Am J Transplant, Volume 19, Suppl 3 Archives - Page 185 of 214 - ATC Abstracts

2019 American Transplant Congress
Assessment of Serum Tim3 and Gal9 Levels in Predicting the Risk of Infection after Kidney Transplantation
Y. Shi¹, y. li², Y. Li², L. Yan², J. Tang², X. Wu², Y. Bai², Y. An², B. Dai², C. Yang², L. Wang²
¹Department of Nephrology, West China Hospital, Chengdu, China, ²Department of Laboratory Medicine, West China Hospital, Chengdu, China
*Purpose: Infection remains a major cause of morbidity and mortality after kidney transplantation (KT). However, reliable biomarkers to predict the occurrence of post-transplant infection are…
2019 American Transplant Congress
Kidney Xenotransplantation from Genetically Engineered Pigs to Baboons with FDA-Approved Immunosuppressive Therapy
T. Yamamoto¹, H. Hara¹, J. Foote¹, E. C. Klein², H. J. Schuurman³, L. Wang¹, Q. Li¹, H. Zhou¹, J. Li¹, J. A. Tector¹, Z. Zhang², M. Ezzelarab², R. Lovingood¹, D. Ayares⁴, D. E. Eckhoff¹, D. K. Cooper¹, H. Iwase¹
¹University of Alabama at Birmingham, Birmingham, AL, ²University of Pittsburgh, Pittsburgh, PA, ³Schubiomed Consultancy, Utrecht, Netherlands, ⁴Revivicor, Blacksburg, VA
*Purpose: Genetically-engineered pigs might present a solution to the critical shortage of organs for clinical transplantation. The aims of this study were to evaluate the…
2019 American Transplant Congress
External Validation of the DCD-N Score and a Linear Prediction Model to Identify Potential Candidates for Donation after Circulatory Death: A Nation-Wide Cohort Study
M. F. Nijhoff¹, R. A. Pol¹, M. Volbeda¹, A. M. Kotsopoulos², J. P. Sonneveld³, J. van Dongen⁴, W. F. Abdo⁵, V. Silderhuis⁶, C. Moers¹
¹Surgery – Organ Donation and Transplantation, University Medical Center Groningen, Groningen, Netherlands, ²Department of Intensive Care Unit (ICU), Elisabeth Twee Steden Hospital, Tilburg, Netherlands, ³Department of ICU, Isala, Zwolle, Netherlands, ⁴Department of ICU, Catharina hospital, Eindhoven, Netherlands, ⁵Department of ICU, Radboud University Medical Center, Nijmegen, Netherlands, ⁶Department of ICU, Medisch Spectrum Twente, Enschede, Netherlands
*Purpose: Donation after circulatory death (DCD) is most often a controlled procedure after planned withdrawal of life-sustaining treatment (WLST) at an intensive care unit. In…
2019 American Transplant Congress
Renal Failure as a Complication of Vascularized Composite Allotransplantation
R. N. Barth¹, J. T. Shores², G. Brandacher², M. H. Levine³, A. Weissenbacher⁴, A. J. Nam¹, N. Shockcor¹, E. D. Rodriguez⁵, S. Schneeberger⁴, W. Lee², S. T. Bartlett¹, L. Levin³
¹University of Maryland School of Medicine, Baltimore, MD, ²Johns Hopkins University School of Medicine, Baltimore, MD, ³University of Pennsylvania School of Medicine, Philadelphia, PA, ⁴Medical University Innsbruck, Innsbruck, Austria, ⁵New York University School of Medicine, New York, NY
*Purpose: Vascularized composite allotransplantation (VCA) has demonstrated impressive outcomes in areas of extremity (UETx), face (FTx), genitourinary, and abdominal wall transplantation with up to twenty…
2019 American Transplant Congress
Long Term Outcomes Using Tocilizumab For The Treatment Of Chronic Antibody Mediated Rejection
J. Choi¹, E. Huang¹, O. Aubert², A. Vo¹, A. Peng¹, R. Najjar¹, S. Sethi¹, N. Ammerman¹, K. Lim¹, D. Puliyanda¹, A. Loupy², S. Jordan¹
