Am J Transplant, Volume 19, Suppl 3 Archives - Page 194 of 214 - ATC Abstracts

2019 American Transplant Congress
A Naturalistic Study of De Novo Extended-Release Tacrolimus Tablets vs. Tacrolimus Immediate-Release Capsules in Kidney Transplant Recipients
T. A. Horwedel¹, C. E. Carthon¹, S. E. January¹, A. Gharabagi¹, R. Delos Santos², J. C. Hagopian¹
¹Pharmacy, Barnes-Jewish Hospital, Saint Louis, MO, ²Nephrology, Washington University School of Medicine, Saint Louis, MO
*Purpose: Beginning in December 2015, our center instituted a protocol change moving to de novo use of LCPT. The objective of this study is to…
2019 American Transplant Congress
Optimizing Opportunity and Benefits of Steroid Avoidance in the New KAS Era
S. Sultan, M. Aull, R. Friedlander, V. K. Sharma, D. Serur, A. Watkins, S. Kapur, D. Dadhania
New York Presbyterian / Weill Cornell, New York, NY
*Purpose: The introduction of the new Kidney Allocation System (KAS) in 2014 has facilitated transplantation of sensitized patients with high CPRA. However, the CPRA value…
2019 American Transplant Congress
Staged Procedure In Simultaneous Liver And Kidney Transplant -the “Swedish” Experience
A. Gravetz
Transplant Surgery, Swedish Medical Center, Seattle, WA
*Purpose: As many as 30% of liver transplant candidates have renal insufficiency requiring a combined liver and kidney transplantation. The prolonged and complex simultaneous liver-kidney…
2019 American Transplant Congress
Statin Underutilization in Patients Listed for Liver Transplant
K. Mishra¹, S. Naffouj¹, S. Modi¹, C. Dagher¹, S. Gorgis¹, D. Venkat²
¹Internal Medicine, Henry Ford Hospital, Detroit, MI, ²Transplant Hepatology, Henry Ford Hospital, Detroit, MI
*Purpose: Current guidelines recommend statin use in high risk patients based on the ASCVD (atherosclerotic cardiovascular disease) score, diabetes, or LDL levels. Despite several trials…
2019 American Transplant Congress
Letermovir for CMV Treatment in Solid Organ Transplant
O. Witkowsky, M. Chunduru, A. Chung, A. Diez
The Ohio State University Wexner Medical Center, Columbus, OH
*Purpose: Letermovir (LET), a novel anti-CMV agent, was recently approved for CMV prophylaxis in stem cell transplant recipients and is currently under investigation as a…
2019 American Transplant Congress
Target Itraconazole Trough Concentration for Prophylaxis in Lung Transplant
J. A. Morillas-Rodriguez¹, H. Hassouna², F. Marco-Canosa³, K. D. Brizendine¹
¹Infectious disease, Cleveland Clinic, Cleveland, OH, ²Infectious disease, Spectrum health, Grand rapids, MI, ³Cleveland Clinic, Cleveland, OH
*Purpose: Itraconazole (ITR) therapeutic drug monitoring (TDM) for prophylaxis in lung transplant recipients (LTR) is not well characterized. Our purpose was to evaluate ITR trough…
2019 American Transplant Congress
A Nurse-Driven Influenza Vaccine Ordering Protocol Improves Vaccination Rates in Abdominal Organ Transplant Recipients
T. Ho¹, C. D. Sifri², J. D. Lewis³
¹Department of Medicine, Virginia Commonwealth University, Richmond, VA, ²Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, ³Division of Infectious Diseases, Medical University of South Carolina, Charleston, SC
*Purpose: Solid organ transplant (SOT) recipients are at increased risk of influenza infection and severe influenza-related complications. The influenza vaccine is a safe and effective…
2019 American Transplant Congress
Combined Ischemic and Rapamycin Preconditioning Alleviated Liver Ischemia and Reperfusion Injury by Restoring Autophagy in Old Mice
Z. Rao, X. Pan, W. Zhong, Z. Ding, H. Zhou, C. Liu
The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
*Purpose: Old livers are more damaged by hepatic ischemia and reperfusion (IR) injury than young livers. The aim of this study was to investigate the…
2019 American Transplant Congress
Pgc1α Protects against Graft Ischemic Injury and Reduces Alloimmunity
T. J. Borges¹, M. T. Tran², S. Cai¹, N. Murakami¹, A. Uffing¹, M. Uehara¹, E. P. Rhee³, S. M. Parikh⁴, L. V. Riella¹
¹Schuster Transplantation Research Center, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, ²Division of Nephrology and Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, ³Nephrology Division, Massachusetts General Hospital, Boston, MA, ⁴Division of Nephrology and Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
*Purpose: Prolonged ischemia reperfusion injury (IRI) during organ transplantation activates innate immunity and potentiates adaptive immunity, leading to worse transplant outcomes. The mitochondria are particularly…
2019 American Transplant Congress
Donor Management in Donation after Brain Death: A Window of Opportunity – Are Pro-Inflammatory Mediators the Target and What is the Effect of Duration of Brain Death?
K. D. Bera¹, J. Tabak², M. L. Lo Faro¹, R. J. Ploeg¹
¹Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom, ²University of Exeter, Exeter, United Kingdom
*Purpose: Donation after brain death (BD) is a crucial source of transplanted organs - uncertainty remains how duration of BD contributes to outcomes: This study…