ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Early Tacrolimus Trough Attainment in De Novo Kidney Transplant Recipients Treated with LCP-Tacrolimus (LCPT) vs. Immediate-Release Tacrolimus (IR-Tac)

    K. Budde1, S. Bunnapradist2, S. J. Patel3, D. R. Stevens3, U. Meier-Kriesche3, B. Suwelack4

    1Charité University Medicine Berlin, Berlin, Germany, 2UCLA Medical Center, Los Angeles, CA, 3Veloxis Pharmaceuticals Inc., Cary, NC, 4University Hospital of Münster, Münster, Germany

    *Purpose: Early achievement of therapeutic tacrolimus concentrations has been associated with reduced rates of acute rejection. A prospective, randomized, controlled study demonstrated safe and efficacious…
  • 2019 American Transplant Congress

    Relationship between Comorbilities and Infectious Disease in Kidney Transplant Recipients Receiving Rituximab

    A. Molina-Andújar1, E. Hermida1, J. Rovira2, F. Cofan1, P. Ventura-Aguiar1, N. Esforzado1, V. Torregrosa1, D. Cucchiari1, E. de Souza1, I. Revuelta1, F. Oppenheimer1, F. Diekmann1, G. Piñeiro1

    1Renal Transplant Unit, Hospital Clínic de Barcelona, Barcelona, Spain, 2Laboratori Experimental de Nefrologia i Trasplantament, IDIBAPS, Barcelona, Spain

    *Purpose: Rituximab is commonly used in the context of kidney transplantation. Evidence about infectious complications and its relationship with predictive factors is scarce. The aim…
  • 2019 American Transplant Congress

    Urinary Biomarkers of Kidney Injury in Liver Transplant Recipients with Calcineurin Inhibitors Based Immunosuppression

    D. Maluf1, V. Bontha1, A. Bajwa2, A. Abdelaal1, C. Koo1, J. D. Eason2, V. Mas2

    1UTHSC, Memphis, TN, 2Transplant Institute, Memphis, TN

    *Purpose: Renal dysfunction post solid organ transplantation is common and associated with several risk factors. Messenger RNA encoding for genes expressed along the nephron and…
  • 2019 American Transplant Congress

    Renal Failure after Liver Transplantation: Benefits from a Little Pinch of KALT

    R. Ruiz1, K. Holmes2, G. McKenna1, N. Onaca1, G. Testa1, H. Fernandez1, J. Bayer1, A. Wall1, E. Martinez1, E. Martinez1, A. Gupta1, R. Goldstein1, G. Klintmalm1

    1Baylor All Saints Medical Center, Fort Worth, TX, 2Medical City Fort Worth, Fort Worth, TX

    *Purpose: The development and consequences of renal failure after liver transplantation (LT) are well-chronicled. Kidney after liver transplantation (KALT) is the preferred treatment in this…
  • 2019 American Transplant Congress

    Functional Measures of Frailty and Not Sarcopenia Predict Mortality in a Prospective Cohort of Liver Transplant Candidates

    R. Sharma, R. Rosenblatt, R. Knotts, J. Pisa, E. Verna

    Division of Liver Diseases and Transplantation, Columbia Univeristy Medical Center, New York, NY

    *Purpose: Sarcopenia determined by single slice measures of abdominal imaging have been correlated with liver transplant (LT) outcomes. However, in end-stage liver disease (ESLD), these…
  • 2019 American Transplant Congress

    Donor Derived Tuberculosis in Solid Organ Transplantation in the United States: 10 Years of UNOS Ad Hoc Disease Transmission Advisory Committee Experience

    M. F. Malinis1, R. LaHoz1, G. Vece2, S. Tlusty2, S. Aslam1, R. Bag1, J. Bucio1, L. Danziger-Isakov1, D. F. Florescu1, M. Rana1, C. Wolfe1, M. G. Michaels1

    1DTAC, Richmond, VA, 2UNOS, Richmond, VA

    *Purpose: Mycobacterium tuberculosis can be transmitted via organ donation. Failure to recognize tuberculosis (TB) may result in significant morbidity and mortality. Currently, donor screening for…
  • 2019 American Transplant Congress

    Evaluation of Pneumocystis jirovecii Pneumonia Prophylaxis among Kidney and Liver Transplant Recipients; Trimethoprim/Sulfamethoxazole vs Alternative Therapies

    E. Aldag, C. Pagels, R. Pedersen, I. Nadeem, V. Gunabushanam, A. Sahajpal, T. J. Dilworth

    Aurora St Luke's Medical Center, Milwaukee, WI

    *Purpose: To describe Pneumocystis Jirovecii Pneumonia (PJP) prophylaxis (ppx) practices in our transplant recipients and to determine its safety and efficacy.*Methods: Retrospective review of kidney…
  • 2019 American Transplant Congress

    Impact of Vancomycin-Resistant Enterococci Gut Colonization on Liver Transplant Outcomes

    D. Chiang, T. C. Dingle, S. Belga, D. Kabbani, J. Walter, J. G. Abraldes, C. Cervera

    University of Alberta, Edmonton, AB, Canada

    *Purpose: Vancomycin-resistant enterococci (VRE) colonization is common in liver transplant candidates. In addition to the risk of invasive enterococcal infections, dominance of VRE colonization in…
  • 2019 American Transplant Congress

    Activation of Oxidative Stress-Adoptive Responses during Extended Ex Situ Heart Perfusion

    S. Hatami, X. Qi, M. Buchko, C. W. White, S. Bozso, S. Himmat, J. Nagendran, D. H. Freed

    Department of Surgery, University of Alberta, Edmonton, AB, Canada

    *Purpose: Cardiac function declines in a time-related fashion during ex situ heart perfusion (ESHP) regardless of ventricular load status. We have previously shown that the…
  • 2019 American Transplant Congress

    Metabolic Profiling of Steatotic Human Livers during Ex-Vivo Normothermic Machine Perfusion

    S. Raigani1, N. Karimian2, V. Huang2, S. Geerts2, S. Nagpal2, K. Uygun1, M. Yarmush1, H. Yeh1

    1Transplant Surgery, Massachusetts General Hospital, Boston, MA, 2Center for Engineering in Medicine, Shriners Childrens Hospital, Boston, MA

    *Purpose: Nearly 40-60% of discarded livers are due to steatosis because of poor recovery from ischemia-reperfusion injury and compromised post-transplant function. We evaluated steatotic (ST)…
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