2019 American Transplant Congress
Apolipoprotein L1 Genotyping in Potential African American Living Kidney Donors
*Purpose: African Americans(AA) account for 13% of the US population, yet compose more than one third of dialysis patients. Inheriting two Apolipoprotein L1 gene (APOL1)…2019 American Transplant Congress
Adjuvant Immunotherapeutic Approach For Liver Transplant Recipients With Hepatocellular Carcinoma Using Donor Liver Derived Natural Killer Cells
*Purpose: Although liver transplantation (LT) is a preferred treatment for selected patients with Hepatocellular carcinoma (HCC), HCC-recurrence would be a still important medical problem. Most…2019 American Transplant Congress
Solving Target Recognition and Activation Mediated by Non-HLA Agonistic Antibodies Targeting ETAR
*Purpose: Endothelin-1 type A receptor (ETAR) exhibits multiligand binding abilities and may signal upon natural ligand Endothelin-1 (ET-1) and non-HLA ETAR-agonistic IgG (ETAR-IgG)-mediated stimulation similar…2019 American Transplant Congress
A Single-Center Experience with a 6-Month Regimen of Pneumocystis jiroveci Pneumonia Prophylaxis in HIV-Positive Kidney Transplant Recipients
*Purpose: Pneumocystis jiroveci pneumonia (PJP) prophylaxis is recommended for all kidney transplant recipients (KTR) for after transplant. HIV-positive KTRs represent a unique subset, and there…2019 American Transplant Congress
The Impact of Removing DSA as a First Unit of Lung Allocation: Preliminary Results
*Purpose: In an emergency action on November 24, 2017 the Organ Procurement and Transplantation Network (OPTN) altered US lung allocation policy by replacing the donor…2019 American Transplant Congress
Circulating Mirnas Regulate Gene Expression In Kidney Tissue During Transplant Glomerulopathy
1UTHSC, Memphis, TN, 2Albert Einstein College of Medicine, NYC, NY
*Purpose: Post-transplant glomerular disease includes membranous glomerulopathy (MG), secondary or primary focal segmental glomerulosclerosis (FSGS). Furthermore, at post transplant, TG is an important cause of…2019 American Transplant Congress
Predictors and Outcomes of Acute Graft-versus-Host Disease after Liver Transplant
*Purpose: Graft-versus-Host Disease (GVHD) is a rare complication of liver transplant (LT) that has an estimated incidence of 0.1%-2% per year and is associated with…2019 American Transplant Congress
Evaluation of Medication Burden in Kidney Transplant Recipients at Time of Index Hospitalization
*Purpose: This study will assess whether a higher number of medication changes from pre- to post-transplant lead to worse clinical outcomes and higher healthcare utilization…2019 American Transplant Congress
Targeted Proteomic Analysis Detects Acute T Cell-Mediated Kidney Allograft Rejection in Belatacept-Treated Patients
Erasmus MC, Rotterdam, Netherlands
*Purpose: There is an unmet need for reliable minimally-invasive diagnostic biomarkers for immunological allograft monitoring and detection of acute kidney transplant rejection. Here, targeted proteomic…2019 American Transplant Congress
Utilizing Ides To Eliminate Residual Antibodies Targeting Xenografts
Massachusetts General Hospital, Boston, MA
*Purpose: A significant hinderance to the successful use of xenotransplantation has been the presence of preformed antibodies against the donor antigens, known as xenoantigens. Using…
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