ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Is Bariatric Surgery Feasible in the Setting of Liver and Kidney Transplants?

    L. M. Potter, A. Saharia, C. Mobley, K. Lunsford, M. Hobeika, N. Tariq, H. Podder, A. O. Gaber, R. M. Ghobrial

    Liver Transplant and Hepatobiliary Surgery, The Houston Methodist Hospital, Houston, TX

    *Purpose: Bariatric surgery benefits obese patients by promoting weight loss, improving quality of life, and reducing morbidity and mortality rates. There is concern, however, that…
  • 2019 American Transplant Congress

    The Liver Frailty Index is Associated with Current and Subsequent Disability in Liver Transplant Candidates

    J. C. Lai, J. L. Dodge, C. E. McCulloch, K. E. Covinsky, J. P. Singer

    University of California, San Francisco, San Francisco, CA

    *Purpose: The Liver Frailty Index (LFI) was developed to capture the effects of malnutrition and muscle wasting in patients with cirrhosis awaiting liver transplantation (LT).…
  • 2019 American Transplant Congress

    Impact of Multidrug-Resistant Organisms among Donors on Organ Utilization

    J. A. Anesi1, E. Lautenbach1, J. H. Han1, D. H. Lee2, H. Clauss3, A. Climaco4, R. Hasz5, E. Molnar3, D. Alimenti1, S. West5, W. B. Bilker1, P. Tolomeo1, E. A. Blumberg1

    1University of Pennsylvania, Philadelphia, PA, 2Drexel University College of Medicine, Philadelphia, PA, 3Temple University, Philadelphia, PA, 4Albert Einstein Medical Center, Philadelphia, PA, 5Gift of Life Donor Program, Philadelphia, PA

    *Purpose: Though transplant guidelines recommend exercising caution when considering donor organs that may be infected or colonized with multidrug-resistant organisms (MDROs), the true impact of…
  • 2019 American Transplant Congress

    Comparison of Proton Pump Inhibitors versus Histamine-2-Receptor Antagonists on Clostridium difficile Rates in Liver Transplant Recipients

    S. Wiehe, K. Roach, A. Qamar

    Lahey Hospital and Medical Center, Burlington, MA

    *Purpose: To determine if there is a difference in 90 day Clostridium difficile infection (CDI) rates before and after the stress ulcer prophylaxis (SUP) protocol…
  • 2019 American Transplant Congress

    Cholecystitis in High-Acuity Patients Undergoing Liver Transplantation: A Five-Year Analysis of Incidence, Causes and Impact

    D. S. Graham, T. Ito, M. M. Lu, J. DiNorcia, V. G. Agopian, H. Yersiz, D. G. Farmer, R. W. Busuttil, F. M. Kaldas

    Dumont-UCLA Liver Transplant Center, Department of Surgery, UCLA School of Medicine, Los Angeles, CA

    *Purpose: While the incidence of gallbladder pathology is well described in the general population, there is almost no data on cholecystitis in liver transplant candidates…
  • 2019 American Transplant Congress

    Hypothermic Machine Perfusion Protects Donation After Cardiac Deathliver Graft Through Gstm1-mediated Cytochrome P450 Exogenous Substance Metabolism Pathway

    W. Liang, S. Ye, Z. Zhong, Q. Hu, Y. Wang, Q. Ye

    Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases, Wuhan, China

    *Purpose: Donation after cardiac death (DCD) is the mainly resource to relieve organ-transplantation shortage. Our previous research have confirmed that the function of DCD liver…
  • 2019 American Transplant Congress

    Transfer of Healthy Mitochondria in Established Ischemic Injury Reduces Progression to Interstitial Fibrosis and Tubular Atrophy

    A. Bajwa1, V. Bontha1, D. Maluf1, J. Eason2, V. Mas3

    1UTHSC, Memphis, TN, 2Director of Transplant Institute, Memphis, TN, 3Director of Transplant Research Institute, Memphis, TN

    *Purpose: Ischemia induces altered bioenergetics with increased mitochondrial swelling and reactive oxygen species (ROS) and ultimately degradation of cellular function. Therapeutic interventions that target to…
  • 2019 American Transplant Congress

    Characterization of Circulating T-cell Specific Exosomes during Acute Rejection in Murine Heart Transplantation Model

    R. Hu1, V. Korutla1, L. Korutla1, S. Rostami1, A. Habertheuer1, S. Addya2, J. Harmon1, P. Zielinski1, S. Reddy1, A. Freas1, C. Ram1, A. Naji1, P. Vallabhajosyula1

    1Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, 2Thomas Jefferson University, Philadelphia, PA

    *Purpose: Exosomes are nanoparticles (30-200nm) released by many cell types. They carry nucleic acid and proteins that may reflect conditional changes in their tissue counterparts.…
  • 2019 American Transplant Congress

    Use of TruGraf Serial Testing for Confirming Stability in Kidney Transplant Patients with Stable Renal Function

    V. Peddi1, C. Schieve2, S. Rose2, M. First2

    1California Pacific Med Ctr, San Francisco, CA, 2Transplant Genomics Inc, Mansfield, MA

    *Purpose: The objectives of this study were to model serial TruGraf testing in stable kidney transplant recipients and to demonstrate the potential clinical utility of…
  • 2019 American Transplant Congress

    Need of a New Formula to Estimate Creatinine Clearance in Immediate Post Kidney Transplant Period with Functioning Allograft

    A. B. Jain1, U. Farooq2, A. Brooks1, T. Dohi1, F. Butt1, Z. Kadry1

    1Surgery ( Transplant), Penn State Milton Hershey Medical Center, Hershey 17033, PA, 2Medicine( Neprhology), Penn State Milton Hershey Medical Center, Hershey, PA

    *Purpose: Introduction: Post kidney transplant (KTx), with functioning renal allograft, serum creatinine continues to decrease at a variable rate until it stabilizes after a few…
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