Am J Transplant, Volume 19, Suppl 3 Archives - Page 83 of 214 - ATC Abstracts

2019 American Transplant Congress
Expansion of Regulatory T and B Cells in Swine Rendered Tolerant of Allogeneic Vascularized Composite Allografts via Mixed Chimerism
G. Saviane¹, A. Lellouch¹, A. Andrews¹, L. Lantieri², M. Randolph¹, G. Benichou¹, C. Cetrulo Jr¹
¹Center for Transplantation Sciences, Division of Plastic Surgery, Boston, MA, USA, Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA, Boston, MA, ²European Georges Pompidou Hospital, University of Paris, Department of Plastic Surgery, Paris, France
*Purpose: Prevention of acute rejection of vascularized composite allografts (VCAs) requires ongoing systemic immunosuppression, which subject patients to infectious, metabolic, reno-vascular and neoplastic complications. It…
2019 American Transplant Congress
6-Minute Walk Testing in Patients on the Kidney Transplant Waitlist
X. S. Cheng¹, J. Lee², K. V. Discipulo¹, J. Myers³, J. C. Tan¹
¹Nephrology, Stanford University, Palo Alto, CA, ²Kidney Transplant, Stanford Hospital, Palo Alto, CA, ³Cardiology, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA
*Purpose: Poor physical function in kidney transplant candidates is associated with frailty, sub-optimal transplant outcomes, and higher health care utilization. We need an instrument to…
2019 American Transplant Congress
Digital Imaging Software vs. the “Eyeball” Method in Quantifying Steatosis in a Liver Biopsy
J. Long¹, J. Motter¹, S. Besharati¹, S. Jerman², R. Anders¹, A. Ortiz², D. Bowman², T. Dunn³, D. Lee⁴, A. Massie¹, R. Barth⁵, B. Philosophe¹
¹Johns Hopkins, Baltimore, MD, ²Indica Labs, Corrales, NM, ³UPenn, Philadelphia, PA, ⁴Mayo Clinic, Jacksonville, FL, ⁵University of MD, Baltimore, MD
*Purpose: The use of steatotic livers is controversial, but may represent an underutilized resource to increase the donor pool. Although
2019 American Transplant Congress
Wide Geographic Variability in the Proportion of Donors with Cardiac Death – Lost Opportunities for Organ Donation?
E. M. Sonnenberg¹, D. S. Goldberg², J. Y. Hsu³, P. P. Reese², P. L. Abt¹
¹Department of Surgery, University of Pennsylvania, Philadelphia, PA, ²Department of Medicine, University of Pennsylvania, Philadelphia, PA, ³Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA
*Purpose: Donation after cardiac death (DCD) donors are largely not considered by organ procurement organization (OPO) metrics, as DCD donors are only counted in donor…
2019 American Transplant Congress
Role of NF-kB in Release of Isletokines via Exosomes in Response to Islet Stress
P. Saravanan¹, M. Kanak¹, J. Kalivarathan¹, M. Lawrence², M. Levy¹, B. Naziruddin³
¹Department of Surgery, Virginia Commonwealth University, VCU Health, Richmond, VA, ²Islet Cell Lab, Baylor Scott and White Research Institute, Dallas, TX, ³Simmons Transplant Institute, Baylor Scott and White Medical Center, Dallas, TX
*Purpose: Human islets are exposed to a range of inflammatory stimuli upon transplantation that leads to poor graft survival. Identifying the various signaling events may…
2019 American Transplant Congress
Success in Lung Transplantation Outcomes after Receiving a Standardized Desensitization Therapy
S. Ganesh¹, C. L. Prohaska², C. Mares², M. J. Everly³
¹Medicine, Keck Medical Center at the University of Southern California, Los Angeles, CA, ²BioMatrix, Weston, FL, ³Terasaki Research Institute, Los Angeles, CA
*Purpose: With a goal to develop a safe, effective, and consistent approach to desensitization therapy using IVIg in lung transplant (LuT), we instituted a standard…
2019 American Transplant Congress
Pancreata From Donors With Renal Insufficiency: Viable For Transplant?
X. Luo¹, J. Garonzik Wang², M. B. Doyle¹, A. Khan¹, T. Alhamad³, W. C. Chapman¹, A. Massie², D. Segev², J. R. Wellen¹
¹Section of Abdominal Transplant Surgery, Washington University School of Medicine, St. Louis, MO, ²Department of Surgery, Johns Hopkins University, Baltimore, MD, ³Division of Nephrology, Washington University School of Medicine, St. Louis, MO
*Purpose: Pancreata are declined for transplantation for a multitude of reasons. Some of those reasons are organ edema as well as the potential for ischemic…
2019 American Transplant Congress
The Effect Of Exclusive Virtual Crossmatch To Allocate Deceased Donor Kidney Transplant On Cold Ischemia Time And Acute Rejection
E. Abuhelaiqa¹, M. Alkadi¹, S. Thappy¹, S. Saleh², J. Mahmoud³, M. Jarman³, O. Fituri¹, M. Elkhalifa⁴, J. Wadström³, H. Al-Malki¹
¹Medicine-Nephrology, Hamad Medical Corporation, Doha, Qatar, ²Histocompatibility & Immunogenetics Laboratory,, Hamad Medical Corporation, Doha, Qatar, ³Surgery-Transplant, Hamad Medical Corporation, Doha, Qatar, ⁴Histocompatibility & Immunogenetics Laboratory, Hamad Medical Corporation, Doha, Qatar
*Purpose: Virtual crossmatch (VXM) using Luminex single antigen bead has significantly improved prediction of an actual negative crossmatch. A negative crossmatch is typically required for…
2019 American Transplant Congress
Presence of DSA Class 2 is Associated with Fibrosis Progression after OLT
M. Sterneck¹, B. Sultani², M. Rodriguez Lago³, E. Grabhorn⁴, A. Briem-Richter⁴, U. Herden⁵, L. Fischer⁵
¹University Medical Center Hamburg Eppendorf, Hamburg, Germany, ²University Transplant Center, University Medical Center Hamburg Eppendorf, Hamburg, Germany, ³Depatment of Medicine, University Medical Center Hamburg Eppendorf, Hamburg, Germany, ⁴Department of Paediatric Medicine, University Medical Center Hamburg Eppendorf, Hamburg, Germany, ⁵Department of Visceral Transplantation, University Medical Center Hamburg Eppendorf, Hamburg, Germany
*Purpose: For decades, donor-specific antibodies (DSA) have been thought not to be clinically relevant in orthotopic liver transplantation (OLT). However, recent studies have shown a…
2019 American Transplant Congress
Chronic Changes on Time Zero Living Donor Allograft Biopsy Do Not Portend Future Kidney Function
A. Agarwal¹, A. Sites², K. L. Brayman¹, A. Doyle³, J. Oberholzer¹, A. Nishio-Lucar³
¹Surgery, University of Virginia, Charlottesville, VA, ²Transplant, University of Virginia, Charlottesville, VA, ³Medicine, University of Virginia, Charlottesville, VA
*Purpose: The predictive ability of implantation biopsies of kidney allografts on either future recipient or living donor kidney function has not been fully elucidated. Herein,…