ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Long Term Follow-Up of the Use of Checkpoint Inhibitors in Kidney Transplant Recipients

    K. Venkatachalam, R. Delos Santos, T. Alhamad

    Transplant nephrology, Washington University, St. Louis, MO

    *Purpose: To report the long term impact of check point inhibitors in patient and allograft survival among kidney transplant recipients.*Methods: We report follow up of…
  • 2019 American Transplant Congress

    EBV+ PTLD in the Modern Immunosuppression Era: Role of EBV Serology and DNAemia-Preliminary Data from CTOT-C06

    O. M. Martinez1, S. M. Krams1, M. A. Robien2, M. Lapasaran1, S. D. Boyd1, B. Armstrong3, C. Twist4, K. Weinberg1, D. Gratzinger1, B. Tan1, M. Sever3, D. Ikle3, M. Brown2, D. Bernstein1, C. O. Esquivel1

    1Stanford University Sch of Med, Stanford, CA, 2NIAID/NIH, Rockville, MD, 3Rho, Chapel Hill, NC, 4Roswell Park, Buffalo, NY

    *Purpose: Post-transplant lymphoproliferative disorder (PTLD) remains a serious problem in the pediatric transplant population. The Clinical Trials of Organ Transplantation in Children (CTOT-C)-06 is an…
  • 2019 American Transplant Congress

    Utilization of Hepatitis C Donors is Safe and Cost Effective

    J. Shaw, D. Reino, N. Kapila, K. Al Khalloufi, S. Ebaid, S. Rhazouani, X. Zervos, J. Vanatta, N. Agrawal

    Cleveland Clinic, Weston, FL

    *Purpose: The use of hepatitis C (hep C) positive donors has become increasingly attractive with the advent of improved curative pharmacologic treatments. As a result…
  • 2019 American Transplant Congress

    The Therapeutic Potential of Ex Vivo Induced Monocytic Myeloid-Derived Suppressor Cells from Bone Marrow in a Mouse Cardiac Allotransplantation Model

    K. Uchida, K. Fujimoto, E. Yin, H. Bashuda, K. Okumura, K. Takeda

    Juntendo University Atopy Research Center, Tokyo, Japan

    *Purpose: Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population that have the ability to cause immunosuppression. In recent years, MDSCs have attracted attention as a…
  • 2019 American Transplant Congress

    Organ Transportation by Drone: Surgeon Perspectives

    T. Talaie1, R. Barth2, J. R. Scalea1

    1University of Maryland, Baltimore, MD, 2Surgery, University of Maryland, Baltimore, MD

    *Purpose: We recently reported on the first transport of a human kidney using a drone. Ahead of large scale adoption of such a technology, understanding…
  • 2019 American Transplant Congress

    Kidney Allografts Induce Systemic Tolerance of Heart Allografts and is Dependent on Foxp3+ Cells

    C. Yang1, J. Ge1, P. S. Russell1, J. C. Madsen1, A. Alessandrini1, R. B. Colvin2

    1Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, 2Department of Pathology, Massachusetts General Hospital, Boston, MA

    *Purpose: We have successfully achieved cardiac allograft tolerance in both pigs and NHP by donor kidney co-transplantation. The mechanism of Kidney Induced Cardiac Allograft Tolerance…
  • 2019 American Transplant Congress

    Superiority of Donor-Specifically vs. Polyclonally Expanded Regulatory T Cells in Controlling Graft Rejection in the NSG Mouse Human Skin Graft Model

    J. H. Voss1, F. Zheng1, M. D. Jendrisak2, J. R. Leventhal1, Z. J. Zhang1, J. M. Mathew1

    1Surgery – Comprehensive Transplant Center, Northwestern University, Chicago, IL, 2Gift of Hope Organ & Tissue Donor Network, Itasca, IL

    *Purpose: Naturally occurring CD4+CD25highFOXP3+ Regulatory T cells (Tregs) function as mediators of immune homeostasis. So, they are beginning to be utilized for controlling hyper-immunity and…
  • 2019 American Transplant Congress

    Investigation and Regulation of Induced Anti-Pig Antibody Production in GTKO Pig-to-Cynomolgus Monkey Artery Retransplantation

    S. Hurh1, E. Lee1, J. Jeong2, G. Lee1, S. Park1, S. Ahn3, S. Min3, C. Ahn4

    1Biomedical Research Institute, Seoul National University Hospital, Seoul, Korea, Republic of, 2Department of Nephrology, Ajou University School of Medicine, Suwon, Korea, Republic of, 3Department of Surgery, Seoul National University Hospital, Seoul, Korea, Republic of, 4Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea, Republic of

    *Purpose: Although the recent progress in xenograft survival in pig-to-nonhuman primate heart and kidney transplantation, little is known about retransplantation in pig antigen-sensitized recipient. This…
  • 2019 American Transplant Congress

    Room for Optimism; Improvement in Long-Term Patient and Graft Survival of Kidney Transplants in the United States over the past Three Decades

    C. Wu, A. Rana, N. Galvan, C. O'Mahony, J. Goss, B. Murthy

    Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX

    *Purpose: Previous studies indicated that the short-term (1 year) allograft survival of kidney transplants has improved significantly over the years. However, less is known about…
  • 2019 American Transplant Congress

    Significant Increase in Moderate to High KDPI Kidney Transplants Using a Multi-Operational Approach: Results from the COIIN (Collaborative Innovation and Improvement Network) Initiative

    T. Pesavento1, J. Foutz2, K. Sisaithong2, D. Klassen2, L. Stillion1, A. Rajab1, R. Pelletier3, K. Washburn1, H. Tosoc-Haskell2

    1Ohio State University, Columbus, OH, 2UNOS, Richmond, VA, 3Robert Wood Johnson, New Brunswick, NJ

    *Purpose: Kidney transplant (KTx) utilization of moderate to high KDPI (MH-KDPI) deceased donor kidneys remains an opportunity to reduce organ discards. We participated in COIIN,…
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