2019 American Transplant Congress
Incidence and Predictors of Post-Kidney Biopsy (KBx) Bleeding in Liver Transplant (LT) Candidates with Renal Dysfunction
*Purpose: Pre-LT kidney biopsy is seldom performed in LT candidates with renal dysfunction and/or proteinuria partially due to the limited information regarding KBx bleeding. We…2019 American Transplant Congress
Preoperative Risk Factor-based Cardiac Catheterization Is Associated With Low Cardiac Morbidity And Mortality In Liver Transplant Patients
*Purpose: Mortality post-liver transplant historically was largely attributed to coronary artery disease (CAD). Current guidelines recommend screening with non-invasive modalities in patients with risk factors.…2019 American Transplant Congress
Experience With Letermovir Use For The Management Of Cytomegalovirus In Solid Organ Transplant Recipients
*Purpose: Letermovir is a new antiviral recently approved for cytomegalovirus (CMV) prophylaxis in CMV-seropositive hematopoietic-cell transplant recipients. Its off-label use in solid organ transplant (SOT)…2019 American Transplant Congress
CCR5-Mediated Recruitment of NK Cells to the Kidney is a Critical Step for Host Defense to Candida albicans Infection
*Purpose: Candida albicans infection causes a high rate of mortality in immunocompromised or transplant patients. In this study, we investigated the role of CCR5 that…2019 American Transplant Congress
Impact of a Short Duration, Narrow Spectrum Perioperative Antibiotic Prophylaxis Regimen on Multi-Drug Resistant Surgical Site Infections in Adult Orthotopic Liver Transplantation
*Purpose: There is a paucity of data defining the optimal agent and timing of peri-operative antimicrobial prophylaxis in orthotopic liver transplantation (OLT). The purpose of…2019 American Transplant Congress
Long Term Cold Ischemia Time in Kidney Transplantation. The Role of Hypothermic Machine Perfusion
*Purpose: Hypothermic machine perfusion (HMP) of deceased donor kidneys is associated with a better outcome than static cold storage (SCS). Aim of this prospective study…2019 American Transplant Congress
Impact of an Intra-Abdominal Cooling Device during Open Kidney Transplantation in Pigs
*Purpose: Renal transplantation is the preferred treatment for end-stage renal disease. Currently, there is a large gap between the supply and demand for transplantable kidneys.…2019 American Transplant Congress
Viability Testing and Transplantation of Marginal Donor Livers (VITTAL) Trial Outcomes: Proteomic Analysis of Perfusates from Livers Undergoing Normothermic Machine Liver Perfusion Reveals Biomarkers Predictive of Graft Viability and Post-Transplant Complications
*Purpose: The VITTAL clinical trial demonstrated that post-ischaemic normothermic machine perfusion(NMP) can increase utilisation of livers from the marginal pool of extended criteria donors (ECD).…2019 American Transplant Congress
ICOS+PD-1+ Circulating T Follicular Helper Cells Are a Biomarker of Humoral Alloreactivity and Predict Donor-Specific Antibody Generation Following Transplantation
Emory Transplant Center, Atlanta, GA
*Purpose: Mounting evidence in kidney transplantation suggests that donor-specific antibodies (DSA) significantly contribute to renal allograft loss. However, biomarkers to guide clinical management of DSA…2019 American Transplant Congress
Donor-Recipient HLA Mismatched Peptides Calculated by PIRCHE Algorithm Associate with De Novo Donor-Specific Cellular and Humoral Alloreactivity and Predicts Inferior Graft Outcome
*Purpose: PIRCHE-II algorithm predicts mismatched donor-derived HLA peptides number presented on recipient HLAclass-II molecules to recipient T-cells (indirect pathway of allorecognition) and has been associated…
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