Am J Transplant, Volume 19, Suppl 3 Archives - Page 30 of 214 - ATC Abstracts

2019 American Transplant Congress
The Outcomes of Living Donor Kidney Transplantation in Donors or Recipients with Donors’ Renal Arteriosclerotic Lesions on Preoperative Computed Tomography
Y. Miyauchi, T. Noda, N. Miura, T. Kikugawa, T. Saika
Ehime University, Toon, Japan
*Purpose: Living donor kidney transplantation is being increasingly performed with elderly donors. Such elderly donors often have arteriosclerotic lesions (AS) (Figure 1). Whether the outcomes…
2019 American Transplant Congress
Outcomes after Incompatible Living Donor Kidney Transplantation in Older Recipients
J. Long¹, K. Jackson¹, J. Motter¹, S. Bae¹, A. Massie¹, M. Waldram¹, K. Covarrubias¹, J. Chen¹, B. Orandi², N. Desai¹, D. Segev¹, J. Garonzik-Wang¹
¹Johns Hopkins School of Medicine, Baltimore, MD, ²Surgery, University of Alabama at Birmingham, Birmingham, AL
*Purpose: Older individuals are the fastest-growing sub-group of transplant candidates who may face increased risks when considering incompatible living donor kidney transplantation (IKT) due to…
2019 American Transplant Congress
Mitigating Racial and Gender Disparities in Access to Living Donor Kidney Transplantation: Impact of the Nation’s Longest Single-Center Kidney Chain
M. N. Mustian, V. Kumar, K. Stegner, D. Mompoint-Williams, M. Hanaway, M. H. Deierhoi, C. Young, B. Orandi, D. Anderson, P. A. MacLennan, R. D. Reed, B. A. Shelton, D. Eckhoff, J. E. Locke
University of Alabama at Birmingham, Birmingham, AL
*Purpose: Disparities in access to living donor kidney transplantation (LDKT) exist among minorities and women and may be partially explained by antigen sensitization secondary to…
2019 American Transplant Congress
Allograft Quality Impacts Simultaneous Liver Kidney Transplant Survival Outcomes in Recipients That Undergo Liver Re-Transplantation
J. Reyes, M. Eerhart, C. Blanton, P. Chlebeck, E. Polyak, Y. Yankol, L. Fernandez
Department of Surgery, University of Wisconsin - Madison, Madison, WI
*Purpose: The only effective therapeutic strategy for irreversible liver graft failure is re-transplantation. The impact of liver and kidney quality in secondary SLK (sSLK) survival…
2019 American Transplant Congress
Multidisciplinary Practitioner Perspectives on Cardiovascular Disease Guideline Interventions in Liver Transplant Recipients
M. Kosirog¹, L. Adamski¹, A. Daud², D. Finn², D. Gregory¹, D. M. Lloyd-Jones³, J. L. Holl⁴, L. B. VanWagner⁵
¹Medicine-GI & Hepatology, Northwestern University, Chicago, IL, ²Center for Healthcare Studies, Northwestern University, Chicago, IL, ³Medicine-Cardiology and Preventive Medicine, Northwestern University, Chicago, IL, ⁴Pediatrics & Center for Healthcare Studies, Northwestern University, Chicago, IL, ⁵Medicine-GI & Hepatology and Preventive Medicine, Northwestern University, Chicago, IL
*Purpose: Cardiovascular disease (CVD) is a leading cause of mortality in liver transplant recipients (LTRs). However, there is a lack of LT-specific CVD clinical practice…
2019 American Transplant Congress
Totally Robotic Donor Hepatectomy: Feasibility And Early Outcomes
Y. Cheah, C. J. Simon, W. D. Lewis, R. L. Jenkins, M. E. Akoad
Lahey Hospital & Medical Center, Burlington, MA
*Purpose: Robotic surgery is emerging as a surgical technique to enable resection of the liver using minimally invasive techniques; however, very few living donor liver…
2019 American Transplant Congress
Activation of Renal Fibroblasts by Anti- Major Histocompatibility Complex Antibody: A Missing Link in Allograft Fibrosis
M. B. Oliver¹, J. Chen², A. Zmijewska¹, R. B. Mannon¹
¹Medicine, Division of Nephrology, The University of Alabama at Birmingham, Birmingham, AL, ²Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, The University of Alabama at Birmingham, Birmingham, AL
*Purpose: Chronic antibody-mediated rejection (CAMR) is an important contributor to late kidney allograft loss, frequently accompanied by interstitial fibrosis and tubular atrophy. Donor-specific antibodies (DSA)…
2019 American Transplant Congress
Bortezomib Attenuates the Progression of Epithelial to Mesenchymal Transition through Smurf1 Akt mTOR P70S6K Pathway in Rat Allograft Renal Interstitial Fibrosis Model
R. Tan, Z. Wang, S. Fei, Z. Han, J. Tao, X. Ju, M. Gu
No.300 Guangzhou Road of Nanjing, Nanjing, China
*Purpose: Our study was to detect the effects of Bortezomib and Smurf1 in the EMT and allograft renal interstitial fibrosis.*Methods: Biomarkers of EMT, as well…
2019 American Transplant Congress
Deficiency of IRE1a Ameliorates Renal Allograft Injury via Remodeling of Graft-Infiltrating Macrophages
L. Qiu¹, J. Wang¹, X. Yeap¹, S. Han¹, F. Zheng¹, D. Fang², Z. J. Zhang¹
¹Comprehensive Transplant Center, Department of Surgery, Northwestern University, Chicago, IL, ²Department of Pathology, Northwestern University, Chicago, IL
*Purpose: Inflammatory macrophages contribute to the development of ischemia-reperfusion injury (IRI) and allograft rejection. However, the underlying mechanisms by which macrophage mediate allograft injury and…
2019 American Transplant Congress
Comparison of Oral Microbiome in Stable vs Declining Kidney Function in Renal Transplant Recipients
J. Wu¹, A. Muthusamy², G. Al-Ghalith³, B. Wu⁴, B. Guo⁴, W. Guan⁴, D. Knights³, W. Oetting⁵, D. Schladt², R. Remmel⁵, P. Jacobson⁵, A. K. Sharma⁶, A. Matas⁷, A. Israni¹, D. Skaar⁸
¹Nephrology, Hennepin Healthcare, Minneapolis, MN, ²Hennepin Health Research Institute, Minneapolis, MN, ³Computer Science, University of Minnesota, Minneapolis, MN, ⁴Biostatistics, University of Minnesota, Minneapolis, MN, ⁵Pharmacy, University of Minnesota, Minneapolis, MN, ⁶Animal Science, University of Minnesota, Minneapolis, MN, ⁷Surgery, University of Minnesota, Minneapolis, MN, ⁸Denistry, University of Minnesota, Minneapolis, MN
*Purpose: Transplantation causes dysbiosis of the oral microbiome of renal transplant recipients and has been correlated with worse allograft outcomes. We hypothesize that there are…