Am J Transplant, Volume 19, Suppl 3 Archives - Page 78 of 214 - ATC Abstracts

2019 American Transplant Congress
Azole Use and Fungal Pathogens in Cystic Fibrosis versus Non-Cystic Fibrosis Lung Transplant Recipients
F. J. Marco Canosa¹, K. Brizendine², H. Hassouna³
¹Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH, ²Infectious Disease, Cleveland Clinic Foundation, Cleveland, OH, ³Infectious Disease, Spectrum Health Infectious Disease, Grand Rapids, MI
*Purpose: Cystic fibrosis (CF) patients exhibit unique pharmacokinetic principles. Azole antifungals show marked inter- and intra-patient variability. We aimed to improve itraconazole (ITR) use and…
2019 American Transplant Congress
Multi-Disciplinary Considerations Concerning the Impacts of Kidney Transplantation on Cervical and Lumbar Spinal Fusion Operations
L. Mugge, C. Gallagher, W. Qu, A. Caras, N. Henkel, O. Ekwenna, J. Ortiz
The University of Toledo Medical Center, Toledo, OH
*Purpose: Improvements in postoperative care for renal transplant patients has increased both the duration and quality of life for patients. These patients are now able…
2019 American Transplant Congress
Incisional Hernia Repair Post Liver and or Kidney Transplantation
J. Buggs¹, A. Brando², J. Sokolich¹, E. Rogers¹, A. Kumar³, V. Bowers¹
¹Tampa General Hospital, Tampa, FL, ²University of Tampa, Tampa, FL, ³University of South Florida, Tampa, FL
*Purpose: The literature has demonstrated worse patient survival rates with incisional hernias in abdominal transplant patients. The purpose of this study was to evaluate patient…
2019 American Transplant Congress
Poor Nutritional And Bone-mineral Density Parameters Pretransplant Predict Complications Posttransplant
A. Padiyar¹, A. Agrawal¹, D. Hricik¹, J. Kerner², J. Benavides², N. Sarabu¹, A. Jittirat¹, K. Yadav², E. Sanchez², M. DeBroy², V. Humphreville², J. Rabets², A. Palanisamy², K. Chavin²
¹Medicine, Nephrology, University Hospitals Cleveland Medical Center, Cleveland, OH, ²Transplant Surgery, University Hospitals Cleveland Medical Center, Cleveland, OH
*Purpose: Poor nutritional parameters in patients with ESRD on hemodialysis are associated with increased rates of hospitalization. The impact of malnutrition and inflammation and poor…
2019 American Transplant Congress
Liver Waitlist Dropout and Transplant Rates for Metropolitan vs. Non-Metropolitan Candidates
D. Schladt¹, T. Weaver¹, J. Pyke¹, A. Herreid¹, B. Thompson¹, B. Kasiske¹, J. Snyder¹, W. Kim², J. Lake³, A. Israni¹
¹SRTR, Minneapolis, MN, ²Stanford Univ, Stanford, CA, ³Univ of Minnesota, Minneapolis, MN
*Purpose: Rural candidates may be disadvantaged on the liver waiting list. We evaluated rates and hazards of waitlist dropout and transplant by urbanicity.*Methods: We selected…
2019 American Transplant Congress
Cluster Analysis of Microvascular Inflammation in Indication Biopsies Unveils Distinct Pathological and Immunological Phenotypes with Prognostic Implications
J. Malheiro¹, A. Silva¹, S. Santos¹, S. Tafulo², L. Martins¹, L. Dias¹, A. Castro-Henriques¹
¹Centro Hospitalar do Porto, Porto, Portugal, ²IPST_Porto, Porto, Portugal
*Purpose: We aimed to define distinct pathological and immunological clusters of 80 cases of MVI diagnosed in indication biopsies and evaluate their prognostic implications.*Methods: The…
2019 American Transplant Congress
Peri-Operative Basiliximab is Not Associated with Post-Transplant Hepatocellular Carcinoma Recurrence in Liver Transplant Recipients
D. Salerno¹, N. Lange¹, E. Simoneau², C. Sammons³, D. Bley¹, R. S. Brown Jr⁴, J. Emond², K. Halazun⁵
¹Pharmacy, NewYork-Presbyterian Hospital, New York, NY, ²Surgery, Columbia University Irving Medical Center, New York, NY, ³Pharmacy, Hospital of the University of Pennsylvania, Philadelphia, PA, ⁴Medicine, Weill Cornell Medicine, New York, NY, ⁵Surgery, Weill Cornell Medicine, New York, NY
*Purpose: The optimal immunosuppression for liver transplant recipients (LTR) with hepatocellular carcinoma (HCC) is unknown. Basiliximab, an interleukin-2 receptor antagonist (IL-2RA), confers immunosuppression for LTR…
2019 American Transplant Congress
Fatal Graft versus Host Disease in Liver Transplantation. An Analysis of UNOS Registry
S. Nagai¹, A. Yoshida¹, R. Salgia², M. Abouljoud¹, D. Moonka²
¹Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI, ²Gastroenterology, Henry Ford Hospital, Detroit, MI
*Purpose: Graft-versus-host disease (GVHD) after liver transplant is a rare complication. This study aimed to analyze the UNOS registry to identify risk factors for fatal…
2019 American Transplant Congress
A Mouse Model of Vascularized Heterotopic Spleen Transplantation for Studying Lymphocyte Biology and Transplant Immunity
L. Qiu¹, J. Wang², R. Fernandez³, X. Yeap¹, S. Han¹, F. Zheng¹, C. Lin², Z. J. Zhang¹
¹Comprehensive Transplant Center, Department of Surgery, Northwestern University, Chicago, IL, ²Northwestern University, Chicago, IL, ³Department of Surgery, Northwestern University, Chicago, IL
*Purpose: Spleen-derived lymphocytes and myeloid cell populations are critical to the development of organ transplant ischemia-reperfusion injury (IRI) and allograft rejection. In this study, we…
2019 American Transplant Congress
The Adapter Protein TSAd Regulates Mitochondrial Lck Activity and is Potent to Enhance Immunoregulation Following Transplantation
J. Wedel¹, M. P. Stack¹, T. Seto¹, K. Liu¹, I. E. Stillman², D. M. Briscoe¹
¹Transplant Research Program, Boston Children's Hospital, Harvard Medical School, Boston, MA, ²Department of Pathology, Beth Israel Deaconess Center, Harvard Medical School, Boston, MA
*Purpose: T cell Specific Adaptor Protein (TSAd, encoded by the SH2D2A gene) is an intracellular adapter molecule that binds Lck and functions to elicit T…