Am J Transplant, Volume 19, Suppl 3 Archives - Page 202 of 214 - ATC Abstracts

2019 American Transplant Congress
Outcomes of Adult Lung Transplant Recipients of Donation after Circulatory Death Allografts in the US
W. S. Cherikh¹, J. Stehlik², A. Sadavarte¹, D. Van Raemdonck³
¹United Network for Organ Sharing, Richmond, VA, ²University of Utah School of Medicine, Salt Lake City, UT, ³University Hospitals Leuven, Leuven, Belgium
*Purpose: This analysis was performed to compare outcomes of adult lung (LU) transplant (TX) recipients of donation after circulatory death (DCD) and donation after brain…
2019 American Transplant Congress
Donor Derived Cell Free DNA Initiates De-Novo Donor Specific Antibody (DSA) Responses
S. Jordan¹, D. Sawinski², S. Dholakia³
¹Cedars-Sinai, Los Angeles, CA, ²Hospital of the University of Pennsylvania, Philadelphia, PA, ³CareDx, Brisbane, CA
*Purpose: We hypothesize that subclinical inflammation, resulting in molecular injury, may contribute to sensitization of the recipients’ immune system. Antigenic presentation of donor-derived nucleic acids,…
2019 American Transplant Congress
Machine Perfusion Allows Use of High KDPI and Prolonged Cold Ischemia Time in Deceased Donors: A Single Center Effort to Decrease Discard Rates
M. Ortigosa-Goggins, J. Gaynor, A. Mattiazzi, J. Figueiro, G. Burke, G. Ciancio, G. Guerra
Miami Transplant Institute, University of Miami, Miami, FL
*Purpose: Discard rates of deceased donor kidney transplants(DDKT)rises as the kidney donor profile index(KDPI)increases,and approaches 60%for KDPI of >85%.Pulsatile machine perfusion(MP)allows use of kidneys with…
2019 American Transplant Congress
The Outcomes after an Infection in Older Liver Transplant Recipients is Comparable to Younger Adults
J. Garcia-Diaz¹, M. Kerkelis², T. Shah³, M. Tucker⁴, M. Gastanaduy⁵, J. Woo¹, M. Ponder¹, M. Malinis⁶, M. Malinis⁶
¹Infectious Diseases, Ochsner Medical Center, New Orleans, LA, ²University of Queensland/Ochsner Clinical School, New Orleans, LA, ³Internal Medicine, St. Joseph Hospital, Denver, CO, ⁴Internal Medicine, Yale School of Medicine, New Haven, CT, ⁵Center for Outcomes and Health Services Research, Ochsner Medical Center, New Orleans, LA, ⁶Infectious Diseases, Yale School of Medicine, New Haven, CT
*Purpose: Solid organ transplantation is being increasingly offered to older patients with concurrent chronic medical conditions such as cardiovascular, cerebrovascular, and renal disease. Risk of…
2019 American Transplant Congress
Super-resolution Evaluation Of The Glomerular Basement Membrane Changes In The Course Of Transplant Glomerulopathy
D. Hammad, J. H. Miner, T. Alhamad, H. Suleiman
Washinton University in St. Louis, St. Louis, MO
*Purpose: Transplant Glomerulopathy (TG) is a histologic entity that affects around 20% of kidney allografts by 5 years post transplantation and results in a significant…
2019 American Transplant Congress
The Role of CD47/SIRPα and CD47/TSP-1 Pathways in Pig-to-Baboon Kidney Transplantation Using hCD47 Transgenic Kidneys
K. Takeuchi¹, Y. Ariyoshi¹, T. Pomposelli¹, L. Boyd¹, D. Ekanayake-Alper¹, S. Arn¹, R. Hawley¹, D. Ayares², M. Lorber³, M. Sykes¹, D. Sachs¹, R. Johnson⁴, K. Yamada¹
¹CCTI/Surgery, Columbia University Medical Center, New York, NY, ²Revivicor Inc., Blacksburg, VA, ³Lung BioTechnology PBC, Silver Spring, MD, ⁴Division of Renal Diseases and Hypertension, University of Colorado, Aurora, CO
*Purpose: We have recently reported that both CD80 upregulation and the degradation of SMPDL-3b on glomerular podocytes are involved in the development of post kidney…
2019 American Transplant Congress
Increased Access to Transplantation for Medicaid Patients Following Medicaid Expansion
A. Massie, M. Henderson, T. Hwee, D. Segev
Johns Hopkins, Baltimore, MD
*Purpose: Under the Patient Protection and Affordable Care Act (ACA), states in the United States had the option of expanding Medicaid eligibility. 24 states adopted…
2019 American Transplant Congress
Facial Composite Tissue Allotransplantation: First Canadian Experience
S. Collette¹, A. Govshievich², S. F. Dufresne¹, D. Désy¹, H. St-Jacques¹, D. Borsuk¹
¹Hopital Maisonneuve-Rosemont, Montreal, QC, Canada, ²University of Montreal, Montreal, QC, Canada
*Purpose: Facial vascularized composite allotransplantation (VCA) has emerged as a groundbreaking reconstructive solution for patients with severely disfiguring facial injuries. It allows simultaneous “like with…
2019 American Transplant Congress
Impact of Belatacept Conversion on Renal Function, Histology and Gene Expression in Kidney Transplant Patients with Chronic Active Antibody-Mediated Rejection
D. Kumar¹, M. Raynaud², P. Halloran³, A. Loupy², J. Chang³, J. Reeve³, I. Yakubu¹, S. Bobba¹, L. Kamal¹, M. Levy¹, C. Bhati¹, P. Kimball¹, A. King¹, G. Gupta¹
¹Virginia Commonwealth University, Richmond, VA, ²Paris Transplant Group, Paris, France, ³Alberta Transplant Genomics Applied Centre, Edmonton, AB, Canada
*Purpose: Chronic active antibody mediated rejection (cABMR) is a major cause of long-term kidney transplant (KT) loss. Current therapies have unclear efficacy and significant side…
2019 American Transplant Congress
Preemptive Therapy is Cost Effective When Compared to Prophylaxis in Cytomegalovirus Donor Positive – Recipient Negative Liver Transplant Recipients
M. M. Wagener¹, D. J. Winston², R. R. Razonable³, G. M. Lyon III⁴, F. P. Silveira⁵, A. P. Limaye⁶, N. Singh¹
¹ID, U Pittsburgh and VAPHS, Pittsburgh, PA, ²ID, UCLA, Los Angeles, CA, ³ID, Mayo Clinic, Rochester, MN, ⁴ID, Emory, Atlanta, GA, ⁵ID, U Pittsburgh, Pittsburgh, PA, ⁶ID, U Washington, Seattle, WA
*Purpose: To compare the cost effectiveness of preemptive therapy (PET) vs prophylaxis for the prevention of cytomegalovirus (CMV) in high-risk donor seropositive/recipient seronegative (D+R-) liver…