ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Unifying Interpretation of Molecular HLA Typing Data between the Solid Organ Allocation Match Run and Virtual Crossmatch

    N. Kaur1, E. Kransdorf2, M. Pando3, L. Gragert1

    1Tulane University School of Medicine, New Orleans, LA, 2Cedars-Sinai Heart Institute, Los Angeles, CA, 3Baylor Scott & White, Temple, TX

    *Purpose: Virtual crossmatch compares a transplant candidate’s HLA antibody assay results to the HLA typing of the donor before an organ offer is accepted. While…
  • 2019 American Transplant Congress

    Use of mTOR Inhibitors in Hypersensitized Kidney Transplant Recipients: Breaking False Myths

    D. Cucchiari1, A. Molina-Andujar1, E. Montagud-Marrahi1, F. J. Centellas-Pérez2, I. Revuelta1, F. Oppenheimer1, F. Diekmann1

    1Renal Transplant Unit, Hospital Clínic, Barcelona, Spain, 2Complejo Hospitalario Universitario, Albacete, Spain

    *Purpose: Many centers avoid the use of mTOR inhibitors (mTORi) in hypersensitized kidney transplant recipients and usually employ an immunosuppression based on Mycophenolic Acid (MPA),…
  • 2019 American Transplant Congress

    Dosing Requirements Of Astagraf Xl In African American Kidney Transplant Recipients Converted From Twice-daily Tacrolimus (aaaktrs)

    J. N. Fleming, M. A. Posadas-Salas, D. J. Taber

    Medical University of South Carolina, Charleston, SC

    *Purpose: Pharmacokinetics from clinical studies demonstrated similar drug exposure (AUC) and correlation between trough (C0) and AUC between tacrolimus IR and Astagraf XL, which led…
  • 2019 American Transplant Congress

    Impact of Tacrolimus Formulation on Tacrolimus Level Coefficient of Variations

    S. January1, T. Horwedel2, J. Hagopian1, C. Carthon1, A. Gharabagi3, R. Delos Santos4

    1Barnes-Jewish Hospital, Saint Louis, MO, 2Veloxis Pharmaceuticals, Inc., Cary, NC, 3Saint Louis College of Pharmacy, Saint Louis, MO, 4Washington University School of Medicine, Saint Louis, MO

    *Purpose: Increased coefficient of variation (CV) of tacrolimus (FK) levels, indicating high intra-patient FK level fluctuations, are associated with increased rejection, development of donor-specific antibodies,…
  • 2019 American Transplant Congress

    Outcomes for Liver Transplant Recipients on Renal Replacement Therapy: Who Cannot Wait for Safety Net

    A. Pita1, N. Kaur1, M. Lo2, A. F. Sabour1, V. Tristan1, Y. Genyk1, M. K. Nadim3, L. Sher1

    1Department of Surgery, Keck Medical Center of USC, Los Angeles, CA, 2Department of Preventive Medicine, Keck Medical Center of USC, Los Angeles, CA, 3Department of Medicine, Keck Medical Center of USC, Los Angeles, CA

    *Purpose: The purpose of this study is to identify risk factors for poor outcomes for liver transplant (LT) recipients on renal replacement therapy (RRT) in…
  • 2019 American Transplant Congress

    Early Achievement of Sustained Virological Response in Liver Transplant Recipients with Hepatitis C Reduces Risks of End Stage Renal Disease

    M. Yoshikawa1, T. Fukumoto2

    1Nephrology, Kobe University Hospital, Kobe, Japan, 2Hepato-Biliary-Pancreas Surgery, Kobe University Hospital, Kobe, Japan

    *Purpose: Chronic kidney disease (CKD) is common after liver transplantation (LT) and result worse morbidity and mortality. Hepatitis C virus (HCV) infection is recognized as…
  • 2019 American Transplant Congress

    Outcomes of Side-to-Side Cavocavostomy versus Traditional Piggyback Implantation in Liver Transplantation

    T. Lee, V. Dhar, M. Morris, L. Winer, A. Cortez, L. Sage Silski, M. Cuffy, T. Diwan, R. Quillin, III, S. Shah

    University of Cincinnati, Cincinnati, OH

    *Purpose: Side-to-side cavocavostomy (STSCC) is an alternative caval sparing implantation technique for liver transplantation (LT), but despite its technical ease compared to traditional piggyback (TP)…
  • 2019 American Transplant Congress

    Incidence of Cytomegalovirus in Moderate Risk Kidney Transplant Recipients Receiving Low Dose Valganciclovir

    T. Fallah1, A. Logan2, L. Beltran Garcia3, L. Bowman2

    1Hospital of the University of Pennsylvania, Philadelphia, PA, 2Tampa General Hospital, Tampa, FL, 3Florida Kidney Physicians, Tampa General Hospital, Tampa, FL

    *Purpose: Studies evaluating the efficacy of valganciclovir (VGC) at 450 mg daily versus 900 mg daily for the prevention of cytomegalovirus (CMV) in kidney transplant…
  • 2019 American Transplant Congress

    Outbreak of Pneumocystis Pneumonia in a Transplant Center Linked to a Single Genotype of Pneumocystis jirovecii: Effects of Cytomegalovirus Infection and Allograft Rejection

    S. Hosseini-Moghaddam1, S. Dufresne2, M. Shokoohi3, G. Singh1, E. HunterGutierrez1, P. Dufresne2, A. House1, P. Luke1, A. Nagpal1, P. Marotta1, A. Humar4, A. Jevnikar1, D. Kumar4

    1Western University,LHSC,University Hospital, London, ON, Canada, 2Maisonneuve-Rosemont Hospital,Université de Montréal, Montreal, QC, Canada, 3Epidemiology and Biostatistics, Western University, London, ON, Canada, 4University of Toronto, University Health Network, Toronto General Hospital, Toronto, ON, Canada

    *Purpose: Although post-transplant pneumocystis pneumonia (PCP) outbreaks have been reported from Asia, Australia and Europe, there are limited data from North America. We investigated transmissibility…
  • 2019 American Transplant Congress

    Daptomycin Perioperative Prophylaxis for Prevention of Vancomycin-Resistant Enterococcus Infection in VRE-Colonized Liver Transplant Recipients during the Early Post-Transplant Period

    S. Sarwar, S. Gleeson, M. Malinis, M. M. Azar

    Section of Infectious Diseases, Department of Medicine, Yale School of Medicine, New Haven, CT

    *Purpose: Antibiotic prophylaxis for enteric pathogens is recommended before liver transplantation (LT). Perioperative screening protocols and antimicrobials vary between institutions. Some institutions that do not…
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