ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Case Series Of Total Laparoscopic-hand Assisted Living Donor Right Hepatectomy: First 19 Cases At A Single Center In Usa

    P. N. Martins1, B. Movahedi2, D. Litwin2, A. Bozorgzadeh2

    1Surgery, Division of Transplantation, University of Massachusett, Worcester, MA, 2Surgery, Division of Transplantation, University of Massachusetts, Worcester, MA

    *Purpose: One of the major limitations of living-donor liver donation is the associated morbidity of the procedure. Although left and left-lateral hepatectomy has been performed…
  • 2019 American Transplant Congress

    Store-Operated/Calcium Release Activated Calcium Channel Orai3 is a Novel Target for Immunoregulation

    D. Shankaranarayanan1, M. Lagman1, V. Sharma1, C. Li1, M. Cassidy1, C. Snopkowski1, H. Yang1, T. Muthukumar1, K. Machaca2, M. Suthanthiran1

    1WCMC, New York, NY, 2WCMC, Doha, Qatar

    *Purpose: Store-operated/calcium release activated calcium (CRAC) channels are essential for the signaling of immune cells via calcineurin, a calcium-calmodulin dependent serine-threonine phosphatase. The central importance…
  • 2019 American Transplant Congress

    Murine Cytomegalovirus Infection Down-Regulates Receptor Tyrosine Kinase MerTK on Macrophages to Abrogate Allograft Tolerance

    S. Yu, A. Dangi, M. Burnette, X. Luo

    Division of Nephrology, Department of Medicine, Duke Transplant Center, Duke University Medical Center, Durham, NC

    *Purpose: Cytomegalovirus (CMV) is one of the most common pathogens infecting solid organ transplant recipients. We recently showed that (1) CMV infection impairs the induction…
  • 2019 American Transplant Congress

    Does Proton Pump Inhibitor Use Affect Renal Function in Kidney Transplant Recipients?

    K. Schütte-Nütgen1, D. J. Flothow1, B. Suwelack1, R. Schmidt2, H. Pavenstädt1, S. Reuter1

    1Department of Internal Medicine D, University Hospital Münster, Münster, Germany, 2Institute of Biostatistics and Clinical Research, University Hospital Münster, Münster, Germany

    *Purpose: Recently, proton pump inhibitor (PPI) intake has been linked to acute kidney injury and chronic kidney disease. In the setting of renal transplantation, it…
  • 2019 American Transplant Congress

    Don’t Believe the Hype: Machine Learning-Based Prediction of Kidney Transplant Outcomes

    S. Bae, D. Segev

    Johns Hopkins University, Baltimore, MD

    *Purpose: Machine learning (ML) algorithms may better predict kidney transplant (KT) outcomes at the expense of model interpretability and hypothesis testing. We aimed to compare…
  • 2019 American Transplant Congress

    Risk Factors for Sensitization in the Failing Allograft: A Multi-Center Experience

    M. Lubetzky1, O. Mohammed2, N. Hauser1, R. Friedlander1, V. Sharma1, A. Colovai2, T. Muthukumar1, J. Lee1, E. Akalin2, D. Dadhania1

    1Division of Nephrology, Weil Cornell, New York, NY, 2Division of Nephrology, Montefiore Medical Center, New York, NY

    *Purpose: Sensitization is frequent after an allograft fails and makes re-transplant difficult for many patients.*Methods: We performed a cross-sectional chart review of patients who were…
  • 2019 American Transplant Congress

    Towards 3D-Bioprinting of Bionic Pancreas: Effect of Pressure on the Viability of Pancreatic Islets

    M. Klak, K. Kosowska, E. Majdanska, T. Dobrzanski, A. Berman, L. Kaczynski, P. Kowalska, M. Gomolka, M. Wszola

    Foundation for Research and Science Development, Warsaw, Poland

    *Purpose: 3D bioprinting is the wave of the future in terms of constructing functional, human organs. 3D bioprinting of a bioactive tissue scaffold and Langerhans…
  • 2019 American Transplant Congress

    Acceptability of Animated Video Medium to Educate Kidney Transplant Patients

    K. Bonner, M. Cobler- Lichter, N. Crenesse-Cozien, L. Lewis, T. Feeley, L. Kayler

    University at Buffalo, Buffalo, NY

    *Purpose: Video-based education is an emerging method to address low health literacy, a barrier to informed patient decision-making. A two-dimensional animated educational video was developed…
  • 2019 American Transplant Congress

    Efficacious Home Processing of Urine for Messenger RNA Profiling: A Point-of-Care Approach for Molecular Monitoring of Kidney Transplant Recipients

    C. Snopkowski1, C. Li1, S. Albakry1, B. Botticelli1, M. Cassidy1, J. Lee1, M. Lubetzky1, D. Dadhania1, H. Yang1, R. Ding1, T. Muthukumar1, M. Suthanthiran2

    1WCM, NYC, NY, 2WCM, New York, NY

    *Purpose: Urinary mRNA profiling has been validated in multi-center studies as a robust tool for monitoring kidney transplant recipients. Home processing of urine samples for…
  • 2019 American Transplant Congress

    Near-Infrared Fluorescence Imaging with ZW800-1 Dye to Assess Donor Kidneys While on Ex-Vivo Normothermic Machine Perfusion

    A. S. Arykbaeva1, K. M. Rozenberg2, M. L. Lo Faro2, J. Hunter2, J. B. Doppenberg1, A. R. Valentijn3, A. G. Terwisscha van Scheltinga3, H. Putter4, I. P. Alwayn1, J. V. Frangioni5, J. Burggraaf6, A. L. Vahrmeijer1, R. J. Ploeg2, V. A. Huurman1

    1Department of Surgery, Leiden University Medical Center, Leiden, Netherlands, 2Nuffield Department of Surgical Sciences, Oxford, United Kingdom, 3Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, Netherlands, 4Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, Netherlands, 5Curadel, LCC, Marlborough, MA, 6Centre for Human Drug Research, Leiden, Netherlands

    *Purpose: At present, more older and higher risk donor kidneys are accepted resulting in increased uncertainty about quality. This may result in unjustified discard of…
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