2019 American Transplant Congress
Regional Disparities In The Transplant Rates Across Unos Regions Pre- And Post-kidney Allocation System Policy Implementation
Massachusetts General Hospital, Boston, MA
*Purpose: Geographic distribution of organs for transplant is a critical component of the Organ Procurement and Transplantation Network (OPTN) policies. However, there is no single…2019 American Transplant Congress
Safety and Efficacy of Imlifidase in Highly-Sensitized Kidney Transplant Patients: Results from a Phase 2 Study
*Purpose: Many patients eligible for kidney transplantation are sensitized to allo-HLA antigens and face prolonged waiting times and increased mortality. The presence of donor specific…2019 American Transplant Congress
Early Tacrolimus Trough Concentration Variability Could Predict Rejection in Pediatric Liver Transplantation: A Single-Center and Retrospective Research
Renji Hospital, Shanghai, China
*Purpose: With great development in immunosuppressive therapy, the long-term outcomes and survival time in patients who received solid organ transplantation have been improved remarkably. The…2019 American Transplant Congress
Endothelial Cell Replacement – A Closer Step to Personalized, Tissue-Engineered Transplants
Rabin Medical Center, Petah-Tiqwa, Israel
*Purpose: Whole organ perfusion decellularization has been proposed as a promising method for the generation of non-immunogenic organs from allogeneic or xenogeneic donors. However, the…2019 American Transplant Congress
Sirna Uptake During Ex Vivo Hypothermic And Normothermic Liver Machine Perfusion: Beginning Of A New Era Of Organ Preservation
*Purpose: RNA interference (RNAi) is a natural gene modulation process that was recently approved for clinical use and has great potential for treatment of many…2019 American Transplant Congress
Identification and Determinants of Cardiac Allograft Vasculopathy Trajectories after Heart Transplantation
*Purpose: CAV is a major contributor of heart transplant recipient’s mortality. However, little is known about CAV long-term evolution profiles and their determinants. Such information…2019 American Transplant Congress
Eculizumab Deposition in Renal Transplants
*Purpose: Eculizumab is a recombinant humanized IgG monoclonal antibody that inhibits C5, thereby preventing the activation of C5a and formation of membrane attack complex C5b-C9.…2019 American Transplant Congress
External Validation of the Living Kidney Donor Profile Index (LKDPI) in the Canadian Kidney Transplant Recipient Population
*Purpose: The LKDPI is a risk index which incorporates clinical characteristics of living kidney donors and their recipients to predict the risk of total graft…2019 American Transplant Congress
A Priori Identification of Hard-to-Place Livers
1SRTR, Minneapolis, MN, 2OPTN, Richmond, VA, 3SRTR, Mineeapolis, MN
*Purpose: Identification of hard-to-place deceased donor livers is important due to its potential role in expedited placement. Determining hard-to-place must be based on data available…2019 American Transplant Congress
The mIR17-92 Cluster Promotes Costimulation Resistant Effector Memory T Cell-Mediated Alloresponses
1Surgery, Duke University, Durham, NC, 2Immunology, Duke University, Durham, NC
*Purpose: CD57 expression has been shown to identify a subset of memory T cells that are resistant to CD28/B7 costimulation blockade (B7CoB). This study was…
American Transplant Congress abstracts