Am J Transplant, Volume 19, Suppl 3 Archives - Page 70 of 214 - ATC Abstracts

2019 American Transplant Congress
Galectin-3 and Long-Term Graft Failure in Renal Transplant Recipients: A Prospective Cohort Study
C. G. Sotomayor¹, C. A. Keyzer¹, J. L. Anderson¹, R. O. Gans², I. M. Nolte³, M. H. de Borst¹, S. P. Berger¹, G. J. Navis¹, R. A. de Boer⁴, S. J. Bakker¹
¹Division of Nephrology, Department of Internal Medicine, University Medical Center Groningen, Groningen, Netherlands, ²Department of Internal Medicine, University Medical Center Groningen, Groningen, Netherlands, ³Department of Epidemiology, University Medical Center Groningen, Groningen, Netherlands, ⁴Department of Cardiology, University Medical Center Groningen, Groningen, Netherlands
*Purpose: Galectin-3 has been associated with renal fibrosis and decline of renal function. We aimed to determine the association of galectin-3 with long-term risk of…
2019 American Transplant Congress
IL-6R Blockade with Tocilizumab Increases Tregs and Decreases Early Graft Inflammation in Kidney Transplant Recipients: Results of a Randomized Controlled Trial
S. Chandran, J. Leung, Z. Laszik, Q. Tang, C. Hu, M. Joanes, F. Vincenti
UCSF, San Francisco, CA
*Purpose: IL-6, a proinflammatory cytokine and key regulator of Treg/Th17 balance, is strongly associated with renal graft rejection. We hypothesized that IL-6 blockade with tocilizumab…
2019 American Transplant Congress
The Risk of Systematic Error in Kidney Transplant Opioid Research
J. N. Fleming, N. A. Pilch, S. Ball, P. K. Baliga, V. Rohan, D. J. Taber
Medical University of South Carolina, Charleston, SC
*Purpose: Opioid use before and after kidney transplant is strongly associated with morbidity and mortality; yet data assessing opioid utilization has centered on sources with…
2019 American Transplant Congress
Adult Living Donor vs. Deceased Donor Liver Transplant (LDLT vs. DDLT) at a Single US Center- Time to Change Our Paradigm for Liver Transplant
A. Humar, D. Jorgensen, S. Ganesh, A. Tevar, M. Molinari, C. Hughes
Thomas E Starzl Transplant Inst, Pittsburgh, PA
*Purpose: LDLT remains underutilized in the US. We compared outcomes between LDLT and DDLT at our center to highlight the advantages of LDLT.*Methods: Retrospective review…
2019 American Transplant Congress
Improving Access to Lung Transplant through Donor Strategy: A Decision Analysis
W. Tsuang, B. Udeh
Cleveland Clinic, Cleveland, OH
*Purpose: The use of Donation after Cardiac Death (DCD) donors in addition to Donation after Brain Death (DBD) donors may increase patient access to lung…
2019 American Transplant Congress
Platelets Augment Granzyme K Production By Macrophages In Antibody-mediated Rejection
J. Dhar, K. Keslar, R. Fan, N. Dvorina, W. Baldwin
Cleveland Clinic Main Campus, Lerner Research Institute, Cleveland, OH
*Purpose: When antibodies bind to MHC antigens on endothelial cells a cascade of responses is initiated including exocytosis of adhesion molecules followed by attachment and…
2019 American Transplant Congress
Variation in Racial Disparities in Liver Transplant Outcomes by Hospital Quality
K. Ross, R. Patzer, R. Lynch
Emory University, Emory Transplant Center, Atlanta, GA
*Purpose: Black patients experience inferior outcomes after liver transplant (LTx). Studies of other outcomes have shown that disparities are partially attributable to variation in quality…
2019 American Transplant Congress
Increasing Time-in-Therapeutic Range of Tacrolimus is Associated with Superior Outcomes in Living Kidney Transplants
T. Lin, T. Song, S. Yin, Y. Jiang, Z. Huang, X. Wang, J. Liu, Z. Wang
Organ Transplantation Center, Urology Department, Urology Research Institute, WestChina Hospital, Sichuan University, Chengdu, China
*Purpose: Tacrolimus-based regimens remain the backbone of maintenance immunosuppressive therapy in kidney transplant, and therapeutic drug monitoring of tacrolimus is necessary due to a narrow…
2019 American Transplant Congress
Positron Emission Tomography (PET-CT) Global Coronary Flow Reserve (CFR) Stratifies Cardiovascular Risk among Renal Transplant (RTx) Candidates
M. Minder, S. Mason, J. Ethington, R. McCubrey, D. Min, N. Sekaran, J. Orford, D. Morris, S. Anand, T. Srinivas
Intermountain Healthcare, Murray, UT
*Purpose: Chronic kidney disease (CKD) and diabetes (DM) are both associated with increased risk of coronary artery disease and Major Adverse Cardiovascular Events (MACE). The…
2019 American Transplant Congress
Chronic Kidney Disease among Liver Transplant Candidates: A Rising Burden and Its Impact on Post-Liver Transplant Outcomes
G. Cullaro¹, E. C. Verna², B. P. Lee¹, J. C. Lai¹
¹UCSF, San Francisco, CA, ²Columbia University, New York, NY
*Purpose: Chronic kidney disease (CKD) is the end manifestation of persistent renal damage, a pathology distinct from the reversible acute kidney injury (AKI). This distinction…