Am J Transplant, Volume 19, Suppl 3 Archives - Page 190 of 214 - ATC Abstracts

2019 American Transplant Congress
Upregulation of Endothelial HLA Class II as a Marker of Antibody Mediated Rejection in Heart Allograft Biopsies
Q. Cai, Y. Butt, A. Hendricks, J. Torrealba
Pathology, UTSW Medical Ctr, Dallas, TX
*Purpose: In 2013, the ISHLT (International Society of Heart and Lung Transplant) introduced the working classification for pathological changes associated with antibody-mediated rejection of the…
2019 American Transplant Congress
What’s in a High Dose? An Analysis of Tacrolimus Pharmacokinetic Parameters in Rapid Metabolizers
P. West-Thielke¹, A. Maldonado², S. J. Patel³, D. R. Stevens³, U. Meier-Kriesche³, D. Brennan⁴
¹University of Illinois, Chicago, Chicago, IL, ²Vidant Medical Center, Greenville, NC, ³Veloxis Pharmaceuticals Inc., Cary, NC, ⁴Johns Hopkins University School of Medicine, Baltimore, MD
*Purpose: CYP3A5*1 expressers exhibit differences in immediate-release tacrolimus (IR-Tac) PK and require higher doses of IR-Tac to maintain therapeutic trough concentrations. LCP-Tacrolimus (LCPT) demonstrates a…
2019 American Transplant Congress
Recipient Outcomes Following Transplantation Of Allografts From Older Live Kidney Donors With Hypertension
F. Al Ammary¹, S. Yu², A. D. Muzaale³, D. C. Brennan⁴, A. C. Wiseman⁵, D. L. Segev³, A. B. Massie³
¹Johns Hopkins Medicine, Greenbelt, MD, ²Johns Hopkins Medicine, Baltimore, MD, ³Surgery, Johns Hopkins Medicine, Baltimore, MD, ⁴Medicine, Johns Hopkins Medicine, Baltimore, MD, ⁵Medicine, University of Colorado, Aurora, CO
*Purpose: Healthy older live kidney donor candidates with hypertension may provide an opportunity to increase live kidney donation. However, the impact of this practice on…
2019 American Transplant Congress
Ready for Prime Time: Intentional Allocation of Hepatitis C Positive Livers into Hepatitis C Negative Recipients
P. N. Martins¹, B. Movahedi¹, D. Devuni², P. Mahboub¹, A. Bozorgzadeh¹
¹Surgery, Division of Transplantation, University of Massachusets, Worcester, MA, ²Medicine, Division of Hepatology, University of Massachusets, Worcester, MA
*Purpose: The current discrepancy between supply and demand of liver grafts has dramatically increased the waiting time and mortality on the waiting list. The recent…
2019 American Transplant Congress
Erythropoietin Ameliorates Parent to F1 Murine Graft versus Host Disease by Inhibiting T_FH
A. Angeletti¹, C. Donadei¹, A. Cumpelik¹, C. Cantarelli¹, C. Guglielmo¹, G. La Manna², P. Heeger¹, P. Cravedi¹
¹Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, ²Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale (DIMES), Policlinico Sant'Orsola-Malpighi, Bologna, Italy
*Purpose: Building upon our previously generated evidence that erythropoietin (EPO) directly inhibits effector T cells (JASN 2015, 2017) and reduces autoantibody formation in murine lupus,…
2019 American Transplant Congress
Evaluation of Influenza Virus Antibody Response in Naturally Infected and Vaccinated Transplant Recipients by Protein Microarray
C. Hirzel, A. Chruscinski, V. H. Ferreira, A. G. L'Huillier, A. Humar, D. Kumar
University Health Network, Toronto, ON, Canada
*Purpose: Influenza A virus (IAV) infection is known to be an important cause of morbidity in solid organ transplant (SOT) recipients. The objective of our…
2019 American Transplant Congress
Lung Transplant Outcomes after CABG
S. Huddleston¹, R. Aggarwal¹, S. Jackson², N. Lemke¹
¹Surgery, University of Minnesota, Minneapolis, MN, ²Surgery, Fairview Health Services, Minneapolis, MN
*Purpose: Prior coronary artery bypass grafting (CABG) has been a contraindication to lung transplantation (LTx) due to increased mortality associated with bilateral lung transplant. We…
2019 American Transplant Congress
C4d Positivity in Renal Biopsies Following A₂ to B Kidney Transplantation: Not All A B O Incompatibilities Are Equal
S. Radomski¹, G. Vranic², B. Thomas², P. Abrams², M. Cooper², A. Gilbert²
¹Georgetown University School of Medicine, Washington, DC, ²Medstar Georgetown Transplant Institute, Washington, DC
*Purpose: With the new allocation rules implemented in 2014, the number of transplants from A2 and A2B donors to B or O recipients (minor ABO…
2019 American Transplant Congress
Increase in Deceased Donor Acceptance Rate After Implementing Uniform Acceptance Criteria
C. Klein, T. Ommert, J. Hundley, J. Lizcano, A. Ray, R. Cross, K. Payne
Piedmont Transplant Institute, Atlanta, GA
*Purpose: Over 100,000 candidates are listed for kidney transplant in the United States, yet less than 20,000 patients are transplanted annually. In 2013, over 2,500…
2019 American Transplant Congress
Predictors of Multidrug-Resistant Organisms among Solid Organ Transplant Donors
J. A. Anesi¹, E. A. Blumberg¹, J. H. Han¹, D. H. Lee², H. Clauss³, A. Climaco⁴, R. Hasz⁵, E. Molnar³, D. Alimenti¹, S. West⁵, W. Bilker¹, P. Tolomeo¹, E. Lautenbach¹
¹University of Pennsylvania, Philadelphia, PA, ²Drexel University College of Medicine, Philadelphia, PA, ³Temple University, Philadelphia, PA, ⁴Albert Einstein Medical Center, Philadelphia, PA, ⁵Gift of Life Donor Program, Philadelphia, PA
*Purpose: Transplant guidelines recommend exercising caution when considering donor organs that may be infected or colonized with multidrug-resistant organisms (MDROs). Approaches to identifying such potentially…