¹Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA, ²Paris Translational Center for Organ Transplantation, Paris, France
*Purpose: Limited options exist for the treatment of kidney allograft rejection and preservation of allograft function. We reported our experience with anti-IL-6R (tocilizumab, TCZ) as…
2019 American Transplant Congress
Reduction in Waitlist Time Using HCV Positive Liver Grafts in HCV Negative Recipients
E. M. Bugeaud, N. Bzowej, J. Hand, J. Scheuermann, H. Bohorquez, C. Brown, D. Bruce, I. Carmody, A. Cohen, S. Joshi, N. Latt, J. Seal, D. Sonnier, G. Therapondos, G. Tyson, N. Girgrah, G. Loss
Ochsner Health System, New Orleans, LA
*Purpose: With direct-acting antiviral (DAA) therapy, we feel that HCV+ organs are safe for all patients regardless of their HCV status and have adopted a…
2019 American Transplant Congress
Changes in the Fate of KDPI < 35% Kidneys before and after Implementation of the New Kidney Allocation System
K. Eng, E. Grodstein, L. Castellanos Reyes, L. Teperman, C. Sethna, P. Singer
Northwell Health, Manhasset, NY
*Purpose: Though the chances of long term graft survival are highest with low KDPI kidneys, there is concern that after implementation of the new kidney…
2019 American Transplant Congress
Allogenic Islets Cure Diabetes Following Transplantation in Omental Pouch in a Non-Human Primate Model
J. Lei¹, H. Deng¹, K. Lee¹, C. Peters¹, G. Rickert¹, R. Ivy¹, M. Coronel², E. Yolcu³, H. Shirwan⁴, A. García⁵, J. Markmann¹
¹Surgery, Massachusetts General Hospital, Boston, MA, ²Surgery, Georgia Institute of Technology, Atlanta, GA, ³Institute for Cellular Therapeutics, University of Louisville School of Medicine, louisville, KY, ⁴Department of Microbiology and Immunology, University of Louisville School of Medicine, louisville, KY, ⁵School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA
*Purpose: In the current standard clinical transplant approach, islet cells are administered intravenously into the portal system where they lodge in the liver. This approach…
2019 American Transplant Congress
Transplanting Thoracic Organs From Hcv Donors To Uninfected Patients: Evaluation Of Lung Allografts
Y. Lo¹, R. F. Padera¹, H. R. Mallidi², H. J. Goldberg³, S. K. Singh², A. Coppolino, III⁴, L. R. Baden⁵, A. E. Woolley⁵
¹Pathology, Brigham and Womens Hospital, Boston, MA, ²Cardiac and Thoracic Surgery, Brigham and Womens Hospital, Boston, MA, ³Pulmonary, Brigham and Womens Hospital, Boston, MA, ⁴Thoracic Surgery, Brigham and Womens Hospital, Boston, MA, ⁵Infectious Diseases, Brigham and Womens Hospital, Boston, MA
*Purpose: Prior to the development of direct acting antiviral (DAA) therapy for hepatitis C virus (HCV), there was concern that patients who received lungs from…
2019 American Transplant Congress
Pancreas Transplant Alone Using Donation After Cardiac Death Donors Has Similar Outcomes As Donation After Brain Death Donors
K. Espinoza¹, D. Wall¹, K. L. Lentine², J. R. Wellen¹, D. Hammad¹, D. C. Brennan³, T. Alhamad¹
¹Washinton University in St. Louis, St. Louis, MO, ²Saint Louis University, St. Louis, MO, ³Johns Hopkins University, St. Louis, MO
*Purpose: While outcomes of pancreas transplants are improving, there is a persistent hesitancy to use pancreas organs procured in the context of donation after cardiac…