Am J Transplant, Volume 19, Suppl 3 Archives - Page 34 of 214 - ATC Abstracts

2019 American Transplant Congress
Clinical Trial of Allogeneic Islet Transplantation in the Treatment of Diabetes after Renal Transplantation
W. liang, M. Hu, G. Peng, D. Zhou, C. Zeng, W. Zhou, q. Ye, Z. Wang
Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases, Wuhan, China
*Purpose: Diabetes after renal transplantation is one of the most serious complications after renal transplantation. It has a serious impact to the survival of kidney…
2019 American Transplant Congress
Ex Vivo Assessment of Marginal Human Kidneys Using Computed Tomography
M. K. Harris¹, J. R. DiRito², H. Liu³, N. Boutagy³, C. Liu⁴, S. Hosgood², D. Mulligan¹, M. L. Nicholson², A. Sinusas³, D. Haakinson¹, G. T. Tietjen¹
¹Surgery, Yale School of Medicine, New Haven, CT, ²Surgery, University of Cambridge, Cambridge, United Kingdom, ³Yale Translational Research Imaging Center, New Haven, CT, ⁴Radiology, Yale School of Medicine, New Haven, CT
*Purpose: Thousands of ‘marginal’ organs are discarded each year despite a severe organ shortage. This has motivated development of new technologies, such as ex vivo…
2019 American Transplant Congress
Combined Thoracic-Liver Transplants Using Normothermic Machine Perfusion for Liver Preservation: A Case Series
M. Rizzari, K. Crombez, S. Nagai, J. Stracke, A. Al-Kurd, K. Collins, A. Yoshida, M. Abouljoud
Henry Ford Transplant Institute, Detroit, MI
*Purpose: There is minimal data describing combined thoracic-liver transplants (tx) with normothermic machine perfusion (NMP) used for liver preservation as the thoracic tx is done.…
2019 American Transplant Congress
Pluripotent Stem Cell Differentiation: Delaying Forward Differentiation Signals Maintains Definitive Endoderm Phenotype for Cellular Transplantation
J. Fair¹, M. M. Shoja¹, N. Liu¹, I. Patrikeev², M. Motamedi², W. S. Fagg¹
¹Surgery, University of Texas Medical Branch, Galveston, TX, ²Opthalmology and Visual Sciences, University of Texas Medical Branch, Galveston, TX
*Purpose: Endodermal precursors (EP), derived in vitro from mouse pluripotent stem cell (PSC) sources, are capable of clinically useful engraftment in the unmodified (quiescent) liver…
2019 American Transplant Congress
Endogenous Erythropoietin is Required for Spontaneous Acceptance of Murine Renal Allografts
J. Horwitz, P. Cravedi, P. Heeger
Icahn School of Medicine at Mount Sinai, NY, NY
*Purpose: B6 recipients spontaneously accept MHC-disparate renal allografts from allogeneic DBA/2 x B6 (H-2d x H-2b) F1 donors via mechanisms that are in part regulatory…
2019 American Transplant Congress
Novel Insights into Blocking the IL-6 / IL-6 Receptor Pathway after Pig Kidney Xenotransplantation in Baboons
H. Hara¹, G. Zhang¹, H. Iwase¹, T. Yamamoto¹, D. Ayares², D. E. Eckhoff¹, D. K. Cooper¹
¹Surgery, University of Alabama at Birmingham, Birmingham, AL, ²Revivicor Inc., Blacksburg, VA
*Purpose: IL-6 plays an important role in inflammation. The aims of the study were (i) to measure IL-6 in serum in baboons that received IL-6…
2019 American Transplant Congress
Delayed Kidney Transplantation in Combined Liver Kidney Transplantation: A Validation Analysis by the UNOS Registry
L. Chau, M. Safwan, M. Rizzari, K. Collins, A. Yoshida, M. Abouljoud, D. Moonka, S. Nagai
Transplant Surgery, Henry Ford Hospital, Detroit, MI
*Purpose: Delayed kidney transplantation for patients undergoing combined liver-kidney transplant (CLKT) have been suggested to improve patient survival and kidney function compared to simultaneous liver-kidney…
2019 American Transplant Congress
Exploring the Drivers of the Early Decline in One-Year Patient Survival after KAS
K. Lindblad, A. Wilk, D. Stewart
UNOS, Richmnd, VA
*Purpose: The OPTN implemented a new kidney allocation system (KAS) on December 4, 2014, and initial post-implementation monitoring found a statistically significant decline in one-year…
2019 American Transplant Congress
Bortezomib Based Induction Therapy Decreases Delayed Graft Function in High Risk Kidney Transplantation
K. Mahendran¹, N. Koizumi², J. K. Melancon¹
¹Transplant Institute, The George Washington University, Washington, DC, ²Schar School of Policy and Government, George Mason University, Arlington, VA
*Purpose: Over 100,000 candidates await a kidney transplant on the national United Network for Organ Sharing (UNOS) waitlist. Among these candidates, one-third have pre-formed antibodies…
2019 American Transplant Congress
Lower Incidence of Posttransplant Malignancies under Vitamin D (Calcidiol) Treatment in Kidney Transplantation
I. Revuelta¹, V. Tubita², J. Ugalde¹, D. Cucchiari¹, F. Oppenheimer¹, F. Diekmann¹, J. Campistol¹, J. Torregrosa¹
¹Department of Nephrology and Kidney Transplant, Hospital Clinic, Barcelona, Spain, ²Experimental Laboratory of Nephrology and Kidney Transplant, IDIBAPS, Barcelona, Spain
*Purpose: An increasing body of evidence has emerged on the role of 1α,25-dihydroxyvitamin D3[1,25(OH) 2 D] in cell differentiation, which seems to have regulation properties…