Am J Transplant, Volume 19, Suppl 3 Archives - Page 189 of 214 - ATC Abstracts

2019 American Transplant Congress
Evaluation of Medication Burden in Kidney Transplant Recipients at Time of Index Hospitalization
J. Hardcopf¹, H. Meadows¹, T. Harrison¹, H. Corbo¹, B. O'brien¹, J. N. Fleming¹, C. Perez¹, N. Patel¹, N. Pilch¹, P. K. Baliga², D. DuBay², D. Taber¹
¹Department of Pharmacy Services, Medical University of South Carolina, Charleston, SC, ²Division of Transplant Surgery, Department of Surgery, Medical University of South Carolina, Charleston, SC
*Purpose: This study will assess whether a higher number of medication changes from pre- to post-transplant lead to worse clinical outcomes and higher healthcare utilization…
2019 American Transplant Congress
Targeted Proteomic Analysis Detects Acute T Cell-Mediated Kidney Allograft Rejection in Belatacept-Treated Patients
M. van der Zwan, D. A. Hesselink, M. C. Clahsen-van Groningen, C. C. Baan
Erasmus MC, Rotterdam, Netherlands
*Purpose: There is an unmet need for reliable minimally-invasive diagnostic biomarkers for immunological allograft monitoring and detection of acute kidney transplant rejection. Here, targeted proteomic…
2019 American Transplant Congress
Utilizing Ides To Eliminate Residual Antibodies Targeting Xenografts
C. Rickert, K. Lee, N. Tanimine, J. Lei, A. Cuenca, N. Feeney, K. Deng, H. Yeh, J. F. Markmann
Massachusetts General Hospital, Boston, MA
*Purpose: A significant hinderance to the successful use of xenotransplantation has been the presence of preformed antibodies against the donor antigens, known as xenoantigens. Using…
2019 American Transplant Congress
Comparison of Minimal Incision Kidney Transplantation with Conventional Incision Kidney Transplantation: Interim Report of a Randomized Controlled Trial
T. Lin, T. Song, Y. Jiang, Y. Fan, X. Wang, Z. Huang, J. Liu, Z. Wang
Organ Transplantation Center, Urology Department, Urology Research Institute, WestChina Hospital, Sichuan University, Chengdu, China
*Purpose: Minimally invasive surgery is rarely applied in kidney transplantation. Few studies have mentioned small incision kidney transplantation, while the incision length is still about…
2019 American Transplant Congress
Expansion of Regulatory T and B Cells in Swine Rendered Tolerant of Allogeneic Vascularized Composite Allografts via Mixed Chimerism
G. Saviane¹, A. Lellouch¹, A. Andrews¹, L. Lantieri², M. Randolph¹, G. Benichou¹, C. Cetrulo Jr¹
¹Center for Transplantation Sciences, Division of Plastic Surgery, Boston, MA, USA, Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA, Boston, MA, ²European Georges Pompidou Hospital, University of Paris, Department of Plastic Surgery, Paris, France
*Purpose: Prevention of acute rejection of vascularized composite allografts (VCAs) requires ongoing systemic immunosuppression, which subject patients to infectious, metabolic, reno-vascular and neoplastic complications. It…
2019 American Transplant Congress
6-Minute Walk Testing in Patients on the Kidney Transplant Waitlist
X. S. Cheng¹, J. Lee², K. V. Discipulo¹, J. Myers³, J. C. Tan¹
¹Nephrology, Stanford University, Palo Alto, CA, ²Kidney Transplant, Stanford Hospital, Palo Alto, CA, ³Cardiology, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA
*Purpose: Poor physical function in kidney transplant candidates is associated with frailty, sub-optimal transplant outcomes, and higher health care utilization. We need an instrument to…
2019 American Transplant Congress
Digital Imaging Software vs. the “Eyeball” Method in Quantifying Steatosis in a Liver Biopsy
J. Long¹, J. Motter¹, S. Besharati¹, S. Jerman², R. Anders¹, A. Ortiz², D. Bowman², T. Dunn³, D. Lee⁴, A. Massie¹, R. Barth⁵, B. Philosophe¹
¹Johns Hopkins, Baltimore, MD, ²Indica Labs, Corrales, NM, ³UPenn, Philadelphia, PA, ⁴Mayo Clinic, Jacksonville, FL, ⁵University of MD, Baltimore, MD
*Purpose: The use of steatotic livers is controversial, but may represent an underutilized resource to increase the donor pool. Although
2019 American Transplant Congress
Wide Geographic Variability in the Proportion of Donors with Cardiac Death – Lost Opportunities for Organ Donation?
E. M. Sonnenberg¹, D. S. Goldberg², J. Y. Hsu³, P. P. Reese², P. L. Abt¹
¹Department of Surgery, University of Pennsylvania, Philadelphia, PA, ²Department of Medicine, University of Pennsylvania, Philadelphia, PA, ³Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA
*Purpose: Donation after cardiac death (DCD) donors are largely not considered by organ procurement organization (OPO) metrics, as DCD donors are only counted in donor…
2019 American Transplant Congress
Role of NF-kB in Release of Isletokines via Exosomes in Response to Islet Stress
P. Saravanan¹, M. Kanak¹, J. Kalivarathan¹, M. Lawrence², M. Levy¹, B. Naziruddin³
¹Department of Surgery, Virginia Commonwealth University, VCU Health, Richmond, VA, ²Islet Cell Lab, Baylor Scott and White Research Institute, Dallas, TX, ³Simmons Transplant Institute, Baylor Scott and White Medical Center, Dallas, TX
*Purpose: Human islets are exposed to a range of inflammatory stimuli upon transplantation that leads to poor graft survival. Identifying the various signaling events may…
2019 American Transplant Congress
Success in Lung Transplantation Outcomes after Receiving a Standardized Desensitization Therapy
S. Ganesh¹, C. L. Prohaska², C. Mares², M. J. Everly³
¹Medicine, Keck Medical Center at the University of Southern California, Los Angeles, CA, ²BioMatrix, Weston, FL, ³Terasaki Research Institute, Los Angeles, CA
*Purpose: With a goal to develop a safe, effective, and consistent approach to desensitization therapy using IVIg in lung transplant (LuT), we instituted a standard…