter, B. Zelger, B. Zelger, S. Sprung, D. Öfner, S. Schneeberger, T. Hautz

    Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Austria

    *Purpose: “Atypical” forms of skin rejection have been described in some hand transplanted patients mainly manifesting on the palm including dryness, scaling and thickening of…
  • 2019 American Transplant Congress

    Immunosuppression after Organ Transplantation Does Not Enhance Patency of Cold-Stored Vein Allografts for Critical Limb Ischemia -Single Centre Experience

    J. Chlupac, T. Marada, R. Novotny, K. Lipar, L. Janousek, J. Fronek

    Transplant Surgery Department, Institute for Clinical and Experimental Medicine, Prague, Czech Republic

    *Purpose: Sub-inguinal bypass with cold-stored saphenous vein allograft is a last option treatment for extensive peripheral arterial occlusive disease with absent autologous vein. The aim…
  • 2019 American Transplant Congress

    Randomized Controlled Trial Of Spironolactone Effect In Kidney Transplant Recipients Of Living Donors

    N. A. Bobadilla1, L. E. Morales-Buenrostro1, J. A. Ortega-Trejo1, R. Perez-Villalva1, L. Marino1, Y. González-Bobadilla1, H. Juarez1, F. Zamora-Mejía1, N. Gonzalez1, R. Espinoza2, J. Barrera-Chimal3

    1Nephrology, INCMNSZ, Mexico City, Mexico, 2Nephrology, Centro Médico Nacional Siglo XXI, Mexico City, Mexico, 3Molecular Physiology Unit, Instituto de Investigaciones Biomédicas, UNAM, Mexico City, Mexico

    *Purpose: Mineralocorticoid receptor antagonism prevents acute kidney injury induced by ischemia/reperfusion in rodent and pig preclinical models. In a pilot study, we showed that spironolactone…
  • 2019 American Transplant Congress

    CD38 Inhibition: A Novel Target for Hepatic Ischemia Reperfusion Injury

    C. Akateh1, B. F. Reader1, Y. Lee1, J. Kim1, K. Maynard1, K. W. Washburn1, J. L. Zweier2, B. A. Whitson1, S. M. Black1

    1Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, 2The Ohio State University Wexner Medical Center, Columbus, OH

    *Purpose: Ischemia/reperfusion injury (IRI) is a major source of injury during many surgical procedures on the liver, and severe IRI can lead to post-hepatectomy liver…
  • 2019 American Transplant Congress

    Improvement of the Outcome of Clinical Islet Transplantation Depending on the Era in Japan

    Y. Akashi1, T. Kenmochi2, T. Ito3, K. Kurihara2, N. Aida2, A. Kawai2, M. Hayashi4, K. Kouketsu4

    1Faculty of Nursing, School of Health Sciences, Fujita Health University, Toyoake, Japan, 2Department of Transplantation and Regenerative Medicine, Fujita Health University, Toyoake, Japan, 31 Department of Transplantation and Regenerative Medicine,, Fujita Health University, Toyoake, Japan, 4Transplant medical support office, Fujita Health University Hospital, Toyoake, Japan

    *Purpose: Islet transplantation (ITX) is an ideal treatment for type 1 diabetic patients. In this paper, we compared the outcome of ITX depending on Era…
  • 2019 American Transplant Congress

    Evaluating Adherence to Immunosuppressive Drugs through Trackyourmed® an Innovative Qr Code-Scanner App in Renal Transplantation: Preliminary Results from i-COM Trial

    E. Melilli1, M. Meneghini1, N. Montero1, A. Coloma1, I. Revuelta2, F. Moreso3, V. Torregrosa2, J. Grinyo1, O. Bestard1

    1Renal Transplant Unit, Bellvitge University Hospital, L'Hospitalet de Llobregat, Spain, 2Renal Transplant Unit, Hospital Clinic, Barcelona, Spain, 3Renal Transplant Unit, Vall D'Hebron Hospital, Barcelona, Spain

    *Purpose: Low adherence to chronic immunosuppressive (IS) drugs has been recognized as a major cause of premature graft loss. Although erratic trough blood IS levels…
  • 2019 American Transplant Congress

    Characterization of HLA Antibodies by C3d Assay and IgG Subclasses in Sensitized Kidney Transplant Patients

    A. Casillas-Abundis, J. M. Arreola-Guerra, J. Alberu, M. I. Solis-G, L. Llorente, J. Granados, M. Vilatoba, R. Cruz-Martinez, L. Morales-Buenrostro, A. G. Contreras

    Instituto Nacional de Ciencias Medicas y Nutricion SZ, Mexico City, Mexico

    *Purpose: To determine the detection rate of IgG subclasses (IgGsc) and C3d-binding HLA-antibodies (abs) in a cohort of highly sensitized kidney transplant patients.*Methods: We evaluated,…
  • 2019 American Transplant Congress

    Non-Invasive Monitoring of the Kidney Allograft

    S. Bontha1, G. Darville1, C. Kuscu1, C. Kuscu2, A. Bajwa1, J. Eason3, D. Maluf4, V. Mas5

    1Surgery, UTHSC, Memphis, TN, 2Surgery, UTHSC, memphis, TN, 3Surgery, Director of Transplant Institute - UTHSC, Memphis, TN, 4UTHSC, Memphis, TN, 5Surgery, Director of Transplant Research Institute, Memphis, TN

    *Purpose: A major issue in kidney transplantation is the lack of validated non-invasive biomarkers for monitoring graft function, current biochemical markers (i.e., creatinine) have poor…
  • 2019 American Transplant Congress

    Validation of Gene Expression Signatures Associated with Antibody-Mediated Rejection (ABMR) in Renal Allograft Biopsies (Bx) of HLA-Sensitized Patients

    H. Zhang1, C. C. Nast2, N. Ammerman3, A. A. Vo3, S. C. Jordan3, M. Toyoda1

    1Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA, 2Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, 3Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA

    *Purpose: "Thoroughly validated gene transcripts” in renal Bx was adopted as one of the criteria for ABMR diagnosis in the latest Banff classification. Previously, we…
  • 2019 American Transplant Congress

    Predicting Kidney Discards with Donor Admission Text

    A. Placona, C. Martinez, B. Carrico

    United Network for Organ Sharing, Richmond, VA

    *Purpose: Kidney discard rates have increased in part due to technological advancements and deceased donor policy updates that allow for recovery of organs at increased…
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