Am J Transplant, Volume 19, Suppl 3 Archives - Page 188 of 214 - ATC Abstracts

2019 American Transplant Congress
Anti CD45RB Antibody Therapy Attenuates Renal Ischemia Reperfusion Injury by Inducing Regulatory B Cells
S. Lee¹, S. Park¹, J. Hwang¹, J. Ryu², T. Koo², C. Ahn², J. Yang³
¹Biomedical Research Institute, Transplantation Center, Seoul National University Hospital, Seoul, Korea, Republic of, ²Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Republic of, ³Department of surgery, Seoul National University Hospital, Seoul, Korea, Republic of
*Purpose: Regulatory B cells (Bregs) are a new B cell subset that suppresses immune responses. Recently, both anti-CD45RB and anti-Tim-1 treatments have been found to…
2019 American Transplant Congress
Improved Transplant Outcomes in Ischemia-Free Liver Transplantation: A Report of the First 30 Cases
X. He, Z. Guo, W. Ju, Q. Zhao, S. Huang, J. Yang, L. Wang, Y. Tang, Z. Zhang, Z. Zhu, L. Yang, Y. Zhu, F. Gong, C. Cai, W. Huang, G. Chen, M. Chen, F. Ji, M. Han, A. Hu, L. Wu, Y. Ma, D. Wang, J. Huang, X. Li
Organ Transplant Center, the First Affiliated Hospital of SYSU, Guangzhou, China
*Purpose: We developed a novel procedure called ischemia-free liver transplantation (IFLT) to bridge liver grafts from donors to recipients without cessation of blood supply. Herein,…
2019 American Transplant Congress
De Novo Donor Specific Antibody and Panel Reactivity Antibody Are Critical Risk Factors for Antibody Mediated Rejection of Kidney Allograft after Simultaneous Liver-Kidney Transplantation (a Single Center Study Using Surveillance Renal Biopsies)
Y. Sun¹, A. Zhang², Z. Zaky²
¹Avalon Medical University, Willemstad, Netherlands Antilles, ²Cleveland Clinic, Cleveland, OH
*Purpose: Even though the liver may provide immunologic protection to the kidney from hyperacute rejection, previous publications suggest this protective effect is not sufficient to…
2019 American Transplant Congress
Apolipoprotein L1 Genotyping in Potential African American Living Kidney Donors
P. Gudsoorkar, M. Anand, T. Kaur, S. Shah, S. Bumb, A. Govil, B. G. Abu Jawdeh
U.Cincinnati, Cincinnati, OH
*Purpose: African Americans(AA) account for 13% of the US population, yet compose more than one third of dialysis patients. Inheriting two Apolipoprotein L1 gene (APOL1)…
2019 American Transplant Congress
Adjuvant Immunotherapeutic Approach For Liver Transplant Recipients With Hepatocellular Carcinoma Using Donor Liver Derived Natural Killer Cells
M. Ohira¹, R. Hotta¹, Y. Imaoka¹, K. Sato¹, Y. Tanaka¹, A. G. Tzakis², S. Nishida³, H. Ohdan¹
¹Hiroshima University, Hiroshima, Japan, ²Cleveland Clinic Florida, Weston, FL, ³New York Medical College, Valhalla, NY
*Purpose: Although liver transplantation (LT) is a preferred treatment for selected patients with Hepatocellular carcinoma (HCC), HCC-recurrence would be a still important medical problem. Most…
2019 American Transplant Congress
Solving Target Recognition and Activation Mediated by Non-HLA Agonistic Antibodies Targeting ETAR
A. Philippe¹, R. Catar¹, P. Scheerer², M. Szczepek², D. Dragun¹
¹Nephrology and Medical Intensive Care, Charité Universitätsmedizin Berlin, Berlin, Germany, ²Institute of Medical Physics and Biophysics, Charité Universitätsmedizin Berlin, Berlin, Germany
*Purpose: Endothelin-1 type A receptor (ETAR) exhibits multiligand binding abilities and may signal upon natural ligand Endothelin-1 (ET-1) and non-HLA ETAR-agonistic IgG (ETAR-IgG)-mediated stimulation similar…
2019 American Transplant Congress
A Single-Center Experience with a 6-Month Regimen of Pneumocystis jiroveci Pneumonia Prophylaxis in HIV-Positive Kidney Transplant Recipients
C. Mejia¹, G. Malat², D. H. Lee³, S. Epstein¹, M. Harhay³, L. Levin Mizrahi³, K. Ranganna³
¹Drexel University, Philadelphia, PA, ²Hahnemann University Hospital, Philadelphia, PA, ³Medicine, Drexel University, Philadelphia, PA
*Purpose: Pneumocystis jiroveci pneumonia (PJP) prophylaxis is recommended for all kidney transplant recipients (KTR) for after transplant. HIV-positive KTRs represent a unique subset, and there…
2019 American Transplant Congress
The Impact of Removing DSA as a First Unit of Lung Allocation: Preliminary Results
R. R. Lehman¹, K. Uccellini², M. Skeans³, M. Valapour³, E. D. Lease⁴, R. Daly⁵, K. M. Chan⁶
¹Research, United Network for Organ Sharing, Richmond, VA, ²Policy, United Network for Organ Sharing, Richmond, VA, ³SRTR, Minneapolis, MN, ⁴Univ of Washington, Seattle, WA, ⁵Mayo Clinic, Rochester, MN, ⁶Univ of Michigan, Ann Arbor, MI
*Purpose: In an emergency action on November 24, 2017 the Organ Procurement and Transplantation Network (OPTN) altered US lung allocation policy by replacing the donor…
2019 American Transplant Congress
Circulating Mirnas Regulate Gene Expression In Kidney Tissue During Transplant Glomerulopathy
C. Kuscu¹, V. Sai Bontha¹, C. Kuscu¹, D. Maluf¹, A. Bajwa¹, J. Eason¹, V. Mas¹, E. Akalin²
¹UTHSC, Memphis, TN, ²Albert Einstein College of Medicine, NYC, NY
*Purpose: Post-transplant glomerular disease includes membranous glomerulopathy (MG), secondary or primary focal segmental glomerulosclerosis (FSGS). Furthermore, at post transplant, TG is an important cause of…
2019 American Transplant Congress
Predictors and Outcomes of Acute Graft-versus-Host Disease after Liver Transplant
A. Caines¹, S. Nagai², R. Salgia¹
¹Gastroenterology and Hepatology, Henry Ford Health System, Detroit, MI, ²Transplant Surgery, Henry Ford Health System, Detroit, MI
*Purpose: Graft-versus-Host Disease (GVHD) is a rare complication of liver transplant (LT) that has an estimated incidence of 0.1%-2% per year and is associated with…