ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Phylogenetic Analysis of the Epstein Barr Virus Nuclear Antigen-1 and Associated Correlates among Canadian Transplant Patients

    M. Abdulnoor1, S. Isabel1, T. Paton1, N. Khodai-Booran1, T. Schechter1, P. Birk2, T. Blydt-Hansen3, B. Foster4, S. Mital1, V. Phan5, S. Urschel6, G. Casallo1, T. Papaz1, L. Hamiwka7, S. Min1, U. Allen1

    1University of Toronto, Toronto, ON, Canada, 2University of Manitoba, Winnipeg, MB, Canada, 3University of British Columbia, Vancouver, BC, Canada, 4McGill University, Montreal, QC, Canada, 5University of Montreal, Montreal, QC, Canada, 6University of Alberta, Edmonton, AB, Canada, 7University of Calgary, Calgary, AB, Canada

    *Purpose: The effect of the genetic diversity of the Epstein-Barr virus (EBV) on clinical outcomes in the transplant setting is important to study. We examined…
  • 2019 American Transplant Congress

    Infective Complications after Renal Transplantation – A Single Centre Experience Comparing Alemtuzumab to Basiliximab Induction

    R. Czajka, M. Welberry Smith, M. Gittus, E. Lindley, M. Vernon

    Renal Medicine, St James' University Hospital, Leeds, United Kingdom

    *Purpose: Our centre predominantly uses alemtuzumab as induction immunosuppression for renal transplantation. We examined infective complications after renal transplantation, comparing different induction, and maintenance, immunosuppression…
  • 2019 American Transplant Congress

    Phenotype and Course of Renal Tubular Cell Death during Cold Ischemia versus Cold Ischemia Followed by Transplant

    S. Jain1, R. Plenter2, T. Nydam2, A. Jani1

    1Renal Division, University of Colorado, Aurora, CO, 2Transplant Microsurgery Program, University of Colorado, Aurora, CO

    *Purpose: Treatments of Delayed graft function (DGF) are lacking. Prolonged cold ischemia (CI) is a risk factor for DGF but the pathways by which CI…
  • 2019 American Transplant Congress

    Histone Deacetylase-8 (HDAC8) Inhibition is Protective in a Murine Model of Renal Ischemia Reperfusion Injury (IRI)

    P. T. Hernandez1, S. J. Concors1, D. D. Aufhauser1, L. Krumeich1, Z. Wang1, G. Ge1, A. Beeler2, M. Levine1, W. Hancock3

    1Hospital of the University of Pennsylvania, Philadelphia, PA, 2Chemistry, Boston University, Boston, MA, 3Children's Hospital of Philadelphia, Philadelphia, PA

    *Purpose: IRI is a major source of morbidity after renal transplantation, contributing to poor transplant outcomes and decreased graft survival. Histone deacetylases (HDACs) are enzymes…
  • 2019 American Transplant Congress

    Urinary Podocin mRNA as Predictor of Renal Allograft Function Decline

    A. Naik1, J. Aqeel1, D. Cibrik2, M. Samaniego3, L. Wickman1, S. Wang1, M. Chowdhury1, R. Wiggins1

    1University of Michigan, Ann Arbor, MI, 2University of Kansas, Kansas City, KS, 3Henry Ford, Detroit, MI

    *Purpose: Traditional biomarkers (such as proteinuria, 1year eGFR) as well as validated risk prediction tools such as the Birmingham Risk Score predict risk of ESRD.…
  • 2019 American Transplant Congress

    The Value of SCS Perfusate Biomarkers for Predicting DGF of DCD Donor Kidneys

    X. Li, W. Wang, X. Zhang

    Beijing Chaoyang Hospital, Capital Medical University, Beijing, China

    *Purpose: To explore the possibilities of simple cold stored(SCS) perfusate biomarkers predicting delayed graft function(DGF) in donor of cardiac death (DCD) kidneys.*Methods: A total of…
  • 2019 American Transplant Congress

    Chemokine Ligand 14 is a Novel Therapeutic Target in Kidney Fibrosis

    S. Lee1, Y. Kim1, J. Moon1, H. Lee1, S. Han1, J. Lee2, R. Cha3, D. Kim1, C. Lee4, K. Kim5, Y. Kim1, S. Yang6

    1Internal Medicine, Seoul National University Hospital, Seoul, Korea, Republic of, 2Internal Medicine, Boramae Medical Center, Seoul, Korea, Republic of, 3Internal Medicine, National Medical Center, Seoul, Korea, Republic of, 4Internal Medicine, Cheju Halla University Hospital, Jeju, Korea, Republic of, 5Biomedical Science, Seoul National University, Seoul, Korea, Republic of, 6Seoul National University College of Medicine, Seoul, Korea, Republic of

    *Purpose: Chemokine ligand 14 (CCL14), a ligand for CCR1, has been known as a M2 polarizing marker and chemotactic cytokine, which is expressed by fibroblast,…
  • 2019 American Transplant Congress

    Outcome Of Late Biopsy-negative Rejection After Heart Transplantation

    M. Kittleson, J. Patel, E. Kransdorf, S. Dimbil, R. Levine, J. A. Kobashigawa

    Cedars-Sinai Smidt Heart Institute, Los Angeles, CA

    *Purpose: Biopsy-negative rejection (BNR) is an entity where the endomyocardial biopsy (EMB) shows no findings of rejection, but there is proven cardiac dysfunction i.e. low…
  • 2019 American Transplant Congress

    Outcome Of Left Main Stenting After Heart Transplantation

    S. Dimbil, J. Patel, B. Azarbal, M. Kittleson, R. Levine, D. H. Chang, J. A. Kobashigawa

    Cedars-Sinai Smidt Heart Institute, Los Angeles, CA

    *Purpose: Cardiac allograft vasculopathy (CAV) is one of the major factors limiting long-term survival after HTx. The use of angioplasty and drug-eluting stents is common…
  • 2019 American Transplant Congress

    Intravenous Methamphetamine Does Not Appear To Be A Contraindication For Heart Donation In Heart Transplantation

    A. Velleca, J. Patel, M. Kittleson, R. Levine, S. Dimbil, S. Mersola, M. Hamilton, F. Esmailian, J. A. Kobashigawa

    Cedars-Sinai Smidt Heart Institute, Los Angeles, CA

    *Purpose: Intravenous methamphetamine (IV meth) use in potential heart donors has been of concern due to the possibility of methamphetamine cardiomyopathy and transmission of infections.…
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