ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Whole Body CT Imaging in Deceased Donor Screening

    J. W. Mensink1, R. A. Pol.2, W. N. Nijboer1, J. de Jonge3, K. M. Ooms - de Vries4, M. F. van der Jagt5, M. C. van de Poll6, I. P. Alwayn1, A. E. Braat1

    1Department of Surgery; Division of Transplantation, Leiden University Medical Center, Leiden, Netherlands, 2Department of Surgery; Division of Transplantation, University Medical Center Groningen, Groningen, Netherlands, 3Department of Surgery; Division of Transplantation, Erasmus Medical Center, Rotterdam, Netherlands, 4Dutch Transplant Foundation, Leiden, Netherlands, 5Department of Surgery; Division of Transplantation, University Medical Center St. Radboud, Nijmegen, Netherlands, 6Department of Surgery and Department of Intensive Care, Maastricht University Medical Center, Maastricht, Netherlands

    *Purpose: Using older (extended criteria) donors to increase the donor pool increases the risk of malignancies in the donor. Our aim was to analyze the…
  • 2019 American Transplant Congress

    Biomarkers in Multivisceral and Intestinal Transplantation

    D. A. Cheung1, J. Garcia1, T. Beduschi2, A. H. Langshaw1, K. L. Arheart3, I. A. Gonzalez4

    1Pediatric Gastroenterology, University of Miami, Miami, FL, 2Surgery, Division of Liver/GI Transplant, University of Miami, Miami, FL, 3Public Health Sciences, Division of Biostatistics, University of Miami, Miami, FL, 4Pediatric Infectious Diseases and Immunology, University of Miami, Miami, FL

    *Purpose: Multivisceral transplant (MVT) and isolated intestinal transplant (ITx) are complex surgical procedures that result in a pro-inflammatory state, making interpretation of biomarkers in the…
  • 2019 American Transplant Congress

    Willingness to Acquire Donor-Derived Hepatitis C Infection May Reduce Waitlist Mortality for Heart Transplant Candidates

    B. E. Lonze, A. Reyentovich, N. Moazami, D. E. Smith, C. Gidea, R. A. Montgomery

    NYU Langone Transplant Institute, New York, NY

    *Purpose: Hearts from deceased donors with hepatitis C infection (HCV+) are disproportionately discarded because most waitlist registrants are HCV negative (HCV-). For some with end-organ…
  • 2019 American Transplant Congress

    Pathologic Vascular Invasion Correlates with Worse Outcome in Hepatoblastoma Patients Treated with Liver Transplantation – A Hepatoblastoma Transplant Consortium Study

    T. H. Malik1, H. Zhu2, T. Ha3, S. Commander4, C. Trautz5, R. Sindhi5, S. Kim6, K. Vakili6, N. Vachharajani7, W. Chapman7, A. Griesemer8, M. Martinez8, J. A. Goss9, S. Vasudevan10

    1Baylor College of Medicine, Houston, TX, 2Texas Children's Hospital, Houston, TX, 3Department of Surgery, Baylor College of Medicine, Houston, TX, 4Department of Surgery, Duke University School of Medicine, Durham, NC, 5Department of Surgery, University of Pittsburgh, Pittsburgh, PA, 6Department of Surgery, Boston Children's Hospital, Boston, MA, 7Department of Surgery, Washington University School of Medicine in St. Louis, St. Louis, MO, 8Department of Surgery, NewYork-Presbyterian Morgan Stanley Children's Hospital, New York, NY, 9Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX, 10Department of Pediatric Surgery, Texas Children's Hospital, Houston, TX

    *Purpose: Orthotopic liver transplant (OLTx) is the most common method to treat unresectable hepatoblastoma (HB) in children. There is limited data focusing on the outcomes…
  • 2019 American Transplant Congress

    The Important Roles of Dendritic Cells in Transplantation

    T. Ueno1, M. M. McGrath1, M. Y. Yeung1, S. Cai1, Y. Ueno1, T. Yokoyama2, Y. Kihara2, O. Konno2, Y. Nakamura2, H. Iwamoto2, A. K. Chandraker1

    1Medicine, Renal Division, Brigham and Women's Hospital, Transplantation Research Center, Boston, MA, 2Kidney Transplantation Surgery, Tokyo Medical University, Hachioji Medical Center, Tokyo, Japan

    *Purpose: The interplay between dendritic cells (DCs) and T cells plays a central role in the process of allograft rejection. Upon antigen exposure, positive costimulatory…
  • 2019 American Transplant Congress

    Full and Sustained Donor Hematopoietic Chimerism after an Isolated Kidney Transplantation

    J. Zuber1, O. Boyer1, B. Neven1, E. Six2, R. Berthaud1, M. Ould Rabah1, S. Sobrino2, C. Lagresle2, I. André-Schmutz2, M. Cavazzana1, S. Blanche1, R. Salomon1

    1Paris Descartes University, Paris, France, 2Inserm UMRS 1163, Paris, France

    *Purpose: Full donor chimerism was reported three times in the absence of myelosuppressive regimen, only after liver or multivisceral transplantation, but never after kidney transplantation.…
  • 2019 American Transplant Congress

    Increased Frequency of Myeloid-Derived Suppressor Cells Contributing to Prolong Skin Allograft Survival in Aged Mice

    W. Lee, Y. Wang, T. Wu, C. Cheng, C. Lee, T. Wu, H. Chou, K. Chan

    General Surgery, Chang-gung Hospital, Taoyuan, Taiwan

    *Purpose: Currently, aged people are increasing and more and more aged people have organ transplantation. The immunity in aged people is weaker than young people.…
  • 2019 American Transplant Congress

    Generation of Human/Pig Hybrid Thymus to Achieve Immune Tolerance to Pig Antigens with Optimal Immune Function

    M. Khosravi Maharlooei, H. Li, M. Holzl, A. Vecchione, A. Misra, A. Ruiz, R. Madley, G. Nauman, N. Danzl, G. Zhao, K. Yamada, M. Sykes

    Columbia University, New York, NY

    *Purpose: Thymus transplantation is a promising approach to induce T-cell tolerance for xenotransplantation. We have previously shown that humanized mice generated with human hematopoietic stem…
  • 2019 American Transplant Congress

    De Novo Complement-Activating Donor Specific Antibodies in Pediatric Renal Transplant Recipients Are Highly Responsive to Therapy

    V. Sigurjonsdottir, A. Chaudhuri, P. Grimm

    Pediatric Nephrology, Stanford, Los Altos, CA

    *Purpose: Antibody mediated rejection remains a common cause for pediatric renal allograft loss. After recognizing that graft failure was more common in our pediatric renal…
  • 2019 American Transplant Congress

    Regional Disparities In The Transplant Rates Across Unos Regions Pre- And Post-kidney Allocation System Policy Implementation

    A. C. Perez-Ortiz, E. Heher, N. Elias

    Massachusetts General Hospital, Boston, MA

    *Purpose: Geographic distribution of organs for transplant is a critical component of the Organ Procurement and Transplantation Network (OPTN) policies. However, there is no single…
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