2019 American Transplant Congress
A Metagene Signature of Lymphocytic Bronchitis Following Lung Transplantation
*Purpose: Lymphocytic bronchitis (LB) precedes chronic lung allograft dysfunction (CLAD). Peri-vascular (A-grade) and peri-bronchiolar (B-grade) lymphocytic inflammation are traditional markers of acute cellular rejection. The…2019 American Transplant Congress
Implication of Melanocortin Receptors in Alloimmunity
Transplantation Research Center, Renal, Brigham and Women's Hospital, Boston, MA
*Purpose: Recent studies have indicated the importance of the melanocortin pathway in the regulation of immune responses. In particular, the role that melanocortin receptors (MCRs)…2019 American Transplant Congress
Not All Poor Metabolizers Are Clinically Equal: Evaluating Weight-Based Tacrolimus Outcomes in CYP3A Loss of Function Variants
Vidant Medical Center - Transplant Services, Greenville, NC
*Purpose: CYP3A polymorphisms are an important pharmacotherapeutic consideration due to the extensive CYP metabolism of tacrolimus (TAC) and variable expression among different races. The CPIC…2019 American Transplant Congress
Actions Speak Louder Than Labs – The Impact of Dialysis Compliance on Posttransplant Outcomes
*Purpose: Non-adherence is a modifable risk factor for poor posttransplant outcomes. While the factors contributing to posttransplant non-adherence are complex, noncompliance with the dialysis prescription…2019 American Transplant Congress
Response to Treatment in Kidney Recipients with Acute T Cell-Mediated Rejection: Major Impact of Inflammation in Sclerotic Cortical Parenchyma (i-IF/TA) and Donor-Specific Antibodies
Paris Translational Research Center for Organ Transplantation, Paris, France
*Purpose: The recent recognition of chronic TCMR phenotypes has fostered the need to better evaluate the response of acute TCMR to standard-of-care treatment.*Methods: Among 2905…2019 American Transplant Congress
Higher Level of Social Support is Associated with Higher Likelihood of Pursuit of Living Donor Kidney Transplant (LDKT)
*Purpose: LDKT is the optimal treatment for many patients with End Stage Kidney Disease (ESKD) , offering better clinical outcomes and quality of life. Studies…2019 American Transplant Congress
Primary Indications and Waitlist Status for Pediatric Living Donor Liver Transplants
*Purpose: Since 1989, living donor liver transplantation (LD) has been used for a selected population and has shown improved long-term graft survival. The aim was…2019 American Transplant Congress
Economic Impact of Donor Hepatitis C Kidney Transplantation: A Medicare Cost Analysis
*Purpose: In the era of highly effective direct-acting antiviral agents (DAAs), kidney transplant (KT) from Hepatitis C virus (HCV)-positive donors is increasingly considered as an…2019 American Transplant Congress
Plasmacytoid Dendritic Cell-Mediated Graft Prolongation Requires microRNA-181 and Semaphorin 4a
Stanford Univ School of Med, Stanford, CA
*Purpose: Dendritic cells (DCs) are antigen-presenting cells (APCs) important for initiating and coordinating the immune response. Plasmacytoid dendritic cells (pDCs) are a subset of DCs…2019 American Transplant Congress
Reduction In Early Readmission In Kidney Recipients – Outcomes At One Year With Standardized Intensive Follow Up
Glickman Urological and Kidney Institute CCF, Cleveland, OH
*Purpose: Kidney transplant recipients often experience frequent ED visits and high early hospital readmission (EHR) rates (within 30 days). We sought to decrease our preventable…
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