ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Transplantation of the Highly Sensitized Renal Transplant Candidate in the Post-KAS Era: Who is Left Out?

    C. Schinstock, B. Smith, A. Bentall, M. Stegall

    Mayo Clinic, Rochester, MN

    *Purpose: Highly sensitized kidney transplant candidates are given high priority under the new kidney allocation system (KAS), but it is unclear if all sensitized candidates…
  • 2019 American Transplant Congress

    Conversion from Tacrolimus Immediate Release to Tacrolimus Extended Release (Envarsus XR®): A Real World Cohort Highlighting Dosing Variability among Patients

    K. D. Belfield1, D. Malhotra2, M. Waleed3, E. A. Cohen1

    1Department of Pharmacy, Yale New Haven Hospital, New Haven, CT, 2Yale University School of Medicine, New Haven, CT, 3University of Connecticut School of Pharmacy, Storrs, CT

    *Purpose: Tacrolimus extended release (TacER) (Envarsus XR®) has become an attractive alternative to tacrolimus immediate release (TacIR) due to its once daily dosing scheme, favorable…
  • 2019 American Transplant Congress

    Delayed Achievement of Therapeutic Tacrolimus Levels with De Novo Extended-Release Tacrolimus Tablets and the Incidence of Rejection in Kidney Transplant Patients

    C. E. Carthon1, J. C. Hagopian1, S. E. January1, A. Gharabagi1, R. Delos Santos2, T. A. Horwedel3

    1Pharmacy, Barnes-Jewish Hospital, Saint Louis, MO, 2Nephrology, Washington University School of Medicine, Saint Louis, MO, 3Veloxis Pharmaceuticals, Inc., Cary, NC

    *Purpose: Early therapeutic tacrolimus levels have been associated with improved outcomes in renal transplant recipients while lower exposure to tacrolimus during the first week of…
  • 2019 American Transplant Congress

    Early Rejection Outcomes with IL-2 vs. ATG Induction among Kidney Transplant Recipients Induction Differences with Early Steroid Withdrawal

    C. Burelli, A. Szczepanik, K. Yadav, E. Sanchez, M. Debroy, V. Humphreville, J. Rabets, A. Padiyar, N. Sarabu, A. Jittirat, A. Palanisamy, K. Chavin

    University Hospitals Cleveland Medical Center, Cleveland, OH

    *Purpose: Early steroid withdrawal in kidney transplant (Ktx) patients is controversial and has demonstrated an increased risk of acute rejection with similar long-term outcomes. Data…
  • 2019 American Transplant Congress

    Pre-Liver Transplant Renal Dysfunction is an Independent Predictor of Post-Liver Transplant Return to the Operating Room

    H. M. Wadei, M. L. Mai, C. Taner, A. P. Keaveny, S. Mao, P. Abader, P. Kroner, K. Croome

    Department of Transplant, Mayo Clinic, Jacksonville, FL

    *Purpose: Pre-liver transplant (LT) renal dysfunction predicts worse outcomes post-LT but the reasons for this are unclear. We aimed at identifying the effect of pre-LT…
  • 2019 American Transplant Congress

    Higher Population Donor Service Areas Are Associated With Lower Meld At Death On Wait List And Higher Meld At Removal For “Too Sick

    Y. Hung, Y. Bababekov, C. Rickert, Y. Hsu, D. Chang, H. Yeh

    Massachusetts General Hospital, Boston, MA

    *Purpose: Plans for distance based allocation in liver transplantation have raised concerns that patients listed in more rural Donor Service Areas (DSAs) will be disadvantaged…
  • 2019 American Transplant Congress

    Comparison of Two Dosing Regimens of Valganciclovir for Cytomegalovirus Prophylaxis in High-Risk Liver Transplant Recipients

    A. L. Bixby, L. Fitzgerald, L. Cotiguala, J. M. Park, D. Kaul, C. Sonnenday, S. Tischer

    Michigan Medicine, Ann Arbor, MI

    *Purpose: Significant controversy surrounds the optimal dose and duration of valganciclovir (VGCV) to prevent CMV in high-risk (D+/R-) liver transplant (LT) recipients. High doses cause…
  • 2019 American Transplant Congress

    Is Exposure to Wildfires Associated with Invasive Fungal Infections?

    J. S. Mulliken1, A. G. Rappold2, M. Fung1, J. M. Babik1, S. B. Doernberg1

    1Division of Infectious Diseases, University of California San Francisco, San Francisco, CA, 2National Health and Environmental Effects Research Laboratory, United States Environmental Protection Agency, Durham, NC

    *Purpose: In recent decades, climate change and other factors have led to a global increase in wildfires. After a large fire in Northern California in…
  • 2019 American Transplant Congress

    Efficacy of Filgrastim in Solid Organ Transplant Recipients

    M. Spinner1, K. Gaffney1, S. Gundling2

    1Pharmacy, Cleveland Clinic, Cleveland, OH, 2University of Pittsburgh School of Pharmacy, Pittsburgh, PA

    *Purpose: Neutropenia frequently occurs after solid organ transplantation (SOT) due to immunosuppression, antiviral prophylaxis, or viral infections. Immunosuppression reduction or antiviral prophylaxis minimization can lead…
  • 2019 American Transplant Congress

    Treprostinil Attenuates Renal Ischemia-Reperfusion Injury in Rat

    M. Ding1, E. Tolbert2, M. Birkenbach3, C. Chung4, R. Gohh5, F. Akhlaghi1, N. Ghonem1

    1Biomedical and Pharmaceutical Sciences, URI, Kingston, RI, 2Nephrology, Rhode Island Hsopital, Providence, RI, 3Pathology, Rhode Island Hospital, Providence, RI, 4Surgery, Rhode Island Hospital, Providence, RI, 5Organ Transplantation, Rhode Island Hospital, Brown University, KINGSTON, RI

    *Purpose: Kidney transplantation (KTx) is the optimal treatment for end-stage renal diseases. The surgical procedure of KTx inherently requires cold ischemic preservation and warm reperfusion…
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