Am J Transplant, Volume 19, Suppl 3 Archives - Page 55 of 214 - ATC Abstracts

2019 American Transplant Congress
United Kingdom National Outcomes of Transplants from Paediatric Donors: 10 Years Experience
M. A. Khurram, N. Karydis, C. Callaghan, I. Loukopoulos, T. Kasimatis, P. Chandak, F. Calder, N. Mamode, N. Kessaris
Transplantation, Guy's and St Thomas NHS trust, London, United Kingdom
*Purpose: Paediatric donors have been contributing to the kidney donor pool but there are concerns regarding the small nephron mass, hyperfiltration, technical issues including risks…
2019 American Transplant Congress
Spindle and Kinetochore Associated Complex Subunit 3 Promotes Tumor Growth by Regulating CDK2/p53 Phosphorylation in Hepatocellular Carcinoma
Y. Hou¹, Z. Wang², L. Wu³
¹Organ Transplant Center, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China, ²The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China, ³Organ transplant center, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
*Purpose: Spindle and kinetochore-related complex subunit 3 (SKA3) is a part of the spindle and kinetochore-related complexes, which are crucial for the proper timing of…
2019 American Transplant Congress
Iguratimod Inhibits the Donor Specific Antibodies Production and Attenuates the Antibody Mediated Rejection in Rat Kidney Transplantation
Z. Wang, M. Zheng, H. Chen, S. Li, Z. Han, J. Tao, X. Ju, R. Tan, M. Gu
No.300 Guangzhou Road of Nanjing, Nanjing, China
*Purpose: Our study was designed to investigate the efficacy and related mechanisms of Iguratimod (T-614) in the inhibition of DSAs following kidney transplantation.*Methods: A rat…
2019 American Transplant Congress
Patient-Reported Transplant-Related Symptoms in Kidney Transplant Recipients
J. L. Beaumont¹, I. Purnajo¹, M. Polinsky², E. Alemao², M. J. Everly¹
¹Terasaki Research Institute, Los Angeles, CA, ²Bristol Myers Squibb, Princeton, NJ
*Purpose: Kidney transplant (txp) recipients experience many symptoms as a result of their transplant experience, immunosuppressive regimens, and comorbid conditions. The objective of this analysis…
2019 American Transplant Congress
Repeat-Pancreas Transplant after Pancreas Graft Failure in Simultaneous Pancreas and Kidney Transplants is Associated with Better Kidney Graft Survival
S. Parajuli, A. Arunachalam, K. Swanson, F. Aziz, N. Garg, R. Redfield, D. Kaufman, A. Djamali, J. Odorico, D. Mandelbrot
University of Wisconsin, Madison, WI
*Purpose: Simultaneous pancreas and kidney (SPK) transplant is usually the best option for the diabetic ESRD patient. But there is limited information about kidney graft…
2019 American Transplant Congress
Factors Related to International Travel for Transplantation among US-Listed Kidney Transplant Candidates
B. Koons¹, M. L. Henderson², A. G. Thomas³, T. Kear⁴, H. Moriarty⁴
¹School of Nursing, University of Pennsylvania, Philadelphia, PA, ²Department of Surgery in the Division of Transplantation, Johns Hopkins University, Baltimore, MD, ³Department of Epidemiology, University of North Carolina, Chapel Hill, NC, ⁴M. Louise Fitzpatrick College of Nursing, Villanova University, Villanova, PA
*Purpose: The aim of this study was to identify factors associated with international travel for transplantation among US-listed kidney transplant (KT) candidates.*Methods: Using 2010-2016 data…
2019 American Transplant Congress
The Comparative Safety and Efficacy of Direct Acting Oral Anticoagulants Relative to Warfarin Following Liver Transplantation
A. Santeusanio, A. Weinberg, T. Schiano
Mount Sinai Hospital, New York, NY
*Purpose: This study describes the comparative safety and efficacy of direct acting oral anticoagulants (DOACs) relative to warfarin following liver transplantation, at a large academic…
2019 American Transplant Congress
mTORC2 Restricts mTORC1 Metabolic Function in Dendritic Cells to Limit Their Allostimulatory Activity
H. Dai¹, A. Watson¹, A. Menk², D. Stolz³, G. Delgoffe², A. Thomson¹
¹Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA, ²Tumor Microenvironment Center, University of Pittsburgh Cancer Institute, Pittsburgh, PA, ³Department of Cell Biology, University of Pittsburgh, Pittsburgh, PA
*Purpose: Mechanistic target of rapamycin complex 2 (TORC2) deficiency in conventional dendritic cells (DC) results in their enhanced pro-inflammatory and T cell allostimulatory activity; however,…
2019 American Transplant Congress
Interruption of Notch Signaling via Blockade of Delta-Like Ligands 1 and 4 Prevents Co-Stimulation Blockade Resistant Allograft Rejection
A. Matar, Y. Dong, B. Lovasik, D. Mathews, A. Ghosh, C. Breeden, A. Stephenson, W. Kitchens, A. Adams
Surgery and Transplantation, Emory University, Atlanta, GA
*Purpose: Co-stimulation blockade (CoB) has emerged as a promising immunosuppression strategy with the advent of belatacept, a novel CTLA4-Ig fusion protein that blocks CD28-mediated T…
2019 American Transplant Congress
Apoptosis during Cold Ischemia and Rewarming Involves a Caspase Independent Pathway
S. Jain¹, R. Plenter², T. Nydam², A. Jani¹
¹Renal Division, University of Colorado, Aurora, CO, ²Transplant Microsurgery Program, University of Colorado, Aurora, CO
*Purpose: We have previously shown that hibernating ground squirrels (GS) tolerate core body temperatures of 4°C for several days with a heart rate that is…