ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Post-transplant Lymphoproliferative Disorder Following Intestine Transplantation: Contemporary Single Center Experience

    A. Zimmerman, J. Hawksworth, A. Kroemer, P. Radkani, K. Khan, S. Kaufman, N. Yazigi, S. Subramanian, T. Fishbein, C. Matsumoto

    Georgetown Transplant Institute, MedStar Georgetown University Hospital, Washington, DC

    *Purpose: The purpose of this study was to examine the characteristics and risk factors for PTLD after intestinal transplant.*Methods: Retrospective review of intestinal transplant recipients…
  • 2019 American Transplant Congress

    The Rapidly Aging Population of Liver Transplant Patients with Hepatocellular Carcinoma

    J. B. Rubin, G. Cullaro, N. Mehta, J. C. Lai

    Division of Gastroenterology & Hepatology, UCSF, San Francisco, CA

    *Purpose: Hepatocellular carcinoma (HCC) is the fastest rising cause of cancer-related mortality in the US and a leading indication for liver transplant (LT). Direct acting…
  • 2019 American Transplant Congress

    Organ Procurement Organization Performance is Not Related to Educational Spending

    J. P. Roberts1, J. Bragg-Gresham2, P. Held3

    1Univ of California-San Francisco, San Francisco, CA, 2Nephrology, University of Michigan, Ann Arbor, MI, 3Stanford University, Stanford, CA

    *Purpose: We examined the educational spending by OPOs in relationship to OPO performance metrics.*Methods: Data sources: OPO Cost Reports (CMS 216-94 Form), SRTR OPO Specific…
  • 2019 American Transplant Congress

    Clinical Features and Prognosis of Diffuse Intrahepatic Biliary Stricture in Adult ABO-Incompatible Living Donor Liver Transplantation

    J. Kwon, G. Song, S. Hwang, K. Kim, C. Ahn, D. Moon, T. Ha, D. Jung, G. Park, Y. Yoon, H. Cho, I. Jeong, J. Choi, S. Yoo, S. Lee

    Division of Liver Transplantation and Hepatobiliary Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea, Republic of

    *Purpose: Despite the advancement in desensitization protocol, diffuse intrahepatic biliary stricture (DIHBS), an attenuated form of antibody mediated rejection (AMR), remains an unresolved problem. As…
  • 2019 American Transplant Congress

    Differences in the Cost of Recovering Organs over Time

    J. P. Roberts1, J. Bragg-Gresham2, P. Held3

    1Univ of California-San Francisco, San Francisco, CA, 2Univ of Michigan, Ann Arbor, CA, 3Stanford University, Stanford, CA

    *Purpose: To report on the level and changes over time in the OPOs’ cost of recovering deceased donor organs (kidneys; livers; hearts; and lungs).*Methods: Cost…
  • 2019 American Transplant Congress

    Donor Brain Death Affects Tolerance Induction in Non-Human Primates

    W. Sommer1, J. M. O2, K. B. Pruner3, J. T. Paster3, A. Bean3, A. Dehnadi3, I. M. Hanekamp3, I. Rosales4, R. N. Smith4, R. B. Colvin4, G. Benichou3, J. S. Allan3, T. Kawai3, J. C. Madsen5

    1Department of Cardiothoracic Surgery, Hannover Medical School, Hannover, Germany, 2Center for Transplantation Sciences, Massachusets General Hospital, Boston, MA, 3Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, 4Department of Pathology, Massachusetts General Hospital, Boston, MA, 5Center fro Transplantation Sciences, Massachusetts General Hospital, Boston, MA

    *Purpose: Induction of durable allograft acceptance in combined heart/kidney transplantation in non-human primates is possible by applying a mixed chimerism-based conditioning protocol. However, the impact…
  • 2019 American Transplant Congress

    Acquired Resistance to Transplantation Tolerance as a Result of Prior Pregnancy Requires B Cells

    D. V. Tran, A. N. Suah, S. Khiew, J. S. Young, Q. Wang, D. Yin, M. Alegre, A. S. Chong

    Departments of Surgery and Medicine, University of Chicago, Chicago, IL

    *Purpose: Clinical data suggest allogeneic pregnancy is a sensitizing event; however, data from mouse models suggests it induces fetal-specific regulatory T cell (Treg) expansion and…
  • 2019 American Transplant Congress

    Perioperative Cardiac Xenograft Dysfunction after Orthotopic Transplantation is for Real

    M. Mohiuddin1, A. Singh1, L. DiChiacchio1, D. Kaczorowski1, B. Lewis1, T. Zhang1, F. Sentz1, I. Tatarov1, D. Parsell1, P. Odonkor1, E. Strauss1, B. Williams1, K. Deatrick1, D. Ayares2, B. Griffith1, S. Bartlett1

    1Department of Surgery, University of Maryland Baltimore, Baltimore, MD, 2Revivicor, Inc, Blacksburg, VA

    *Purpose: After successful prolongation of cardiac xenograft survival in a heterotopic position, the next step is to evaluate genetically engineered (GE) pig hearts for their…
  • 2019 American Transplant Congress

    Validation Of The Optimized Prediction Of Mortality (Opom) Machine Learning Model For Non-hepatocellular Carcinoma Candidates Awaiting Liver Transplant

    L. Lau1, X. Xie2, F. Jia2, P. D. Greig1, T. C. Chan2

    1Multi-Organ Transplant, Department of Surgery, University of Toronto, Toronto, ON, Canada, 2Mechanical and Industrial Engineering, University of Toronto, Toronto, ON, Canada

    *Purpose: Currently the Model for End-Stage Liver Disease (MELD) is used to rank candidates for liver transplant in many jurisdictions. However, MELD does not provide…
  • 2019 American Transplant Congress

    CMV Risk Status Remains a Relevant Risk Factor for Long-Term Outcomes

    G. Karadkhele, W. Zhang, C. P. Larsen

    Emory University, Atlanta, GA

    *Purpose: Intensification of immunosuppression using T cell depleting induction has reduced rates of acute cellular rejection after kidney transplantation. Belatacept, a first in class T…
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