Am J Transplant, Volume 19, Suppl 3 Archives - Page 188 of 214 - ATC Abstracts

2019 American Transplant Congress
Use of Low Dose Interleukin-2 to Expand Regulatory T-cells and Facilitate the Complete Discontinuation of Immunosuppression in Human Liver Transplantation
T. Lim¹, P. Ruiz², A. Kurt², E. Kodela², M. Martinez-Llordella², T. Tree³, A. Sanchez-Fueyo¹
¹Institute of Liver Studies, King's College Hospital, London, United Kingdom, ²Department of Liver Sciences, King's College London, London, United Kingdom, ³Department of Immunobiology, King's College London, London, United Kingdom
*Purpose: Low dose interleukin-2 (LDIL-2) is capable of expanding endogenous CD4+CD25+FoxP3+ regulatory T-cells (Tregs) in vivo but its role in human solid organ transplantation is…
2019 American Transplant Congress
Brief Normothermic Machine Perfusion is Superior to Cold Storage Alone – A Paired Discarded Human Kidney Analysis
A. Hameed¹, E. Patrick², D. B. Lu¹, C. P'ng¹, M. Hu², Y. Chew², R. De Roo¹, L. Yuen¹, W. Hawthorne¹, N. Rogers¹, H. Pleass¹
¹Westmead Hospital, Sydney, Australia, ²Westmead Institute for Medical Research, Sydney, Australia
*Purpose: The use of marginal has increased due to ongoing donor shortages. These kidneys have higher rates of graft discard after procurement, and also have…
2019 American Transplant Congress
Efficacy and Safety with Empagliflozin in Renal Transplant Recipients with Post-Transplant Diabetes Mellitus
K. E. Kvitne¹, T. S. Halden², A. Åsberg², K. Midtvedt², A. Hartmann², T. Jenssen²
¹Department of Pharmaceutical Biosciences, School of Pharmacy, University of Oslo, Oslo, Norway, ²Department of Transplantation Medicine, Section of Nephrology, Oslo University Hospital, Rikshospitalet, Oslo, Norway
*Purpose: Post-transplant diabetes mellitus (PTDM) is a highly prevalent condition following renal transplantation, associated with increased risk of cardiovascular disease and impaired patient survival. Sodium-glucose…
2019 American Transplant Congress
Undernutrition is Associated with Impaired T Cell Protective Immunity in Pediatric Kidney Transplantation
E. T. Chambers¹, C. Chan¹, R. Ettenger², P. Grimm³, E. Reed², M. Sarwal⁴, L. Stempora⁵, B. Warshaw⁶, C. Zhao¹, O. Martinez⁷, A. Kirk⁵
¹Pediatrics, Duke University, Durham, NC, ²Pediatrics, UCLA, Los Angeles, CA, ³Pediatrics, Stanford, Palo Alto, CA, ⁴Pediatrics, UCSF, San Francisco, CA, ⁵Surgery, Duke University, Durham, NC, ⁶Pediatrics, Emory University, Atlanta, GA, ⁷Surgery, Stanford, Palo Alto, CA
*Purpose: Undernutrition has been associated with T cell immune cell dysfunction and infectious complications in non-immunosuppressed children. Thus, we aimed to define T cell phenotypes…
2019 American Transplant Congress
Predicting HCC Recurrence Following Liver Transplant – A Machine Learning Approach
L. F. Lau¹, W. Nelson², A. Gorgen¹, L. Erdman², P. Abreu¹, A. Goldenberg², G. Sapisochin¹
¹Department of Surgery, University of Toronto, Toronto, ON, Canada, ²The Center for Computational Medicine, The Hospital for Sick Children, Toronto, ON, Canada
*Purpose: The liver transplant listing criteria for hepatocellular carcinoma (HCC) is controversial. Policies aim to prevent tumor recurrence but it has been difficult to encompass…
2019 American Transplant Congress
Can Imputation of HLA Allele Level Typing Be Used Clinically in a Multiethnic Population?
R. M. Engen¹, A. M. Jedraszko¹, A. Tambur²
¹Ann & Robert H Lurie Children's Hospital of Chicago, Chicago, IL, ²Northwestern University, Chicago, IL
*Purpose: Assignment of eplets in transplantation for the purpose of matching or risk stratification requires high-resolution HLA typing, which is not readily available. Computer algorithms…
2019 American Transplant Congress
African American Living Kidney Donors’ Perceptions of APOL1 Genetic Testing and Its Impact on Ethnic Identity
E. J. Gordon¹, D. Amortegui¹, C. Wicklund¹, J. Friedewald¹, R. Sharp²
¹Northwestern University, Chicago, IL, ²Mayo Clinic, Rochester, MN
*Purpose: Apolipoprotein L1 (APOL1) risk variants may contribute to live kidney donors’ (“donors”) kidney failure post-donation. Because professional guidelines suggest informing potential donors with African…
2019 American Transplant Congress
Donor Insulin Therapy Predicts Better Graft Survival in Pancreas Transplantation
I. Shapey, A. Summers, H. Khambalia, C. Fullwood, N. Hanley, T. Augustine, M. Rutter, D. van Dellen
University of Manchester, Manchester, United Kingdom
*Purpose: Organ donors frequently develop hyperglycaemia in intensive care, which is managed with insulin. In islet and solid pancreas transplantation (PT) we reported that Donor…
2019 American Transplant Congress
The Immigrant Bonus: Non US Deceased Donor Kidney Transplant Recipients Have Superior Outcomes versus US Citizen Recipients. A Retrospective Study of 30,092 Subjects Using the Organ Procurement and Transplant Network (OPTN) from 1992-2015
T. Butler¹, A. Rana², S. Fink¹
¹Transplant Surgery, Crozer Prospect Medical Center-Drexel University, Upland, PA, ²Transplant Surgery, Baylor College of Medicine, Houston, TX
*Purpose: In 2017, there were 19,849 kidney transplant recipients, and most of these patients were US Citizens1. There has been however, a significant amount non-US…
2019 American Transplant Congress
Proximal Splenic Artery Embolization For Refractory Ascites And Hydrothorax After Liver Transplant: A Single Center Analysis Of Factors Associated With Success
L. Lomaglio, G. D'Amico, S. Armanyous, T. Diago Uso, K. Hashimoto, B. Eghtesad, M. Fujiki, F. Aucejo, K. Sasaki, C. Kwon, C. Coppa, M. Bayona Molano, C. Lindenmeyer, C. Miller, C. Quintini
Cleveland Clinic, Cleveland, OH
*Purpose: The aims of this study were to (1) assess the efficacy of proximal SAE for the treatment of RA and RH caused by portal…