ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Pre-Liver Transplant Renal Dysfunction is an Independent Predictor of Post-Liver Transplant Return to the Operating Room

    H. M. Wadei, M. L. Mai, C. Taner, A. P. Keaveny, S. Mao, P. Abader, P. Kroner, K. Croome

    Department of Transplant, Mayo Clinic, Jacksonville, FL

    *Purpose: Pre-liver transplant (LT) renal dysfunction predicts worse outcomes post-LT but the reasons for this are unclear. We aimed at identifying the effect of pre-LT…
  • 2019 American Transplant Congress

    Higher Population Donor Service Areas Are Associated With Lower Meld At Death On Wait List And Higher Meld At Removal For “Too Sick

    Y. Hung, Y. Bababekov, C. Rickert, Y. Hsu, D. Chang, H. Yeh

    Massachusetts General Hospital, Boston, MA

    *Purpose: Plans for distance based allocation in liver transplantation have raised concerns that patients listed in more rural Donor Service Areas (DSAs) will be disadvantaged…
  • 2019 American Transplant Congress

    Comparison of Two Dosing Regimens of Valganciclovir for Cytomegalovirus Prophylaxis in High-Risk Liver Transplant Recipients

    A. L. Bixby, L. Fitzgerald, L. Cotiguala, J. M. Park, D. Kaul, C. Sonnenday, S. Tischer

    Michigan Medicine, Ann Arbor, MI

    *Purpose: Significant controversy surrounds the optimal dose and duration of valganciclovir (VGCV) to prevent CMV in high-risk (D+/R-) liver transplant (LT) recipients. High doses cause…
  • 2019 American Transplant Congress

    Is Exposure to Wildfires Associated with Invasive Fungal Infections?

    J. S. Mulliken1, A. G. Rappold2, M. Fung1, J. M. Babik1, S. B. Doernberg1

    1Division of Infectious Diseases, University of California San Francisco, San Francisco, CA, 2National Health and Environmental Effects Research Laboratory, United States Environmental Protection Agency, Durham, NC

    *Purpose: In recent decades, climate change and other factors have led to a global increase in wildfires. After a large fire in Northern California in…
  • 2019 American Transplant Congress

    Efficacy of Filgrastim in Solid Organ Transplant Recipients

    M. Spinner1, K. Gaffney1, S. Gundling2

    1Pharmacy, Cleveland Clinic, Cleveland, OH, 2University of Pittsburgh School of Pharmacy, Pittsburgh, PA

    *Purpose: Neutropenia frequently occurs after solid organ transplantation (SOT) due to immunosuppression, antiviral prophylaxis, or viral infections. Immunosuppression reduction or antiviral prophylaxis minimization can lead…
  • 2019 American Transplant Congress

    Treprostinil Attenuates Renal Ischemia-Reperfusion Injury in Rat

    M. Ding1, E. Tolbert2, M. Birkenbach3, C. Chung4, R. Gohh5, F. Akhlaghi1, N. Ghonem1

    1Biomedical and Pharmaceutical Sciences, URI, Kingston, RI, 2Nephrology, Rhode Island Hsopital, Providence, RI, 3Pathology, Rhode Island Hospital, Providence, RI, 4Surgery, Rhode Island Hospital, Providence, RI, 5Organ Transplantation, Rhode Island Hospital, Brown University, KINGSTON, RI

    *Purpose: Kidney transplantation (KTx) is the optimal treatment for end-stage renal diseases. The surgical procedure of KTx inherently requires cold ischemic preservation and warm reperfusion…
  • 2019 American Transplant Congress

    Microvascular Rarefaction and Long-Term Graft Dysfunction in Kidney Transplant Recipients with Delayed Graft Function

    A. Doreille, S. Larivière-Beaudoin, A. Karakeussian-Rimbaud, M. Hébert, M. Dieudé, N. Patey, H. Cardinal

    1Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal, QC, Canada

    *Purpose: Delayed graft function (DGF), or acute kidney injury in the perioperative period, is associated with decreased kidney graft survival.*Methods: As animal studies suggest that…
  • 2019 American Transplant Congress

    The Molecular Profile of Kidney Allografts Unveil Specific Biomarkers for Subclinical Acute Rejection (SAR). Towards an Early Detection and a Targeted Treatment

    S. N. Cox, S. Chiurlia, F. P. Schena

    Schena Foundation, Valenzano-Bari, Italy

    *Purpose: SAR diagnosed by protocol biopsy is an independent risk factor for chronic allograft injury. We organized a molecular study on 24 AB0 compatible cadaveric…
  • 2019 American Transplant Congress

    Post-Transplant Lymphopenia is Associated with Higher Risk of Graft Failure, Death and Viral Infections

    A. Dujardin1, M. Lorent2, C. Kerleau1, S. Brouard3, M. Giral1

    1Nephrology, Nantes University Hospital, Nantes, France, 2UMR_S 1246, INSERM, Nantes, France, 3CRTI  UMR 1064, Inserm, Nantes, France

    *Purpose: The transplantation field needs biomarkers to assess the level of immunosuppression. In this study, we aimed to analyze the independent correlation between the number…
  • 2019 American Transplant Congress

    Use of Anti-Vimentin Antibodies as a Possible Marker for Graft Dysfunction Following Renal Transplant, a Prospective Study

    E. Acosta1, T. Divanyan1, D. Patel1, F. Jourd'heuil2, D. Jourd'heuil2, R. Lopez-Soler3

    1Albany Medical College, Albany, NY, 2Molecular and Cellular Physiology, Albany Medical College, Albany, NY, 3Surgery, Section of Transplantation, Albany Medical College, Albany, NY

    *Purpose: In our previously published work, we showed that presence of anti-vimentin antibodies (AVA) after renal transplant correlated with early IFTA (Interstitial Fibrosis and Tubular…
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