Am J Transplant, Volume 19, Suppl 3 Archives - Page 22 of 214 - ATC Abstracts

2019 American Transplant Congress
Analysis of Lactic Acid Response in Renal Transplant Patients
A. A. Henderson¹, H. Ahmed², M. R. Wakefield¹
¹Surgery/Urology, University of Missouri School of Medicine, Columbia, MO, ²University of Missouri School of Medicine, Columbia, MO
*Purpose: Lactic acid (LA) serves as an important biomarker in the evaluation of ischemia, sepsis, metabolic acidosis, and trauma. During renal transplantation (RT), there is…
2019 American Transplant Congress
Utility of a Novel dd-cfDNA Test to Detect Injury in Renal Post-Transplant Patients
J. Peabody¹, P. Billings², Z. Demko², D. Paculdo¹, M. Tran¹, S. Moshkevich², C. Valdenor¹
¹QURE Healthcare, San Francisco, CA, ²Natera, Inc., San Carlos, CA
*Purpose: Detecting allograft injury and rejection is critical to preventing graft loss. Current standard of care (SoC) relies on serum creatinine (SC) and biopsy to…
2019 American Transplant Congress
Effect of Renal Function on Asymmetric Dimethylarginine (ADMA) Homeostasis in Kidney Donors and Recipients
M. Y. Said¹, R. M. Douwes¹, M. van Londen¹, I. Minović¹, A. Frenay², M. H. de Borst¹, E. van den Berg¹, M. R. Heiner-Fokkema³, A. A. Kayacelebi⁴, A. Bollenbach⁴, H. van Goor⁵, G. J. Navis¹, D. Tsikas⁴, S. J. Bakker¹
¹Internal medicine, University Medical Center Groningen, Groningen, Netherlands, ²Gynecology and Obstetrics, Amsterdam University Medical Center, Amsterdam, Netherlands, ³Laboratory Medicine, University Medical Center Groningen, Groningen, Netherlands, ⁴Inst. of Toxicology, Core Unit Proteomics, Hannover Medical School, Hannover, Germany, ⁵Pathology and Medical Biology, University Medical Center Groningen, Groningen, Netherlands
*Purpose: ADMA is a methylated form of arginine and an endogenous nitric oxide synthase inhibitor. Plasma ADMA (pADMA) is known as a strong cardiovascular risk…
2019 American Transplant Congress
Partial Parathyroidectomy And Allograft Function In Renal Transplant Patients
M. Gao¹, E. Vilayur¹, D. Ferreira², C. Bendinelli¹, C. Sankoorikal¹
¹John Hunter Hospital, New Lambton Heights, Australia, ²Liverpool Hospital, Liverpool, Australia
*Purpose: Studies have previously shown that total parathyroidectomy in the renal transplant patient may adversely affect allograft function. The primary aim of this study was…
2019 American Transplant Congress
Long-term Impact of Antihypertensive Treatment and Tacrolimus Dose in Renal Allograft Recipients 5 Years Post-Transplantation
D. Rush¹, S. Cockfield², S. Wilson³, J. Schwartz⁴
¹University of Manitoba, Winnipeg, MB, Canada, ²University of Alberta Hopspital, Edmonton, AB, Canada, ³Astellas Pharma Global Development, Northbrook, IL, ⁴Astellas Pharma US, Northbrook, IL
*Purpose: Inflammation and fibrosis after renal transplantation may be modulated by optimizing tacrolimus exposure, or by use of angiotensin-converting enzyme inhibitors (ACEi), or angiotensin receptor…
2019 American Transplant Congress
The Utility of Donor and Recipient BK Virus Antibody Testing Prior to Renal Transplantation in Risk Assessment for Developing BK Viremia
N. Donmez, S. I. Al-Akash
Driscoll Children's Hospital, Corpus Christi, TX
*Purpose: The correlation between donor (DON) and recipient (REC) BKV antibody (AB) titers and BK viremia in renal transplant (RTx) has not been well-studied in…
2019 American Transplant Congress
Cytokine Profiles in Children after Pediatric Kidney Transplantation with Acute Cellular Compared to Chronic Active Antibody-Mediated Rejection
N. Borsum, T. Ahlenstiel-Grunow, L. Pape
Pediatric Nephrology, Hannover Medical School, Hannover, Germany
*Purpose: Until now, no blood biomarkers have been identified to enable early diagnosis of acute cellular or chronic active antibody-mediated rejection (cABMR) after pediatric kidney…
2019 American Transplant Congress
Tandem Mass Tags Based Liquid Chromatography/ Mass Spectrometry Analysis of Quantitative Proteomic Changes in Renal Allograft Biopsies with Polyomavirus BK Nephropathy
F. Fang, P. Liu, L. Song, Y. Zhao, G. Zeng, G. Tseng, K. Xiao, P. Randhawa
University of Pittsburgh, Pittsburgh, PA
*Purpose: Transcriptomics analyses have not generated reliable means to distinguish T-cell mediated rejection (TCMR) from BK virus nephropathy (BKVN). Proteomics-based approaches deserve further exploration since…
2019 American Transplant Congress
Donor Hepatitis C Seropositivity Confers Poorer Post-transplant Outcomes In Recipients Of Marginal Livers In The Post-hepatitis C Treatment Era
M. B. Shah, M. Gupta, X. Mei, R. Gedaly
University of Kentucky, Lexington, KY
*Purpose: Since the introduction of newer antiretroviral therapies, utilization of hepatitis C (HCV) positive livers has increased significantly for HCV recipients. In an effort to…
2019 American Transplant Congress
Increasing the Number of Liver Transplants through Active Review of Offers Turned Down
M. L. Melcher, C. A. Bonham, A. Gallo, W. Concepcion, I. Jacobson, C. O. Esquivel
Stanford University, Palo Alto, CA
*Purpose: To increase the number of patients benefiting from a liver transplant, a university transplant program instituted a weekly review meeting of the transplant surgeons…