ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Donor-Derived Cell-Free DNA for Surveillance in Simultaneous Pancreas and Kidney Transplant Recipients, Can We Extrapolate from Kidney Transplant Alone?

    O. K. Olaitan1, S. Loeb1, E. Hetterman2, V. Peev1, S. Saltzberg1, M. Hertl1, S. Dholakia2

    1Rush University Medical Center, Chicago, IL, 2CareDx, Brisbane, CA

    *Purpose: Assessment and identification of early organ injury in Simultaneous Pancreas and Kidney (SPK) patients has clear clinical utility. This analysis was performed to establish…
  • 2019 American Transplant Congress

    Blockade of IL-1β and TNF-α Does Not Significantly Pose Risk or Affect Outcomes in Patients Infused with Microbial-Positive Autologous Islet Preparations

    K. Kumano1, C. Darden2, S. Vasu1, M. Lawrence1, B. Naziruddin3, A. Gupta3, E. Beecherl3, N. Onaca3

    1Baylor Scott and White Research Institute, Dallas, TX, 2Baylor University, Waco, TX, 3Baylor Simmons Transplant Institute, Dallas, TX

    *Purpose: We recently demonstrated that the combined use of anakinra (IL-1β blocker) and etanercept (TNF-α blocker) improved outcomes of islet autotransplantation after total pancreatectomy (TPIAT).…
  • 2019 American Transplant Congress

    Correlates of Significant Weight Changes Following Pancreas Alone Transplantation

    A. Arunachalam, F. Aziz, N. Garg, M. Mohamed, A. Djamali, J. Odorico, D. Mandelbrot, S. Parajuli

    University of Wisconsin, Madison, WI

    *Purpose: Significant weight change is defined as unintentional weight gain of ≥ 7% of body weight or unintentional weight loss of > 5% in one…
  • 2019 American Transplant Congress

    Evaluating the Predictive Utility of the Stanford Integrated Psychosocial Assessment for Transplantation (SIPAT) for Post-Transplant Outcomes in Moderate to High-Risk Liver Transplant Candidates

    P. Sheiner, S. Spence, D. Gleason, J. Riley, M. Einstein, E. UrtasunSotil, C. Rochon, B. Maneckshana, O. Serrano

    Hartford Hospital, Hartford, CT

    *Purpose: Previous studies suggest the Stanford Integrated Psychosocial Assessment for Transplantation (SIPAT) is predictive of post-transplant outcomes in multiorgan transplant candidates. We aim to determine…
  • 2019 American Transplant Congress

    The Impact of Acute Rejection in Heart Transplantation on Post-Transplant Malignancy

    K. Kamrani1, A. Okoh2, D. Hanos1, M. Camacho1, M. Zucker2, K. Clarke1

    1Dept. of Surgery, Newark Beth Israel Medical Center, Newark, NJ, 2Dept. of Medicine, Newark Beth Israel Medical Center, Newark, NJ

    *Purpose: Compared with the general population, an increased incidence of skin cancers and lymphomas have been shown in orthotopic heart transplant (OHT) recipients. However, the…
  • 2019 American Transplant Congress

    First Report and Mechanistic Analysis of Chronic GVHD after Solid Organ Transplantation

    J. Weiner, N. Svetlicky, J. Schmidt, J. Kang, M. Sadat, A. Karaballa, S. Moturi, O. Aguirre, J. Hawksworth, C. Matsumoto, T. Fishbein, A. Kroemer

    Georgetown University Hospital, Washington, DC

    *Purpose: Chronic graft-versus-host disease (cGVHD) occurs late after bone marrow transplantation and is associated with a characteristic lichenoid rash (cutaneous sclerosis) and effects on multiple…
  • 2019 American Transplant Congress

    Specific Donor/Recipient HLA Disparities are Associated with Better Long-Term Kidney Allograft Survival among 4-, 5-, and 6-HLA (A/B/DR)-Mismatched Pairs

    D. Bekbolsynov, H. Zhang, B. Mierzejewska, M. Rees, K. Xu, S. Stepkowski

    University of Toledo, Toledo, OH

    *Purpose: The vast majority of deceased donor kidneys are allocated without any consideration for the HLA disparities, which may improve or worsen the survival the…
  • 2019 American Transplant Congress

    Vimentin Inhibition Improves Post-Transplant Survival in a Mouse Renal Transplant Model

    R. Lopez-Soler1, Z. Zhang2, H. Chin3, J. Wang4, K. Ridge5

    1Albany Medical College, Albany, NY, 2Microsurgery Core, Comprehensive Transplant Center, Northwestern University, Feinberg School of Medicine, Chicago, IL, 3Molecular and Cellular Physiology, Albany Medical College, Albany, NY, 4Microsurgery Core, Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL, 5Northwestern Univesity, Feinberg School of Medicine, Chicago, IL

    *Purpose: Most renal transplants ultimately fail secondary to chronic allograft nephropathy (CAN). The development of Epithelial to Mesenchymal Transition (EMT) in renal tubular epithelial cells…
  • 2019 American Transplant Congress

    The High Burden of Vaccine Preventable Infections Following Pediatric Solid Organ Transplant

    A. G. Feldman1, B. L. Beaty2, D. Curtis3, E. Juarez-Colunga2, A. Kempe4

    1Pediatric Gastroenterology, Hepatology and Nutrition, University of Colorado, Aurora, CO, 2University of Colorado, Aurora, CO, 3Pediatric Infectious Diseases, University of Colorado, Aurora, CO, 4Pediatrics, University of Colorado, Aurora, CO

    *Purpose: Pediatric transplant recipients are at risk for vaccine preventable infections due to immunosuppression, suboptimal response to vaccines before and after transplant, and potential under-immunization…
  • 2019 American Transplant Congress

    Variable Glycosylations of Anti-HLA Antibodies Detected with Single Antigen Beads in Kidney Transplant Recipients

    Y. Chang1, N. Lemp2, J. Cicciarelli1, T. Shah3, D. Min4

    1Mendez National Institute of Transplantation Foundation, Los Angeles, CA, 2Transplantation Research, Mendez National Institute of Transplantation Foundation, Los Angeles, CA, 3St. Vincent Medical Center, Los Angeles, CA, 4Western Univ of Health Sciences, Pomona, CA

    *Purpose: Differential glycosylation of Immunoglobulin G (IgG) is known to affect its effector functions by modulating interactions with its binding partners, such as C1q or…
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