ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Cholecystitis in High-Acuity Patients Undergoing Liver Transplantation: A Five-Year Analysis of Incidence, Causes and Impact

    D. S. Graham, T. Ito, M. M. Lu, J. DiNorcia, V. G. Agopian, H. Yersiz, D. G. Farmer, R. W. Busuttil, F. M. Kaldas

    Dumont-UCLA Liver Transplant Center, Department of Surgery, UCLA School of Medicine, Los Angeles, CA

    *Purpose: While the incidence of gallbladder pathology is well described in the general population, there is almost no data on cholecystitis in liver transplant candidates…
  • 2019 American Transplant Congress

    Hypothermic Machine Perfusion Protects Donation After Cardiac Deathliver Graft Through Gstm1-mediated Cytochrome P450 Exogenous Substance Metabolism Pathway

    W. Liang, S. Ye, Z. Zhong, Q. Hu, Y. Wang, Q. Ye

    Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases, Wuhan, China

    *Purpose: Donation after cardiac death (DCD) is the mainly resource to relieve organ-transplantation shortage. Our previous research have confirmed that the function of DCD liver…
  • 2019 American Transplant Congress

    Transfer of Healthy Mitochondria in Established Ischemic Injury Reduces Progression to Interstitial Fibrosis and Tubular Atrophy

    A. Bajwa1, V. Bontha1, D. Maluf1, J. Eason2, V. Mas3

    1UTHSC, Memphis, TN, 2Director of Transplant Institute, Memphis, TN, 3Director of Transplant Research Institute, Memphis, TN

    *Purpose: Ischemia induces altered bioenergetics with increased mitochondrial swelling and reactive oxygen species (ROS) and ultimately degradation of cellular function. Therapeutic interventions that target to…
  • 2019 American Transplant Congress

    Characterization of Circulating T-cell Specific Exosomes during Acute Rejection in Murine Heart Transplantation Model

    R. Hu1, V. Korutla1, L. Korutla1, S. Rostami1, A. Habertheuer1, S. Addya2, J. Harmon1, P. Zielinski1, S. Reddy1, A. Freas1, C. Ram1, A. Naji1, P. Vallabhajosyula1

    1Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, 2Thomas Jefferson University, Philadelphia, PA

    *Purpose: Exosomes are nanoparticles (30-200nm) released by many cell types. They carry nucleic acid and proteins that may reflect conditional changes in their tissue counterparts.…
  • 2019 American Transplant Congress

    Use of TruGraf Serial Testing for Confirming Stability in Kidney Transplant Patients with Stable Renal Function

    V. Peddi1, C. Schieve2, S. Rose2, M. First2

    1California Pacific Med Ctr, San Francisco, CA, 2Transplant Genomics Inc, Mansfield, MA

    *Purpose: The objectives of this study were to model serial TruGraf testing in stable kidney transplant recipients and to demonstrate the potential clinical utility of…
  • 2019 American Transplant Congress

    Need of a New Formula to Estimate Creatinine Clearance in Immediate Post Kidney Transplant Period with Functioning Allograft

    A. B. Jain1, U. Farooq2, A. Brooks1, T. Dohi1, F. Butt1, Z. Kadry1

    1Surgery ( Transplant), Penn State Milton Hershey Medical Center, Hershey 17033, PA, 2Medicine( Neprhology), Penn State Milton Hershey Medical Center, Hershey, PA

    *Purpose: Introduction: Post kidney transplant (KTx), with functioning renal allograft, serum creatinine continues to decrease at a variable rate until it stabilizes after a few…
  • 2019 American Transplant Congress

    Could Intravenous Iron Strengthen The Chances Of Heart Transplantation For Patients With Left Ventricular Assist Devices?

    A. Mardis1, C. Mardis2, J. Barham3, A. Poole3, S. Branham3, R. Napier4, J. Martin3, P. McCann4

    1Department of Pharmacy, Palmetto Health, Columbia, SC, 2Clinical Pharmacy and Outcomes Sciences, University of South Carolina, Columbia, SC, 3Cardiothoracic Surgery, Palmetto Health, Columbia, SC, 4Cardiology, Palmetto Health, Columbia, SC

    *Purpose: Iron deficiency anemia (IDA) is prevalent in patients supported by left ventricular assist devices (LVADs), is associated with functional limitations, and often warrants blood…
  • 2019 American Transplant Congress

    Immune Privilege May Predispose Patients after Orthotopic Heart Transplantation to Develop Recipient to Donor Atrial Connections Associated with Atrial Arrhythmias

    B. Herweg1, M. Nellaiyappan1, T. Tran1, G. Mabry1, K. Weston1, H. J. Eisen2, M. Weston3

    1Cardiovascular Sciences, University of South Florida Morsani College of Medicine, Tampa, FL, 2Heart and Vascular Institute, Pennsylvania State University, Hershey, PA, 3Tampa General Hospital, Tampa, FL

    *Purpose: The formation of functional electrical inter-atrial connections (IAC) between recipient and donor atria after orthotopic heart transplantation (OHT) is intriguing and its mechanism is…
  • 2019 American Transplant Congress

    Rabbit Anti-Thymocyte Globulin (rATG) Induction in Heart Transplant Recipients at High Risk for Rejection

    B. Kitto1, B. Baetz1, S. Krim2, H. Patel2, S. Mandras2, S. Desai2, C. Eiswirth2, H. Ventura2, S. Thai1

    1Pharmacy, Ochsner Medical Center, New Orleans, LA, 2Heart Transplant, Ochsner Medical Center, New Orleans, LA

    *Purpose: To assess the safety and efficacy of rATG induction in heart transplant recipients at high risk for rejection.*Methods: This was a single-center, retrospective study…
  • 2019 American Transplant Congress

    Implementation of Novel Machine-Learning Techniques to Tailor Donornet® Organ Offers to Center and Surgeon Preference

    A. C. Perez-Ortiz, N. Elias

    Transplant Center, Massachusetts General Hospital, Boston, MA

    *Purpose: Real-time communication regarding organ placement is critical. For this purpose, UNOS launched DonorNet®, a computerized allocation algorithm, to aid and facilitate organ placement. However,…
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