Am J Transplant, Volume 19, Suppl 3 Archives - Page 148 of 214 - ATC Abstracts

2019 American Transplant Congress
Evaluating Liver Regeneration during Normothermic Machine Perfusion in Hepatectomized Rat Liver Model
M. Aburawi¹, S. Mert¹, E. Hafiz², P. Mahboub¹, H. Yeh¹, K. Uygun¹, J. Markmann¹
¹Surgery, Massachusetts General Hospital, Boston, MA, ²Pathology and Electron Microscopy, Theodor Bilharz Research Institute, Cairo, Egypt
*Purpose: Realizing the liver’s unique ability to regenerate, this ongoing study examines Normothermic Machine Perfusion (NMP) as a promising platform for evaluating & potentially simulating…
2019 American Transplant Congress
PD-1+CD3+CD4-CD8- (Double Negative T-cells) Are Early Responders during Kidney Ischemia Reperfusion Injury and Regulated by Non-Classical MHC Molecules
M. Sadasivam, S. Noel, S. Lee, J. Gong, A. Hamad, H. Rabb
Johns Hopkins University and School of Medicine, Baltimore, MD
*Purpose: Unconventional T-cells (e.g. Tregs and γδT-cells) are increasingly recognized for their roles in maintaining homeostasis and protecting non-lymphoid tissues against injury/stress. Double negative (DN)…
2019 American Transplant Congress
Histologic Ischemia Reperfusion Injury in Liver Transplantation: A Large Single Center Experience
F. M. Kaldas, T. Ito, S. Younan, J. Aziz, M. Lu, V. G. Agopian, J. DiNorcia III, H. Yersiz, D. G. Farmer, R. W. Busuttil
Department of Surgery, The Dumont-UCLA Transplant Center, Los Angeles, CA
*Purpose: Ischemia Reperfusion Injury (IRI) is known to adversely affect graft outcomes in Liver Transplantation (LT). Large series examining the significance of IRI found on…
2019 American Transplant Congress
Prognostic Value of C3d Fixing Preformed Donor-Specific Antibody in Crossmatch-Positive Living Kidney Transplantation
K. Miyake¹, M. Okumi¹, Y. Kakuta¹, K. Unagami², M. Furusawa¹, H. Ishida², K. Tanabe¹
¹Urology, Tokyo Women's Medical University, Sinjuku, Japan, ²Organ Transplant Medicine, Tokyo Women's Medical University, Sinjuku, Japan
*Purpose: The occurrence of acute antibody-mediated rejection (ABMR) was higher in flow cytometric crossmatch (FCXM)-positive patients despite desensitization, and complement binding ability of donor specific…
2019 American Transplant Congress
Living Donor Conversion Rates as a Quality Measure for Kidney Program Efficiency for Both New Referrals and Existing Listed Candidates
E. Woodle¹, C. Siemers², B. Woodle³, C. King², R. Alloway¹, S. Tremblay¹
¹U of Cincinnati, Cincinnati, OH, ²UC Health, Cincinnati, OH, ³U of Arkansas, Little Rock, AR
*Purpose: Arguably the most important achievement for renal failure patients is identification of a living donor (LD)and transplantation with a LD kidney. Given these considerations…
2019 American Transplant Congress
Prospective Multi-Regional Study of Down-Staging of Hepatocellular Carcinoma to within Milan Criteria before Liver Transplantation
N. Mehta¹, J. Guy², C. Frenette³, P. Tabrizian⁴, M. Hoteit⁵, R. Dhanasekaran⁶, J. Dodge¹, M. L. Holzner⁴, L. Frankul³, S. Florman⁴, N. Parikh⁷, F. Yao¹
¹UCSF, San Francisco, CA, ²CPMC, San Francisco, CA, ³Scripps Hospital, La Jolla, CA, ⁴Mt Sinai, New York, NY, ⁵U. Pennsylvania, Philadelphia, PA, ⁶Stanford, Palo Alto, CA, ⁷U. Michigan, Ann Arbor, MI
*Purpose: Recent studies from United Network of Organ Sharing (UNOS) Region 5 reported excellent outcomes after liver transplantation (LT) after successful down-staging in HCC patients…
2019 American Transplant Congress
Inhibition of mTORC2 Causes Hyper Phosphorylation of ERK Induced by Co-Ligation of HLA-I and II Antibody
Y. Jin¹, J. Sinnet-Smith², E. Rozengurt², E. F. Reed¹
¹Pathology and Laboratory Medicine, University of California Los Angeles, Los Angeles, CA, ²Medicine, University of California Los Angeles, Los Angeles, CA
*Purpose: Transplant recipients developing donor specific antibodies (DSA) are at risk for antibody-mediated rejection (AMR). It has been reported that as many as 30% of…
2019 American Transplant Congress
The Spread of HIV Donation throughout a DSA
A. Friedman, E. Marquez, J. A. Lewis, K. Delli Carpini
LiveOnNY, New York, NY
*Purpose: Before passage of the HOPE act in late 2013, HIV infection was an absolute contraindication to organ donation. Retrospective review of the records of…
2019 American Transplant Congress
Outcomes for Robotic Pancreas Transplants in Obese Candidates
M. Spaggiari, K. A. Tulla, O. T. Okoye, C. Di Bella, P. Di Cocco, J. A. Almario Alvarez, I. G. Tzvetanov, E. Benedetti
University of Illinois at Chicago, Chicago, IL
*Purpose: Pancreas transplantation has evolved to include select overweight and obese diabetes mellitus (DM) patients. A robotic approach can be utilized to treat obese transplant…
2019 American Transplant Congress
The Use of dd-cfDNA as a Predictive Tool for Outcome Decreased Kidney Function
T. Alhamad¹, E. Poggio², D. Hiller³, S. Dholakia³, P. Sood⁴
¹Washington University School of Medicine, St. Louis, MO, ²Cleveland Clinic, Cleveland, OH, ³CareDx, Brisbane, CA, ⁴University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: A decline in estimated glomerular filtration rate (eGFR) during the first 12 months following kidney transplantation is associated with poor outcome and increased graft…