2019 American Transplant Congress
Trends in Vascularized Composite Allograft Transplantation in the United States
*Purpose: Characterize patterns in VCA transplantation in the U.S.*Methods: Analyses include all VCA recipients in the U.S through October 2018 and all VCA candidates between…2019 American Transplant Congress
Clinical Response to Pathological Finding in Uterus Transplantation
Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX
*Purpose: Uterus transplantation has recently proven to be the first successful treatment for absolute uterine factor infertility with demonstration of live births. All reported episodes…2019 American Transplant Congress
Heart-Associated Cytokine and Endothelial Patterns Dominate the Ischemia/Reperfusion Response in Recipients of Combined Heart/Lung Transplantation in Comparison to Lung Transplantation
*Purpose: Organ-specific differences are discussed for ischemia/reperfusion injury (IRI) in cardiothoracic transplantation (Tx) but rarely compared directly in a clinical setting. Therefore, we compared a…2019 American Transplant Congress
Determining the Molecular Nature and Role of Cytoglobin in Chronic Allograft Nephropathy
*Purpose: Although it is usually accepted that the kidney is prone to hypoxic injury, the importance of hypoxia in chronic kidney disease (CKD) as well…2019 American Transplant Congress
Assessment of Culture/Preservation Conditions on Survival and Function of Islets
Surgery, Virginia Commonwealth University, Richmond, VA
*Purpose: Culture or preservation of human islets prior to transplantation has been adopted by various centers because it may reduce immunogenicity, suppress exocrine contamination and…2019 American Transplant Congress
B Cell Derived Exosomes Are Associated with Antibody Mediated Rejection in Kidney Transplant Recipients Desensitized for a Positive Cross-Match
*Purpose: Kidney transplant recipients undergoing desensitization for a positive cross-match are at very high risk of developing Antibody-Mediated Rejection (AMR). Because of desensitization, peripheral circulating…2019 American Transplant Congress
Surveillance Biopsy Utilization Reported Higher In Transplant Centers Performing Over 100 Kidney Transplants Per Year.
*Purpose: To assess the frequency of surveillance biopsies in kidney transplant patients in transplant centers performing greater than 100 transplants per year, and to compare…2019 American Transplant Congress
Symptom Burden after Living Donor Kidney Transplant Measured with the Functional Assessment of Cancer Therapy – Kidney Symptom Index is Associated with Worse Transplant Outcomes
Northwestern University, Chicago, IL
*Purpose: As the FDA and other stakeholders in transplantation look for fit-for-purpose (FFP) patient-reported outcome measures, there is a need to better understand symptom burden…2019 American Transplant Congress
Donor-Derived Cell-Free DNA is Associated Specifically with Antibody Mediated Injury in Patients with Renal Allograft Dysfunction
1Fundeni Clinical Institute, Bucharest, Romania, 2University of Washington, Seattle, WA
*Purpose: Donor-derived cell-free DNA (dd-cfDNA) has been proposed as a noninvasive biomarker to differentiate rejection from other types of injury in renal allografts.*Methods: We analyzed…2019 American Transplant Congress
The Impact of Calcineurin Inhibitors on De Novo DSA in Primary Kidney Transplantation
Nagoya Daini Red Cross Hospital, Nagoya Aichi, Japan
*Purpose: De novo DSA was demonstrated as a cause of chronic AMR, leading to worse graft survival. New strategies to treat chronic AMR have been…
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