2019 American Transplant Congress
Breakthrough Invasive Fungal Infections in Solid Organ Transplant Patients Receiving Isavuconazole
University of California, San Francisco, San Francisco, CA
*Purpose: Isavuconazole (ISA) is a broad-spectrum triazole antifungal approved in 2015 for the treatment of invasive aspergillosis and mucormycosis. While it is increasingly used in…2019 American Transplant Congress
The Impact of Pneumonia after Liver Transplant
University of Massachusetts Medical School, Worcester, MA
*Purpose: Infection is a major cause of morbidity and mortality after organ transplantation and pneumonia is one of the most frequently encountered infections.*Methods: We conducted…2019 American Transplant Congress
Real-Life Food Safety Behavior and Incidence of Food-Borne Infections in Solid-Organ Transplant Recipients
*Purpose: Specific food safety measures are highly recommended in solid-organ transplant (SOT) recipients. However, the actual adherence of patients in real life and the impact…2019 American Transplant Congress
Damage-Associated Molecular Pattern Release and Toll-Like Receptor Activation during Cold Storage and Ex Vivo Reperfusion of Old Rat Livers
Department of Surgery, Duke University Medical Center, Durham, NC
*Purpose: Donor age is one of the most important predictive factors of graft outcome in liver transplantation. The aim of this study was to investigate…2019 American Transplant Congress
The Impact of Thrombin / Protease-Activated Receptor-1 Pathway in Hepatic Ischemia-Reperfusion Injury in Mice
*Purpose: Coagulation cascade is an important pathway in the pathophysiology of hepatic ischemia-reperfusion injury(IRI). Generation of thrombin is a critical factor of coagulation induced by…2019 American Transplant Congress
Increased Ratio of Circulating Tfh for Tfr Cells in Chronic Renal Allograft Dysfunction: A Pilot Study
West China Hospital OF Sichuan University, Chengdu, China
*Purpose: T follicular helper (Tfh) cells play a central role in contribution of B cell differentiation and antibody production. T follicular regulatory (Tfr) cells inhibit…2019 American Transplant Congress
Contribution of CD38 to Methionine Choline Deficient (MCD) Diet-Induced Liver Injury in Rats
Department of Cardiac Surgery, The Ohio State Univ. Medical Center, Columbus, OH
*Purpose: Nonalcoholic fatty liver disease (NAFLD) and associated non-alcoholic steatohepatitis (NASH) is a rising cause of end stage liver disease, increasing the need for liver…2019 American Transplant Congress
Normothermic Ex-Situ Liver Perfusion Parameters of Liver Viability in a Porcine Model of Liver Transplantation with Marginal Grafts
1Toronto General Hospital, Toronto, ON, Canada, 2University of Nicolaus Copernicus, Torun, Poland
*Purpose: Evaluate parameters of liver viability during normothermic ex-situ liver perfusion (NEsLP) prior to transplantation.*Methods: In this study, we investigated prior assessed parameters and new…2019 American Transplant Congress
Prevalence of Donor Specific Antibody in Heart Transplant Recipients with Antibody-Mediated Rejection as Compared to Abnormal Intragraft mRNA Transcripts by Molecular Microscope System
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: Antibody-mediated rejection (AMR) is defined by pathologic evaluation of endomyocardial biopsy (EMB) for both histologic and immunopathologic components. Detectable donor specific antibodies (DSAs) in…2019 American Transplant Congress
Is Muscular Dystrophy A Contraindication To Heart Transplantation?
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: Patients with muscular dystrophy may have an associated cardiomyopathy, resulting in advanced heart failure requiring transplantation. However, the skeletal muscle dysfunction can result in…
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