2019 American Transplant Congress
Treatment of Pseudomonas Infection with Beta-Lactams Including Ceftolozane-Tazobactam in Solid Organ Transplant Recipients
*Purpose: Ceftolozane/Tazobactam (CT) is a potent anti-pseudomonal agent with broad gram-negative activity. Our academic medical center recommends the use of CT for patients with a…2019 American Transplant Congress
Erk-elk1-mir-711 Signalling In Cardiac Ischemia Reperfusion Injury In Heart Transplantation
Pathology, University of Western Ontario, London, ON, Canada
*Purpose: This study aims to discover new molecular mechanisms involved in and to develop new treatment for preventing ischemia reperfusion injury in heart transplantation.*Methods: The…2019 American Transplant Congress
Microvascular Rarefaction and Long-Term Graft Dysfunction in Kidney Transplant Recipients with Delayed Graft Function
*Purpose: Delayed graft function (DGF), or acute kidney injury in the perioperative period, is associated with decreased kidney graft survival.*Methods: As animal studies suggest that…2019 American Transplant Congress
The Molecular Profile of Kidney Allografts Unveil Specific Biomarkers for Subclinical Acute Rejection (SAR). Towards an Early Detection and a Targeted Treatment
Schena Foundation, Valenzano-Bari, Italy
*Purpose: SAR diagnosed by protocol biopsy is an independent risk factor for chronic allograft injury. We organized a molecular study on 24 AB0 compatible cadaveric…2019 American Transplant Congress
Post-Transplant Lymphopenia is Associated with Higher Risk of Graft Failure, Death and Viral Infections
*Purpose: The transplantation field needs biomarkers to assess the level of immunosuppression. In this study, we aimed to analyze the independent correlation between the number…2019 American Transplant Congress
Use of Anti-Vimentin Antibodies as a Possible Marker for Graft Dysfunction Following Renal Transplant, a Prospective Study
*Purpose: In our previously published work, we showed that presence of anti-vimentin antibodies (AVA) after renal transplant correlated with early IFTA (Interstitial Fibrosis and Tubular…2019 American Transplant Congress
Nephrotoxicity Caused by Calcineurin Inhibitors is Meditated by BAX, NOL3 and XIAP Apoptotic Genes Dysregulation
*Purpose: Calcineurin inhibitors (CNI) remain the most effective and widely used immunosuppressive agents in kidney transplantation. Nephrotoxicity is a major secondary effect, and renal biopsy…2019 American Transplant Congress
Reference Ranges Donor-Derived Cell-Free DNA in a Heart Transplant Population
1Saint Luke's, Kansas City, MO, 2CareDx, Brisbane, CA, 3University of Los Angeles, Los Angeles, CA
*Purpose: Elevations in donor-derived cell-free DNA (dd-cfDNA) ≥0.20 % in heart transplant recipients (HTR) has been shown to be associated with a probability of acute…2019 American Transplant Congress
Liver Allograft Provides Protection Against Cardiac Allograft Rejection In Combined Heart And Liver Transplantation
*Purpose: Combined heart-liver transplant (CHLT) is indicated for patients with combination of heart and liver disease or amyloid heart disease for whom liver transplant can…2019 American Transplant Congress
Trends in Utilization of Deceased Donor Kidneys Based on Donor Hep C Antibody and Nucleic Acid Status
*Purpose: HCV nucleic acid testing (NAT) testing for deceased donors (DD) has been routine since 2015. We intended to look at utilization/discard rates based on…
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