ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    A Pilot Study of the mDOT Platform for Immunosuppression Adherence in Adult Kidney Transplant Recipients

    J. Langlee, L. Lees, A. Saha, D. Helfer, M. Waldram, A. Love, F. Rivera, A. Massie, D. Segev, D. Brennan, M. Henderson

    Johns Hopkins School of Medicine, Baltimore, MD

    *Purpose: The leading predictor of rejection, de novo DSA, graft loss, and death among adult kidney transplant (KT) recipients is immunosuppressive medication nonadherence. An estimated…
  • 2019 American Transplant Congress

    Incidence and Mortality of Renal Cell Carcinoma after Kidney Transplantation: A Meta-Analysis

    A. Chewcharat1, C. Thongprayoon2, B. Boonpheng3, A. Torres-Ortiz4, M. A Mao2, N. J Khoury5, W. Cheungpasitporn4

    1Harvard T.H. Chan, Boston, MA, 2Mayo Clinic, Rochester, MN, 3East Tennessee State University, Johnson City, TN, 4University of Mississippi Medical Center, Jackson, MS, 5Henry Ford Hospital, Detroit, MI

    *Purpose: The incidence and mortality of renal cell carcinoma (RCC) after kidney transplantation (KTx) remain unclear. This study's aims were 1) to investigate the pooled…
  • 2019 American Transplant Congress

    Paradoxical Liver Simulated Allocation Model (LSAM) Projections for Changes to Waitlist Mortality under Acuity Circle Distribution Model

    R. Lynch1, K. Ross1, S. Karp2

    1Emory, Atlanta, GA, 2Vanderbilt, Nashville, TN

    *Purpose: In December 2018, the United Network for Organ Sharing (UNOS) board voted to change liver transplant distribution from Donor Service Areas (DSAs) to a…
  • 2019 American Transplant Congress

    Mycophenolate Mofetil versus Azathioprine in Kidney Transplant Recipients on Steroid-Free Low-Dose Cyclosporine Immunosuppression: The ATHENA Trial

    P. Cravedi1, P. Ruggenenti2, E. Gotti2, A. Plati2, S. Sandrini3, N. Bossini3, F. Citterio4, E. Minetti5, D. Montanaro6, R. Tardanico3, E. Sabadini2, F. Gaspari7, A. Villa7, F. Peraro7, G. Remuzzi7

    1Mount Sinai, New York, NY, 2ASST Ospedale Papa Giovanni XXIII, Bergamo, Italy, 3ASST degli Spedali Civili, Brescia, Italy, 4Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy, 5ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy, 6Presidio Ospedaliero Universitario Santa Maria della Misericordia, Udine, Italy, 7Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy

    *Purpose: Registration trials using old sandimmune formulation of cyclosporine (CsA) led to the general idea that Mycophenolate Mofetil (MMF) prevents acute cellular rejection (ACR) more…
  • 2019 American Transplant Congress

    The Pregnancy Experiences of Uterus Transplant Recipients

    A. E. Wall, L. Johannesson, G. Testa, A. Warren

    Baylor University Medical Center, Dallas, TX

    *Purpose: The purpose of this study was to explore the pregnancy experiences of uterus transplant recipients through semi-structured interviews so as to develop a better…
  • 2019 American Transplant Congress

    Challenges to Inpatient Management Post Abdominal Wall Transplant (AWT) – From App’s Perspective

    K. Hattori, D. Sudan, K. Ravindra

    Duke University hospital, Durham, NC

    *Purpose: To highlight the unique features of caring for an AWT recipient and identify areas of improvement for future cases*Methods: AWT is an innovative adjunct…
  • 2019 American Transplant Congress

    MHC Cross-Dressing in Mixed Hematopoietic Chimerism

    B. Gonzalez Nolasco1, M. Wang1, W. Orent1, A. Prunevieille1, K. Pruner1, J. O1, J. Paster1, J. C. Madsen2, G. Benichou1

    1Department of Surgery, Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, 2Department of Surgery, Center for Transplantation Sciences, Division of Cardiac Surgery, Massachusetts General Hospital, Boston, MA

    *Purpose: Achieving specific long-term allograft survival without ongoing immunosuppression is one of the main objectives in transplantation. Mixed hematopoietic chimerism is a strategy that has…
  • 2019 American Transplant Congress

    Immunologically Tolerant Liver Transplant Recipients Are Characterized by Donor-Specific Hypo Responsiveness of Circulating T-cells

    A. A. Duizendstra1, R. J. Knegt de1, M. G. Betjes2, M. P. Peppelenbosch1, N. H. Litjens2, J. Kwekkeboom1

    1Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, Netherlands, 2Internal Medicine, Erasmus University Medical Center, Rotterdam, Netherlands

    *Purpose: Lifelong treatment with immunosuppressive drugs (IS) to prevent graft rejection in transplant recipients is accompanied by side effects. Some recipients are considered to be…
  • 2019 American Transplant Congress

    Targeted Epitope Mutagenesis as a Strategy to Decrease Xenoantibody Binding

    J. Ladowski, G. Martens, Z. Wang, L. Reyes, M. Tector, J. Tector

    University of Alabama-Birmingham, Birmingham, AL

    *Purpose: Xenotransplantation, the use of genetically-modified pig organs for transplantation, has been limited by antibody-mediated rejection. The generation of a three-antigen knockout pig provided a…
  • 2019 American Transplant Congress

    Impact of Glomerulitis at 4-Month Biopsy on Long Term Kidney Allograft Outcomes

    M. Whigham, G. Mour, M. Buras, S. Sukumaran Nair, A. Jaramillo, D. Ramon, R. Heilman

    Mayo Clinic, Phoenix, AZ

    *Purpose: Antibody mediated rejection (AMR) is diagnosed based on combination of elevated creatinine, histopathological findings defined as glomerulitis (g), and peritubular capillaritis (ptc), with or…
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