ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Ninety-Day Complications in 214 Intestinal Transplant Patients: A Calvien-Dindo Analysis and Assessment of Long Term Outcomes

    A. Zimmerman, J. Hawksworth, A. Kroemer, P. Radkani, K. Khan, S. Kaufman, N. Yazigi, S. Subramanian, T. Fishbein, C. Matsumoto

    Georgetown Transplant Institute, MedStar Georgetown University Hospital, Washington, DC

    *Purpose: The purpose of this study was to examine the 90-day complications that occurred after intestinal transplantation and to determine whether they effect 5-year patient…
  • 2019 American Transplant Congress

    The Influential Yet Highly Variable Role of Biopsy Findings on Kidney Offer Acceptance Decisions: An Organ Offer Simulation Study

    D. Stewart1, J. Rosendale1, H. McGehee1, I. Hall2, G. Gupta3, K. Reddy4, B. Kasiske5, K. Andreoni6, D. Klassen1

    1UNOS, Richmond, VA, 2Univ of Utah, Salt Lake City, UT, 3VCU, Richmond, VA, 4Mayo, Phoenix, AZ, 5HCMC, Minneapolis, MN, 6Univ of Florida, Gainesville, FL

    *Purpose: The use of procurement biopsies (Bx) to assess kidney quality is controversial. ‘Biopsy findings’ is an often cited discard reason, yet the association between…
  • 2019 American Transplant Congress

    Towards Human Leukocyte Antigen Immunogenicity Assessment at the Individual Patient Level

    H. Copley1, H. McDowell2, D. Pinelli2, A. R. Tambur2, V. Kosmoliaptsis1

    1Department of Surgery, University of Cambridge, Cambridge, United Kingdom, 2Department of Surgery, Feinberg School of Medicine, Comprehensive Transplant Center, Northwestern University, Chicago, IL

    *Purpose: Allorecognition of donor HLA and induction of humoral alloimmunity is a major cause of graft loss after solid-organ transplantation. Current approaches to study molecular…
  • 2019 American Transplant Congress

    The Use of High Volume Perioperative Normal Saline Increases the Risk of Delayed Graft Function after Kidney Transplantation

    K. Kolodzie1, O. S. Cakmakkaya2, E. S. Boparai3, M. Tavakol4, J. Feiner1, C. U. Niemann5

    1Anesthesia & Perioperative Care, University of California San Francisco, San Francisco, CA, 2Dept. of Medical Education, University Istanbul – Cerrahpasa, Istanbul, Turkey, 3School of Medicine, George Washington University, Washington, DC, 4Dept. of Surgery, Division of Transplantation, University of California San Francisco, San Francisco, CA, 5Anesthesia & Perioperative Care, and Dept. of Surgery, Division of Transplantation, University of California San Francisco, San Francisco, CA

    *Purpose: Metabolic and physiologic effects of high volume perioperative Normal Saline (NS) resuscitation are well described, but the impact on delayed graft function (DGF) remains…
  • 2019 American Transplant Congress

    Differences in the Cost of Kidney Organ Recovery by Organ Procurement Organization Size

    P. J. Held1, J. Bragg-Gresham2, J. P. Roberts3

    1Stanford University, Stanford, CA, 2Univ of Michigan, Michigan, MI, 3Univ of California-San Francisco, San Francisco, CA

    *Purpose: Economic theory suggests that there should be an initial decrease in costs of products as production levels increase. Using data from independent OPOs we…
  • 2019 American Transplant Congress

    B7H1 Expression is Crucial for Tolerance Induction in Mouse Liver Transplantation

    M. Morita1, S. Datta1, C. Miller2, T. Hamilton1, K. Hashimoto3

    1Inflammation & Immunity, Lerner Research Institution, Cleveland, OH, 2General surgery, Liver Transplant Center, Cleveland Clinic, Cleveland, OH, 3General Surgery, Liver Transplant Center, Cleveland Clinic, Cleveland, OH

    *Purpose: Following organ transplantation, lifelong immunosuppressive treatment is required and it causes severe side effects. Induction of donor specific tolerance is ideal, which actually spontaneously…
  • 2019 American Transplant Congress

    Dichotomous Role Of Donor T Cells In The Efficacy Of Tolerogenic Therapies For Transplant Rejection

    M. Iglesias Lozano, D. Bibicheff, M. Chicco, G. Brandacher, G. Raimondi

    Plastic Surgery, Johns Hopkins University, Baltimore, MD

    *Purpose: Costimulation blockade-based regimens are a promising strategy to promote transplant tolerance. However, their efficacy is affected by multiple factors, many of which remain unknown.…
  • 2019 American Transplant Congress

    TCR Transgenes to Understand Human Xenotolerance Induction

    G. Nauman, C. Borsotti, N. Danzl, M. Khosravi-Maharlooei, H. Li, E. Chavez, Y. Yang, M. Sykes

    Columbia Center for Translational Immunology, New York, NY

    *Purpose: Swine thymus transplantation is a promising approach to clinical tolerance for pig-to-human xenotransplantation. In humanized mice, a swine thymus graft supports de novo selection…
  • 2019 American Transplant Congress

    The Graft and Patient Survival of Kidney Transplantation According to Ethnicity in US Kidney Transplant Recipients

    H. Shin1, Y. Kim1, Y. Jung1, H. Rim1, A. Chandraker2

    1Internal Medicine, Kosin University College of Medicine, Gospel Hospital, Busan, Korea, Republic of, 2Internal Medicine, Harvard Medical School Brigham & Women's Hospital, Boston, MA

    *Purpose: African American kidney transplant recipients experience disproportionately high rates of graft loss. The aim of this analysis was to use a UNOS data set…
  • 2019 American Transplant Congress

    Long-Term Outcomes Following Uncontrolled Donation after Cardiac Death Kidney Transplantation: Opportunity for Increasing Donor Pool?

    R. A. Choudhury, K. Prins, D. Yoeli, H. B. Moore, T. L. Nydam

    Transplant Surgery, University of Colorado, Aurora, CO

    *Purpose: Uncontrolled donation after cardiac death (uDCD) represents an underutilized source of donors in the United States. However, controversy surrounding the long-term durability of uDCD…
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