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American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Long-term Impact of Antihypertensive Treatment and Tacrolimus Dose in Renal Allograft Recipients 5 Years Post-Transplantation

    D. Rush1, S. Cockfield2, S. Wilson3, J. Schwartz4

    1University of Manitoba, Winnipeg, MB, Canada, 2University of Alberta Hopspital, Edmonton, AB, Canada, 3Astellas Pharma Global Development, Northbrook, IL, 4Astellas Pharma US, Northbrook, IL

    *Purpose: Inflammation and fibrosis after renal transplantation may be modulated by optimizing tacrolimus exposure, or by use of angiotensin-converting enzyme inhibitors (ACEi), or angiotensin receptor…
  • 2019 American Transplant Congress

    The Utility of Donor and Recipient BK Virus Antibody Testing Prior to Renal Transplantation in Risk Assessment for Developing BK Viremia

    N. Donmez, S. I. Al-Akash

    Driscoll Children's Hospital, Corpus Christi, TX

    *Purpose: The correlation between donor (DON) and recipient (REC) BKV antibody (AB) titers and BK viremia in renal transplant (RTx) has not been well-studied in…
  • 2019 American Transplant Congress

    Cytokine Profiles in Children after Pediatric Kidney Transplantation with Acute Cellular Compared to Chronic Active Antibody-Mediated Rejection

    N. Borsum, T. Ahlenstiel-Grunow, L. Pape

    Pediatric Nephrology, Hannover Medical School, Hannover, Germany

    *Purpose: Until now, no blood biomarkers have been identified to enable early diagnosis of acute cellular or chronic active antibody-mediated rejection (cABMR) after pediatric kidney…
  • 2019 American Transplant Congress

    Tandem Mass Tags Based Liquid Chromatography/ Mass Spectrometry Analysis of Quantitative Proteomic Changes in Renal Allograft Biopsies with Polyomavirus BK Nephropathy

    F. Fang, P. Liu, L. Song, Y. Zhao, G. Zeng, G. Tseng, K. Xiao, P. Randhawa

    University of Pittsburgh, Pittsburgh, PA

    *Purpose: Transcriptomics analyses have not generated reliable means to distinguish T-cell mediated rejection (TCMR) from BK virus nephropathy (BKVN). Proteomics-based approaches deserve further exploration since…
  • 2019 American Transplant Congress

    Donor Hepatitis C Seropositivity Confers Poorer Post-transplant Outcomes In Recipients Of Marginal Livers In The Post-hepatitis C Treatment Era

    M. B. Shah, M. Gupta, X. Mei, R. Gedaly

    University of Kentucky, Lexington, KY

    *Purpose: Since the introduction of newer antiretroviral therapies, utilization of hepatitis C (HCV) positive livers has increased significantly for HCV recipients. In an effort to…
  • 2019 American Transplant Congress

    Increasing the Number of Liver Transplants through Active Review of Offers Turned Down

    M. L. Melcher, C. A. Bonham, A. Gallo, W. Concepcion, I. Jacobson, C. O. Esquivel

    Stanford University, Palo Alto, CA

    *Purpose: To increase the number of patients benefiting from a liver transplant, a university transplant program instituted a weekly review meeting of the transplant surgeons…
  • 2019 American Transplant Congress

    Pediatric Liver Transplantation during the Opioid Epidemic: UNOS Analysis of Organ Availability and Outcomes

    J. Chu1, J. Franke2, C. Almy1, R. Annunziato2, R. Arnon1

    1Recanati/Miller Transplant Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 2Psychology, Fordham University, New York, NY

    *Purpose: The opioid epidemic has been largely responsible for the 3-fold increase in deaths due to drug overdose over the last 15 years. Whether this…
  • 2019 American Transplant Congress

    Correlation between Gene Expression and Histology in Transbronchial Lung Transplant Biopsies

    B. Adam, K. Du, S. Rotich, M. Mengel

    University of Alberta, Edmonton, AB, Canada

    *Purpose: Transbronchial lung transplant biopsies (TBBx) are limited by non-specific histologic lesions and suboptimal interobserver reproducibility. Gene expression offers a potentially more precise, objective and…
  • 2019 American Transplant Congress

    Azole Use and Fungal Pathogens in Cystic Fibrosis versus Non-Cystic Fibrosis Lung Transplant Recipients

    F. J. Marco Canosa1, K. Brizendine2, H. Hassouna3

    1Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH, 2Infectious Disease, Cleveland Clinic Foundation, Cleveland, OH, 3Infectious Disease, Spectrum Health Infectious Disease, Grand Rapids, MI

    *Purpose: Cystic fibrosis (CF) patients exhibit unique pharmacokinetic principles. Azole antifungals show marked inter- and intra-patient variability. We aimed to improve itraconazole (ITR) use and…
  • 2019 American Transplant Congress

    Multi-Disciplinary Considerations Concerning the Impacts of Kidney Transplantation on Cervical and Lumbar Spinal Fusion Operations

    L. Mugge, C. Gallagher, W. Qu, A. Caras, N. Henkel, O. Ekwenna, J. Ortiz

    The University of Toledo Medical Center, Toledo, OH

    *Purpose: Improvements in postoperative care for renal transplant patients has increased both the duration and quality of life for patients. These patients are now able…
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