Am J Transplant, Volume 19, Suppl 3 Archives - Page 140 of 214 - ATC Abstracts

2019 American Transplant Congress
Poor Long-Term Outcome of Liver Transplant Recipients with Preexisting Renal Insufficiency
M. Sterneck¹, M. Touma¹, T. Horvatits², S. Pischke², U. Herden³, A. Lohse², L. Fischer³
¹University Transplant Center, University Medical Center Hamburg Eppendorf, Hamburg, Germany, ²Department of Medicine, University Medical Center Hamburg Eppendorf, Hamburg, Germany, ³Department of Visceral Transplantation, University Medical Center Hamburg Eppendorf, Hamburg, Germany
*Purpose: Due to the MELD based allocation system the number of patients undergoing orthotopic liver transplantation (OLT) with severely impaired renal function has markedly increased.…
2019 American Transplant Congress
Extreme Hyponatremia as a Risk Factor for Early Mortality after Liver Transplantation in the Model for End-Stage Liver Disease-Sodium Period
H. Mouzaihem, M. Safwan, L. C. Chau, D. Moonka, M. Abouljoud, S. Nagai
Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI
*Purpose: While we reported that implementation of MELD-Na based liver allocation improved waitlist outcomes in patients with hyponatremia, its impact on post-transplant outcomes in this…
2019 American Transplant Congress
A Randomized Pilot Trial of Home-Based Physical Activity Plus Dietary Intervention to Improve Physical Function in Patients with Advanced Liver Disease
H. Chen¹, A. A. Ferrando², M. G. White², M. Pauly², T. Bartter², M. A. Dunn¹, W. R. Kim³, A. Duarte-Rojo¹
¹T.E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, ²University of Arkansas for Medical Sciences, Little Rock, AR, ³Stanford University, Palo Alto, CA
*Purpose: Deconditioning and frailty are prevalent among liver transplant (LTx) candidates and prehabilitation programs have been proposed in order to improve clinical outcomes. However, few…
2019 American Transplant Congress
Donor Derived Strongyloidiasis, a Preventable Event
R. M. La Hoz¹, G. Vece², L. Danziger-Isakov¹, D. Florescu¹, M. Malinis¹, K. Lilly¹, L. Strasfeld¹, R. P. Wood¹, S. Tlusty², C. R. Wolfe¹, M. G. Michaels¹
¹DTAC, Richmond, VA, ²UNOS, Richmond, VA
*Purpose: In the US, deceased donor screening for Strongyloides started in 2010. By 2013 10% of the OPOs had implemented screening practices. Recipients of sero-positive…
2019 American Transplant Congress
Predictors of Clostridium difficile Infection and Recurrence among 2,622 Solid Organ Transplant Recipients
A. Schluger, R. Rosenblatt, R. Knotts, E. Verna, M. Pereira
Columbia University, New York, NY
*Purpose: Clostridium difficile infection (CDI) is common after solid organ transplant (SOT) and is associated with high morbidity and mortality. We assessed incidence, risk factors…
2019 American Transplant Congress
The Economic Impact of Surgical Site Infections in Liver Transplantation
Y. Natori¹, D. Kumar², A. Humar², S. Husain², C. Rotstein³
¹Miami Transplant Institute, University of Miami, Miami, FL, ²Transplant Infectious Diseases, University of Toronto, Toronto, ON, Canada, ³University of Toronto, Toronto, ON, Canada
*Purpose: Complications arising after liver transplantation result in additional healthcare costs. Previous studies have not evaluated the impact of surgical site infections on healthcare costs…
2019 American Transplant Congress
Inhibition of TLR4 Mediated Programmed Necrosis Does Not Improve Graft Function and Histology in a Murine Kidney Transplant Model
S. Jain¹, R. Plenter², T. Nydam², A. Jani¹
¹Renal Division, University of Colorado, Aurora, CO, ²Transplant Microsurgery Program, University of Colorado, Aurora, CO
*Purpose: Human Delayed Graft Function (DGF) is associated with upregulation of basolateral tubular TLR4 but whether TLR4 causes DGF is unknown. TLR4 has been shown…
2019 American Transplant Congress
Ischemia-Free Liver Transplantation Protects Bile Duct from Ischemia/Reperfusion Injury
J. Yang, S. Huang, Z. Zhang, Q. Zhao, W. Ju, Z. Zhu, Y. Tang, L. Wang, Y. Zhang, C. Sun, L. Wu, Z. Guo, X. He
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
*Purpose: Ischemia-free liver transplantation (IFLT), based on normothermic machine perfusion and innovations in surgical technique, can provide continue blood supply from procurement to implantation that…
2019 American Transplant Congress
The Negative Costimulatory Pd-1/pd-l1 Pathway Is Upregulated In Early Cell-mediated Rejection
T. Kurashige, R. Khedraki, K. Keslar, N. Dvorina, W. Baldwin
Cleveland Clinic Main Campus, Lerner Research Institute, Cleveland, OH
*Purpose: Extensive transcript analysis has been performed on grafts at the time of rejection, but gene expression preceding overt rejection is less well studied.*Methods: We…
2019 American Transplant Congress
Metabolomic Study Of Sarcopenia In Patients Prior To Liver Transplantation
S. Ries,¹, N. J. Skill¹, E. Campbell¹, R. Daniel², C. A. Kubal¹, M. S. Richard¹, M. A. Maluccio¹
¹Surgery, Indiana University, Indianapolis, IN, ²University of Washington, Seattle, WA
*Purpose: Sarcopenia is defined as the loss of muscle mass, typically associated with aging, but frequently appearing in liver disease patients. In particular, sarcopenia present…