ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Clinical Trial of Allogeneic Islet Transplantation in the Treatment of Diabetes after Renal Transplantation

    W. liang, M. Hu, G. Peng, D. Zhou, C. Zeng, W. Zhou, q. Ye, Z. Wang

    Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases, Wuhan, China

    *Purpose: Diabetes after renal transplantation is one of the most serious complications after renal transplantation. It has a serious impact to the survival of kidney…
  • 2019 American Transplant Congress

    Ex Vivo Assessment of Marginal Human Kidneys Using Computed Tomography

    M. K. Harris1, J. R. DiRito2, H. Liu3, N. Boutagy3, C. Liu4, S. Hosgood2, D. Mulligan1, M. L. Nicholson2, A. Sinusas3, D. Haakinson1, G. T. Tietjen1

    1Surgery, Yale School of Medicine, New Haven, CT, 2Surgery, University of Cambridge, Cambridge, United Kingdom, 3Yale Translational Research Imaging Center, New Haven, CT, 4Radiology, Yale School of Medicine, New Haven, CT

    *Purpose: Thousands of ‘marginal’ organs are discarded each year despite a severe organ shortage. This has motivated development of new technologies, such as ex vivo…
  • 2019 American Transplant Congress

    Combined Thoracic-Liver Transplants Using Normothermic Machine Perfusion for Liver Preservation: A Case Series

    M. Rizzari, K. Crombez, S. Nagai, J. Stracke, A. Al-Kurd, K. Collins, A. Yoshida, M. Abouljoud

    Henry Ford Transplant Institute, Detroit, MI

    *Purpose: There is minimal data describing combined thoracic-liver transplants (tx) with normothermic machine perfusion (NMP) used for liver preservation as the thoracic tx is done.…
  • 2019 American Transplant Congress

    Pluripotent Stem Cell Differentiation: Delaying Forward Differentiation Signals Maintains Definitive Endoderm Phenotype for Cellular Transplantation

    J. Fair1, M. M. Shoja1, N. Liu1, I. Patrikeev2, M. Motamedi2, W. S. Fagg1

    1Surgery, University of Texas Medical Branch, Galveston, TX, 2Opthalmology and Visual Sciences, University of Texas Medical Branch, Galveston, TX

    *Purpose: Endodermal precursors (EP), derived in vitro from mouse pluripotent stem cell (PSC) sources, are capable of clinically useful engraftment in the unmodified (quiescent) liver…
  • 2019 American Transplant Congress

    Endogenous Erythropoietin is Required for Spontaneous Acceptance of Murine Renal Allografts

    J. Horwitz, P. Cravedi, P. Heeger

    Icahn School of Medicine at Mount Sinai, NY, NY

    *Purpose: B6 recipients spontaneously accept MHC-disparate renal allografts from allogeneic DBA/2 x B6 (H-2d x H-2b) F1 donors via mechanisms that are in part regulatory…
  • 2019 American Transplant Congress

    Novel Insights into Blocking the IL-6 / IL-6 Receptor Pathway after Pig Kidney Xenotransplantation in Baboons

    H. Hara1, G. Zhang1, H. Iwase1, T. Yamamoto1, D. Ayares2, D. E. Eckhoff1, D. K. Cooper1

    1Surgery, University of Alabama at Birmingham, Birmingham, AL, 2Revivicor Inc., Blacksburg, VA

    *Purpose: IL-6 plays an important role in inflammation. The aims of the study were (i) to measure IL-6 in serum in baboons that received IL-6…
  • 2019 American Transplant Congress

    Role of Innate Allorecognition Pathways in Mouse Renal Allograft Rejection

    D. Zhao1, H. Dai1, K. Abou-Daya1, A. Williams1, M. Oberbarnscheidt1, X. Li2, F. Lakkis1

    1Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA, 2Houston Methodist Hospital Immunobiology & Transplant Science Center, Houston, TX

    *Purpose: Allograft rejection is initiated by host immune system distinguishing between self and allogeneic non-self (allorecognition). Paired immunoglobulin-like receptor (PIR) and CD47 are molecules expressed…
  • 2019 American Transplant Congress

    Longer-Term Outcomes for Hepatitis C Virus Negative Recipients of Kidneys from Hepatitis C Virus Nucleic Acid Test Positive Donors: The THINKER Trial

    P. Reese1, P. Abt1, E. Blumberg1, R. Bloom1, D. Sawinski1, P. Porrett1, A. Woodards1, K. Reddy1, V. van Deerlin1, R. Hasz2, M. Levine1, R. McLean1, A. Sicilia1, D. Goldberg1

    1University of Penn, Philadelphia, PA, 2Gift of Life, Philadelphia, PA

    *Purpose: Two trials of transplanting hepatitis C virus (HCV) nucleic acid test (NAT) positive kidneys into HCV-negative recipients have been published, both with 100% HCV…
  • 2019 American Transplant Congress

    Robotic-Assisted versus Open Techniques for Living Donor Kidney Transplant Recipients: A Comparison Using Propensity Score Analysis

    F. Tinney, J. Stracke, S. Nagai, L. Malinzak, T. McEvoy, S. Mohamed Ilias, A. Yoshida

    Transplant Institute, Henry Ford Hospital, Detroit, MI

    *Purpose: Following rapid advancements in minimally invasive urology, living donor robotic-assisted kidney transplantation (RAKT) has developed into a feasible alternative to open kidney transplantation (OKT).…
  • 2019 American Transplant Congress

    Lower Rates of Epstein-Barr Virus Viremia and Post-Transplant Lymphoproliferative Disease in Pediatric Solid Organ Transplant Recipients Who Received Valganciclovir Prophylaxis

    E. A. Moulton1, M. Karandikar2, S. Bond3, S. Burchett2, T. Sharma2, F. M. Marty3

    1Baylor College of Medicine, Houston, TX, 2Boston Children's Hospital, Boston, MA, 3Brigham and Women's Hospital, Boston, MA

    *Purpose: Antiviral prophylaxis to prevent post-transplant lymphoproliferative disease (PTLD) remains controversial, but some data suggest that valganciclovir or ganciclovir use in Epstein-Barr virus (EBV) high-risk…
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