2019 American Transplant Congress
Physiochemical Hla Properties Identify Low Immunogenic Donor/recipient Pairs Predicting Long-term Kidney Graft Survivals
1Gift of Life Michigan, Ann Arbor, MI, 2University of Toledo, Toledo, OH
*Purpose: Although it is well-recognized that HLA matching improves the long-term kidney graft survival, less than 10% of transplants are currently HLA matched. We measured…2019 American Transplant Congress
The Risk of Systematic Error in Liver Transplant Opioid Research
Medical University of South Carolina, Charleston, SC
*Purpose: Opioid use before and after liver transplant is strongly associated with morbidity and mortality; yet data assessing opioid utilization has centered on sources with…2019 American Transplant Congress
Circulating Donor Specific Antibody and Biopsy C4d Positivity in Pancreas Rejection Increase the Probability of Earlier Return to Insulin after Rejection
*Purpose: Outcome data following rejection in pancreas recipients are sparse. We sought to study the influence of C4d positivity and the presence of circulating DSA…2019 American Transplant Congress
Measuring and Monitoring Disparities in Access to Kidney Transplantation Associated with Being Listed for a Multi-Organ Transplant (MOT)
*Purpose: In 2018, the OPTN published a new methodology for measuring and monitoring disparities in access to deceased donor kidney (KI) transplantation (Tx) among kidney-alone…2019 American Transplant Congress
The Impact of Sleeve Gastrectomy Following Liver Transplant in Patients with Non-Alcoholic Steatosis: A Five-Year Experience
*Purpose: Non-alcoholic steatohepatitis (NASH) cirrhosis is an increasingly common indication for liver transplantation (LT) in the United States and obese patients continue to be at…2019 American Transplant Congress
The Effect of Kidney Transplantation on Neurocognitive Function: A Prospective Study
Vanderbilt University Medical Center, Nashville, TN
*Purpose: The effect of kidney transplantation on global cognition and executive function in patients with advanced kidney disease is unknown.*Methods: We prospectively enrolled patients scheduled…2019 American Transplant Congress
Granulocyte – Colony Stimulating Factor (G-CSF) and Granulocyte – Macrophage Colony Stimulating Factor (GM-CSF) Administration Augments the Incidence of Peripheral Blood Suppressive Regulatory T Cells in Nonhuman Primates
*Purpose: Granulocyte-colony stimulating factor (G-CSF) and granulocyte-macrophage CSF (GM-CSF) are known to mobilize immune cells to the peripheral blood. We evaluated regulatory T cells (Treg)…2019 American Transplant Congress
Glycogen Synthase Kinase 3alpha Serine 21 Phosphorylation Inhibits Hepatocyte Autophagy to Facilitate Liver Ischemia Reperfusion Injury
*Purpose: Glycogen synthase kinase 3 (Gsk3) has α and β isoforms. They are constitutively active in cells and inhibited upon stimulations by N-terminal serine phosphorylation.…2019 American Transplant Congress
TDCA/Valine Reverse Obesity and Ameliorate Alloimmune Responses through a Decreased Hypothalamic Expression of MCH
1Brigham and Women's Hospital, Boston, AL, 2Beth Israel Deaconess Medical Center, Boston, AL
*Purpose: Obesity is associated with low grade inflammation and bariatric surgery is the only effective treatment in reducing excess weight both pre- and post-transplant.*Methods: Here,…2019 American Transplant Congress
The Evolving Clinical Presentation of Acute Rejection in Face Transplantation
Plastic and Reconstructive Surgery, Brigham and Women's Hospital, Boston, MA
*Purpose: Clinical signs such as erythema or edema are traditionally helpful to diagnose Acute rejection (AR) in face transplantation (FT) in the early follow-up. The…
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