Am J Transplant, Volume 19, Suppl 3 Archives - Page 150 of 214 - ATC Abstracts

2019 American Transplant Congress
The End of Non-Directed Living Kidney Donation: The National Kidney Registry’s Family Voucher Program
M. Cooper¹, D. Leeser², S. Flechner³, J. Verbesey¹, M. Ronin⁴, G. Hil⁴, A. Waterman⁵, J. Veale⁵
¹Georgetown Transplant Institute, Washington, DC, ²East Carolina University, Greenville, NC, ³Cleveland Clinic, Cleveland, OH, ⁴National Kidney Registry, New York, NY, ⁵UCLA, Los Angeles, CA
*Purpose: The continued growth of the National Kidney Registry’s (NKR) Voucher program has extended Kidney Paired Donation (KPD) to include chronological incompatibility which is facilitating…
2019 American Transplant Congress
Improving Medication Adherence and Outcomes in Adult Kidney Transplant Patients Using SystemCHANGE^TM: Results of the Medication Adherence Given Individual Change (MAGIC) Randomized Clinical Trial
M. R. Wakefield¹, C. M. Ashbaugh², L. Remy³, D. Aholt³, C. Miller³, S. Ye³, D. K. Hathaway⁴, D. Clark⁴, V. S. Staggs⁵, K. Goggin⁶, R. J. Ellis⁷, C. L. Russell³
¹Surgery/Urology, University of Missouri School of Medicine, Columbia, MO, ²Transplant, University of Missouri Health Care, Columbia, MO, ³School of Nursing and Health Studies, University of Missouri-Kansas City, Kansas City, MO, ⁴College of Nursing, University of Tennessee HSC, Memphis, TN, ⁵Health Services and Outcomes Research, Children's Mercy Kansas City, Kansas City, MO, ⁶Health Services and Outcomes Research, Children's Mercy Kansas City and Schools of Medicine and Pharmacy, University of Missouri-Kansas City, Kansas City, MO, ⁷School of Nursing, Indiana University, Indianapolis, IN
*Purpose: Medication non-adherence is an obdurate problem associated with poor outcomes and staggering costs. Even with multi-faceted interventions, effect sizes reported in meta-analyses of medication…
2019 American Transplant Congress
The Benefit of Kidney Transplantation over the Waitlist Depends on the Patient’s Comorbidities
A. Andrade Izquierdo¹, J. V. Reusing Jr¹, V. Onusic¹, F. Agena¹, F. C. Lemos¹, F. de Paula¹, F. Gerab², E. David-Neto¹
¹Renal Transplantation Service, Hospital das Clínicas - University of São Paulo School of Medicine, Sao Paulo, Brazil, ²Department of Mathematics, FEI University, Sao Paulo, Brazil
*Purpose: This study aimed to determine the impact of different comorbidities to the survival benefit of Kidney Transplantation (KTx) compared to waitlisted (WL) patients in…
2019 American Transplant Congress
Donation after Cardiac Simultaneous Liver-Kidney: An Updated Perspective
R. Nunez, P. Morgan, A. Mathur, K. S. Reddy, A. Moss, B. Aqel, C. Jadlowiec
Mayo Clinic AZ, Phoenix, AZ
*Purpose: Historically, the outcomes from donation after cardiac death (DCD) donors have been shown to be inferior as compared to those of donation after brain…
2019 American Transplant Congress
Selective CD28 Blockade-Mediated Inhibition of T Follicular Helper Cell and DSA Responses is CTLA-4 Dependent
G. M. La Muraglia II, M. L. Ford, I. R. Badell
Emory Transplant Center, Atlanta, GA
*Purpose: Clinical costimulation blockade of the CD28 pathway in the form of CTLA-4Ig has shown the ability to attenuate T cell dependent DSA responses. However,…
2019 American Transplant Congress
Hepatitis C Positive Donor to Negative Recipient Kidney Transplantation: A Single Center Real World Experience
N. Jandovitz, V. Nair, E. Grodstein, E. Molmenti, A. Fahmy, M. Bhaskaran, L. Teperman
North Shore University Hospital, Manhasset, NY
*Purpose: Several small studies have shown that transplanting a hepatitis C virus (HCV) negative recipient with a HCV positive donor is feasible in a research…
2019 American Transplant Congress
Organ Resilience Contributes to Different Impact of Delayed Graft Function (DGF) on Graft Survival in Kidneys Donated by Brain Death (DBD) and Circulatory Death Donors (DCD)
M. J. de Kok, A. F. Schaapherder, L. G. Wijermars, D. K. de Vries, J. L. Lindeman
Transplantation Center, LUMC, Leiden, Netherlands
*Purpose: Despite a tripled higher incidence of DGF in DCD kidney grafts compared to DBD kidney grafts, large studies show equivalent long-term graft survival with…
2019 American Transplant Congress
Concentric Circles, One Year in: Concentrated Organ Discard and Waitlist Deaths in High Traffic Areas
R. J. Lynch¹, S. Karp², W. Chapman³
¹Emory, Atlanta, GA, ²Vanderbilt, Nashville, TN, ³Washington University St. Louis, St. Louis, MO
*Purpose: Lung transplantation was the first organ system to entirely dispense with Donor Service Areas (DSAs) and Regions in favor of 250 nautical mile (NM)…
2019 American Transplant Congress
Single Cell Analysis of Kidney Allograft Rejection
C. M. Castro-Rojas¹, K. M. Roskin², C. G. Moore², B. Abu Jawdeh³, N. Salomonis², R. R. Alloway⁴, E. Woodle⁴, D. A. Hildeman¹
¹Immunobiology, Cincinnati Children's Hospital, Cincinnati, OH, ²Biomedical Informatics, Cincinnati Children's Hospital, Cincinnati, OH, ³Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, ⁴Transplantation, University of Cincinnati College of Medicine, Cincinnati, OH
*Purpose: Rejection therapies (corticosteroids and antilymphocyte globulins) have not changed in over 50 years. In part this is due to a knowledge deficit of signaling…
2019 American Transplant Congress
Timing and Donor-Specific Antibodies, but Not C4d Deposition, Determine Leukocyte Infiltration in Renal Allograft Biopsies with the Histological Picture of Antibody-Mediated Rejection
J. Callemeyn¹, A. Senev¹, E. Lerut², M. Coemans¹, D. Kuypers¹, W. Gwinner³, M. Essig⁴, D. Anglicheau⁵, P. Marquet⁶, M. Naesens¹
¹Department of Microbiology and Immunology, KU Leuven, Leuven, Belgium, ²Department of Pathology, University Hospitals Leuven, Leuven, Belgium, ³Department of Nephrology, Hannover Medical School, Hannover, Germany, ⁴Department of Nephrology, Dialysis and Transplantation, University of Limoges, Limoges, France, ⁵Necker-Enfants Malades Institute, French National Institute of Health and Medical Research U1151, Paris, France, ⁶U850 INSERM, University of Limoges, Limoges, France
*Purpose: Diagnosis of antibody-mediated rejection following kidney transplantation can be challenging, given the limited specificity of individual histological parameters and time-dependent occurrence of histological confounders.…